solublempnn

solublempnn is a skill for Claude Code, Codex from BioTender-max/ProteinClaw. It costs 91 tokens per session (448 once invoked), scanned A, original, no licence file.

A skill for designing protein sequences with SolubleMPNN, a tool that favors sequences likely to dissolve well in laboratory solutions.

In plain words
What is it for?
Designing proteins for E. coli production, improving solubility, reducing aggregation risk, and supporting higher-yield expression.
Why use it?
It helps reduce aggregation and inclusion bodies, which are clumps of protein that can form when producing proteins in E. coli bacteria.

Skill for Claude CodeCodex

Which agent this was written for is unclear — body not stored (licence); the path alone says nothing.

Good fit Designing proteins for E. coli production, improving solubility, reducing aggregation risk, and supporting higher-yield expression.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/biotender-max/proteinclaw/solublempnn
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add BioTender-max/ProteinClaw --skill solublempnn
Clone the repo
git clone --depth 1 https://github.com/BioTender-max/ProteinClaw

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for solublempnn

README.md
[![agentmods](https://agentmods.dev/badge/skills/biotender-max/proteinclaw/solublempnn.svg)](https://agentmods.dev/skills/biotender-max/proteinclaw/solublempnn)
Your own site
<a href="https://agentmods.dev/skills/biotender-max/proteinclaw/solublempnn"><img src="https://agentmods.dev/badge/skills/biotender-max/proteinclaw/solublempnn.svg" alt="Measured on agentmods" height="20"></a>
Per session 91 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 448 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin unknown No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00091 $0.00448
Opus 5 $0.00046 $0.00224
Sonnet 5 $0.00018 $0.00090
Haiku 4.5 $0.00009 $0.00045

Measured 8d ago against content hash f580b971d87c, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-08, from the pricing page.

Security

Grade A, and why

solublempnn scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 8d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/solublempnn/SKILL.md · 61 lines

The source is not reproduced here

No licence file

A repository with no LICENSE is all rights reserved by default, so the body is not copied here. The metadata, the measurements and the link are.

Read it on GitHub

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 8d ago First seen · 61 lines · 91 tokens per session scan A f580b971d87c

Subscribe to this mod's changes

solublempnn is a skill published in the GitHub repository BioTender-max/ProteinClaw (11 stars, last pushed 6mo ago), with no licence file. It adds 91 tokens to every session and 448 once invoked, about $0.0005 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

Related

Other skills, from other repositories

solublempnn

Solubility-optimized protein sequence design using SolubleMPNN. Use this skill when: (1) Designing for E. coli expression, (2) Optimizing solubility of designed proteins, (3) Reducing aggregation propensity, (4) Need high-yield expression, (5) Avoiding inclusion body formation. For standard design, use proteinmpnn.…

adaptyvbio/protein-design-skills · 91 tokens

solublempnn

Solubility-optimized protein sequence design using SolubleMPNN. Use this skill when: (1) Designing for E. coli expression, (2) Optimizing solubility of designed proteins, (3) Reducing aggregation propensity, (4) Need high-yield expression, (5) Avoiding inclusion body formation. For standard design, use proteinmpnn.…

zongtingwei/Bioclaw_Skills_Hub · 91 tokens

solublempnn

Solubility-optimized protein sequence design using SolubleMPNN. Use this skill when: (1) Designing for E. coli expression, (2) Optimizing solubility of designed proteins, (3) Reducing aggregation propensity, (4) Need high-yield expression, (5) Avoiding inclusion body formation. For standard design, use proteinmpnn.…

BioTender-max/awesome-bio-agent-skills · 91 tokens

proteinmpnn

Design protein sequences using ProteinMPNN inverse folding. Use this skill when: (1) Designing sequences for RFdiffusion backbones, (2) Redesigning existing protein sequences, (3) Fixing specific residues while designing others, (4) Optimizing sequences for expression or stability, (5) Multi-state or negative design.…

adaptyvbio/protein-design-skills · 106 tokens

ligandmpnn

Ligand-aware protein sequence design using LigandMPNN. Use this skill when: (1) Designing sequences around small molecules, (2) Enzyme active site design, (3) Ligand binding pocket optimization, (4) Metal coordination site design, (5) Cofactor binding proteins. For standard protein design, use proteinmpnn. For…

adaptyvbio/protein-design-skills · 86 tokens

proteinmpnn

Design protein sequences using ProteinMPNN inverse folding. Use this skill when: (1) Designing sequences for RFdiffusion backbones, (2) Redesigning existing protein sequences, (3) Fixing specific residues while designing others, (4) Optimizing sequences for expression or stability, (5) Multi-state or negative design.…

zongtingwei/Bioclaw_Skills_Hub · 106 tokens