biosimspace

biosimspace is a skill for Claude Code, Codex from dtunai/agent-skills-for-compute. It costs 59 tokens per session (3,175 once invoked), scanned A, original, MIT.

A Python framework for building biomolecular simulations that can run with different simulation engines, including AMBER, GROMACS, NAMD, OpenMM, and SOMD. It covers preparing molecules, running molecular dynamics, and selected free-energy and enhanced-sampling workflows.

In plain words
What is it for?
Use it to read and prepare molecular structures, add force-field parameters, solvate systems, minimize and equilibrate them, run production simulations, and perform free-energy or metadynamics calculations.
Why use it?
It lets a workflow stay mostly the same when the underlying simulation engine changes, reducing engine-specific setup work.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to read and prepare molecular structures, add force-field parameters, solvate systems, minimize and equilibrate them, run production simulations, and perform free-energy or metadynamics calculations.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/dtunai/agent-skills-for-compute/biosimspace
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add dtunai/agent-skills-for-compute --skill biosimspace
Clone the repo
git clone --depth 1 https://github.com/dtunai/agent-skills-for-compute

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for biosimspace

README.md
[![agentmods](https://agentmods.dev/badge/skills/dtunai/agent-skills-for-compute/biosimspace/github.svg)](https://agentmods.dev/skills/dtunai/agent-skills-for-compute/biosimspace)
Your own site
<a href="https://agentmods.dev/skills/dtunai/agent-skills-for-compute/biosimspace"><img src="https://agentmods.dev/badge/skills/dtunai/agent-skills-for-compute/biosimspace/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for biosimspace

Your own site · 80×15
<a href="https://agentmods.dev/skills/dtunai/agent-skills-for-compute/biosimspace"><img src="https://agentmods.dev/badge/skills/dtunai/agent-skills-for-compute/biosimspace.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 59 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 3,175 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00059 $0.03175
Opus 5 $0.00030 $0.01588
Sonnet 5 $0.00012 $0.00635
Haiku 4.5 $0.00006 $0.00317

Measured 10d ago against content hash 295bb5204322, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-10, from the pricing page.

Security

Grade A, and why

biosimspace scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 10d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/biosimspace/SKILL.md · 370 lines

How it starts

The opening of the file, as written. The whole thing — 370 lines — stays where its author put it; the contents beside it link to each section on GitHub.

BioSimSpace

Engine-agnostic Python framework for biomolecular simulation. Write portable workflows once — BioSimSpace translates to AMBER, GROMACS, NAMD, OpenMM, or SOMD at runtime.

Official Sources:

Quick Start

# Install via conda (recommended)
conda create -n openbiosim -c conda-forge -c openbiosim biosimspace
conda activate openbiosim

# Optional: install MD engines
conda install -c conda-forge ambertools gromacs
import BioSimSpace as BSS

Architecture

Module Purpose
BSS.IO Read/write molecules (PDB, MOL2, GRO, PRM7, RST7, SDF, DCD...)
BSS.Parameters Parameterise with force fields (ff14SB, GAFF, GAFF2, OpenFF...)
BSS.Solvent Solvate in water boxes (TIP3P, SPC/E, TIP4P, OPC...)
BSS.Protocol Engine-agnostic simulation protocols
BSS.Process Engine-specific process drivers (Amber, Gromacs, Namd, OpenMM, Somd)
BSS.MD Auto-select engine and run
BSS.FreeEnergy Relative FEP and ATM (alchemical transfer method)
BSS.Align Atom mapping, alignment, merging for FEP
BSS.Metadynamics Enhanced sampling via PLUMED
BSS.Convert Convert between BSS, RDKit, OpenMM, Sire representations
BSS.Box Simulation box generators (cubic, rhombic dodecahedron, truncated octahedron)
BSS.Types Physical quantities (Length, Temperature, Time, Energy, Pressure...)
BSS.Units Unit constants (BSS.Units.Length.nanometer, etc.)
BSS.Gateway Node I/O for reusable workflow components
BSS.Notebook Visualization (plots, 3D views via NGLView)
BSS.Trajectory Trajectory analysis wrapper
BSS.Stream Serialization/checkpointing

Supported Engines

Engine Process Class Detection
AMBER BSS.Process.Amber AMBERHOME env var
GROMACS BSS.Process.Gromacs gmx/gmx_mpi in PATH or GROMACSHOME
NAMD BSS.Process.Namd namd2/namd3 in PATH
OpenMM BSS.Process.OpenMM Python import
SOMD BSS.Process.Somd Part of Sire/OpenBioSim stack

Read the full file on GitHub · 370 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 10d ago First seen · 370 lines · 59 tokens per session scan A 295bb5204322

Subscribe to this mod's changes

biosimspace is a skill published in the GitHub repository dtunai/agent-skills-for-compute (2 stars, last pushed 6mo ago), licensed MIT. It adds 59 tokens to every session and 3,175 once invoked, about $0.0003 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-31.

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