Skill Claude Code
Validate whether a marker set supports a proposed cell type or cell state and explain the main caveats.
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Skill Claude Code
Validate whether a marker set supports a proposed cell type or cell state and explain the main caveats.
Skill Claude Code
Build positive and negative marker panels for a cell type or state and explain the confidence of the proposed panel.
Skill Claude Code
Convert between molarity, mass, and volume using molecular weight.
Skill Claude Code
Look up gene description and location via NCBI Gene (esearch/efetch).
Skill Claude Code
Advise on normalization for scRNA (library size, log, SCTransform, etc.).
Skill Claude Code
Map genes across species and explain confidence, ambiguity, and biological caveats.
Skill Claude Code
Triage a paper for biological relevance, extract the main claims, and separate evidence-backed takeaways from abstract-only impressions.
Skill Claude Code
Check whether paralogs or compensatory family members may weaken interpretation of a perturbation target.
Skill Claude Code
Look up pathway or GO/Reactome/KEGG term definitions and key genes.
Skill Claude Code
Suggest a control strategy for perturbation experiments, including non-targeting, positive, and interpretation controls.
Skill Claude Code
Compare gene signatures across perturbations and suggest clustering or grouping.
Skill Claude Code
Estimate the cell budget and practical coverage needed for a Perturb-seq design.
Skill Claude Code
Generate a 96- or 384-well plate map for perturbations and replicates.
Skill Claude Code
Advise on PCR primer design (Tm, length, GC%, avoiding secondary structure).
Skill Claude Code
Retrieve a lab protocol or SOP from the local knowledge base and summarize the parts that matter for the current experiment.
Skill Claude Code
Recommend a replicate-aware pseudobulk strategy for single-cell differential expression and explain the design choices.
Skill Claude Code
Fetch and summarize a PubMed article by PMID (abstract, key methods, key findings).
Skill Claude Code
Search PubMed for articles by query; return top N PMIDs with titles, year, journal, and link.
Skill Claude Code
Parse common pipeline log/output and summarize metrics and status.
Skill Claude Code
Propose safe commands and directory hygiene for running a pipeline.
Skill Claude Code
Turn single-cell RNA-seq summary metrics into a practical QC checklist with explicit assumptions and threshold recommendations.
Skill Claude Code
Suggest Scanpy/Python commands for basic scRNA QC (filtering, mito, UMI).
Skill Claude Code
Generate an sbatch script template for GPU or CPU jobs (Slurm).
Skill Claude Code
Rank perturbation targets by drugability, pathway relevance, and safety given constraints.
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