Cell Segmentation Skills Index

Cell Segmentation Skills Index is a skill for Claude Code, Codex from aristoteleo/PantheonOS. It costs 35 tokens per session (845 once invoked), scanned A, original, BSD-2-Clause.

An index of tools that separate individual cells or nuclei in microscopy images, producing a mask for each detected object.

In plain words
What is it for?
Use it to choose and apply Cellpose, InstanSeg, StarDist, Mesmer, micro-sam, or CellSAM for cell and nucleus detection, annotation, three-dimensional work, or tracking.
Why use it?
It helps select a suitable method when images vary in quality, speed requirements, object shape, or whether cells and nuclei both need to be identified.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to choose and apply Cellpose, InstanSeg, StarDist, Mesmer, micro-sam, or…

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/aristoteleo/pantheonos/segmentation
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add aristoteleo/PantheonOS --skill segmentation
Clone the repo
git clone --depth 1 https://github.com/aristoteleo/PantheonOS

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for Cell Segmentation Skills Index

README.md
[![agentmods](https://agentmods.dev/badge/skills/aristoteleo/pantheonos/segmentation.svg)](https://agentmods.dev/skills/aristoteleo/pantheonos/segmentation)
Your own site
<a href="https://agentmods.dev/skills/aristoteleo/pantheonos/segmentation"><img src="https://agentmods.dev/badge/skills/aristoteleo/pantheonos/segmentation.svg" alt="Measured on agentmods" height="20"></a>
Per session 35 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 845 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00035 $0.00845
Opus 5 $0.00017 $0.00423
Sonnet 5 $0.00007 $0.00169
Haiku 4.5 $0.00003 $0.00085

Measured 7d ago against content hash ca54ceecd656, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-06, from the pricing page.

Security

Grade A, and why

Cell Segmentation Skills Index scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 7d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

pantheon/factory/templates/skills/bio_image_processing/segmentation/SKILL.md · 90 lines

How it starts

The opening of the file, as written. The whole thing — 90 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Cell & Nucleus Segmentation Skills

Instance segmentation tools for cells and nuclei in microscopy images. Use the tool selection guide below to choose the right method, then load the corresponding skill file for detailed usage.

Tool Selection Guide

Goal Recommended Tool Speed Tested
Best overall accuracy Cellpose-SAM (v4.x) Moderate (~310s/1024px CPU) ✅ 955 cells
Fastest inference InstanSeg Fast (~7s/1024px CPU) ✅ 586 cells
Low quality / noisy images Cellpose 3 (image restoration) Moderate
Round nuclei only StarDist Fastest (~0.5s) ✅ 150 cells
Whole-cell (nucleus + membrane) Mesmer / DeepCell Moderate ⚠️ install issues
Interactive annotation / 3D / tracking micro-sam Slow ⚠️ Python 3.10+
Fully automatic, no prompts CellSAM Moderate ⚠️ Python 3.10+

[!TIP] Start with Cellpose (default in v4.x) for most tasks. It has the best generalization. Switch to InstanSeg if speed matters or you need simultaneous nuclei + cell masks.

[!WARNING] Environment isolation is important. These tools have conflicting dependencies. Cellpose/InstanSeg use PyTorch; StarDist/Mesmer use TensorFlow; SAM-based tools need Python 3.10+. Create separate virtual environments for each tool family:

  • venv-cellpose: Cellpose + InstanSeg (both PyTorch)
  • venv-stardist: StarDist (TensorFlow, numpy<2)
  • venv-deepcell: Mesmer/DeepCell (TensorFlow, strict numpy version)
  • venv-sam: micro-sam / CellSAM (Python 3.10+)

Available Skills

Cellpose

General-purpose cell and nucleus segmentation using Cellpose v4.x (includes Cellpose-SAM with ViT-L backbone). Image restoration, fine-tuning, and 3D segmentation.

Skill file: cellpose.md

When to use: Default choice for most segmentation tasks.

InstanSeg

Fast cell and nucleus segmentation with dual output (nuclei + cells simultaneously). Supports multiplexed images via ChannelNet.

Read the full file on GitHub · 90 lines

Files

What ships with it

5 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 7d ago First seen · 90 lines · 35 tokens per session scan A ca54ceecd656

Subscribe to this mod's changes

Cell Segmentation Skills Index is a skill published in the GitHub repository aristoteleo/PantheonOS (482 stars, last pushed 4d ago), licensed BSD-2-Clause. It adds 35 tokens to every session and 845 once invoked, about $0.0002 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

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