nf-core Pipelines Skills Index

nf-core Pipelines Skills Index is a skill for Claude Code, Codex from aristoteleo/PantheonOS. It costs 30 tokens per session (1,143 once invoked), scanned A, original, BSD-2-Clause.

An index of nf-core skills, covering nf-core's community-maintained Nextflow workflows for processing biological sequencing data.

In plain words
What is it for?
Use it to set up Nextflow, configure computing resources, resume or run workflows offline, and process single-cell or bulk RNA sequencing data.
Why use it?
It helps choose and configure a tested workflow when raw or processed omics data must be handled consistently on a laptop, cluster, or cloud system.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to set up Nextflow, configure computing resources, resume or run workflows offline, and process single-cell or bulk RNA sequencing data.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/aristoteleo/pantheonos/nfcore
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add aristoteleo/PantheonOS --skill nfcore
Clone the repo
git clone --depth 1 https://github.com/aristoteleo/PantheonOS

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for nf-core Pipelines Skills Index

README.md
[![agentmods](https://agentmods.dev/badge/skills/aristoteleo/pantheonos/nfcore/github.svg)](https://agentmods.dev/skills/aristoteleo/pantheonos/nfcore)
Your own site
<a href="https://agentmods.dev/skills/aristoteleo/pantheonos/nfcore"><img src="https://agentmods.dev/badge/skills/aristoteleo/pantheonos/nfcore/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for nf-core Pipelines Skills Index

Your own site · 80×15
<a href="https://agentmods.dev/skills/aristoteleo/pantheonos/nfcore"><img src="https://agentmods.dev/badge/skills/aristoteleo/pantheonos/nfcore.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 30 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,143 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00030 $0.01143
Opus 5 $0.00015 $0.00571
Sonnet 5 $0.00006 $0.00229
Haiku 4.5 $0.00003 $0.00114

Measured 9d ago against content hash fc9e2f00b977, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-08, from the pricing page.

Security

Grade A, and why

nf-core Pipelines Skills Index scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 9d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

pantheon/factory/templates/skills/omics/upstream_processing/nfcore/SKILL.md · 138 lines

How it starts

The opening of the file, as written. The whole thing — 138 lines — stays where its author put it; the contents beside it link to each section on GitHub.

nf-core Pipelines Skills

nf-core is a community-driven collection of 143+ curated Nextflow pipelines for bioinformatics. All pipelines are open-source (MIT), rigorously tested, and run portably on laptops, HPCs, and cloud platforms with automated dependency management via Docker, Singularity, or Conda.

Available Skills

Getting Started & Usage

Installation, configuration, and common usage patterns for running any nf-core pipeline on local machines, HPC clusters, or cloud environments.

Skill file: nfcore_usage.md

When to use:

  • First time setting up Nextflow and nf-core
  • Configuring pipelines for your HPC cluster or cloud environment
  • Understanding resource management, resume, and offline execution
  • Looking up nf-core CLI tool commands

Single-Cell & Bulk RNA-seq Pipelines

Pipelines for processing single-cell RNA-seq (10x, Drop-seq, Smart-seq) and bulk RNA-seq data from raw FASTQs to count matrices.

Skill file: nfcore_transcriptomics.md

When to use:

  • Processing 10x Chromium, Drop-seq, or Smart-seq scRNA-seq data
  • Running downstream single-cell analysis (doublet removal, integration, annotation)
  • Processing bulk RNA-seq with STAR, HISAT2, Salmon, or Kallisto
  • Generating gene/transcript count matrices and QC reports

Spatial Omics Pipelines

Pipelines for spatial transcriptomics platforms including Visium, Xenium, MERSCOPE, CosMX, and molecular cartography.

Skill file: nfcore_spatial.md

When to use:

  • Processing 10x Visium or Visium HD data
  • Analyzing Xenium in situ data with cell segmentation
  • Running technology-agnostic spatial pipelines (sopa)
  • Processing Resolve Bioscience Molecular Cartography data

Epigenomics Pipelines

Pipelines for chromatin accessibility, histone modification, protein-DNA interaction, and DNA methylation profiling.

Skill file: nfcore_epigenomics.md

Read the full file on GitHub · 138 lines

Files

What ships with it

7 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 9d ago First seen · 138 lines · 30 tokens per session scan A fc9e2f00b977

Subscribe to this mod's changes

nf-core Pipelines Skills Index is a skill published in the GitHub repository aristoteleo/PantheonOS (484 stars, last pushed today), licensed BSD-2-Clause. It adds 30 tokens to every session and 1,143 once invoked, about $0.0002 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

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