hypothesis-generation

hypothesis-generation is a skill for Claude Code from foryourhealth111-pixel/Vibe-Skills. It costs 73 tokens per session (2,539 once invoked), scanned A, a copy of hypothesis-generation, Apache-2.0.

A structured method for turning observations into testable scientific explanations. It compares possible explanations, predicts what each would imply, and suggests experiments to check them.

In plain words
What is it for?
Use it to formulate hypotheses, design experiments, compare mechanisms, make predictions, and plan scientific studies.
Why use it?
It helps move from a vague observation to clear questions, competing ideas, and evidence that could support or reject each idea.

Skill for Claude Code

Written for Claude Code: allowed-tools in frontmatter.

Good fit Use it to formulate hypotheses, design experiments, compare mechanisms, make predictions, and plan scientific studies.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/foryourhealth111-pixel/vibe-skills/hypothesis-generation
About the project

Vibe-Skills is a collection and routing system that helps AI agents discover, select, and coordinate specialized skills for completing tasks. It is intended for agents that need to organize workflows across many installed capabilities. The catalogue entries are skills and an agent belonging to this system.

foryourhealth111-pixel/Vibe-Skills · 3,252 stars · on GitHub

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add foryourhealth111-pixel/Vibe-Skills --skill hypothesis-generation
Clone the repo
git clone --depth 1 https://github.com/foryourhealth111-pixel/Vibe-Skills

Made for: Claude Code.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for hypothesis-generation

README.md
[![agentmods](https://agentmods.dev/badge/skills/foryourhealth111-pixel/vibe-skills/hypothesis-generation/github.svg)](https://agentmods.dev/skills/foryourhealth111-pixel/vibe-skills/hypothesis-generation)
Your own site
<a href="https://agentmods.dev/skills/foryourhealth111-pixel/vibe-skills/hypothesis-generation"><img src="https://agentmods.dev/badge/skills/foryourhealth111-pixel/vibe-skills/hypothesis-generation/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for hypothesis-generation

Your own site · 80×15
<a href="https://agentmods.dev/skills/foryourhealth111-pixel/vibe-skills/hypothesis-generation"><img src="https://agentmods.dev/badge/skills/foryourhealth111-pixel/vibe-skills/hypothesis-generation.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 73 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 2,539 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin 83% copy Near-identical to another mod in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00073 $0.02539
Opus 5 $0.00036 $0.01269
Sonnet 5 $0.00015 $0.00508
Haiku 4.5 $0.00007 $0.00254

Measured 9d ago against content hash 17739ba3f71f, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-12, from the pricing page.

Security

Grade A, and why

hypothesis-generation scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 9d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

Origin

This is a copy

83% identical to hypothesis-generation — 54 lines differ, which has more behind it and is treated as the original. This page carries a canonical link to it rather than competing with it.

bundled/skills/hypothesis-generation/SKILL.md · 268 lines

How it starts

The opening of the file, as written. The whole thing — 268 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Scientific Hypothesis Generation

Overview

Hypothesis generation is a systematic process for developing testable explanations. Formulate evidence-based hypotheses from observations, design experiments, explore competing explanations, and develop predictions. Apply this skill for scientific inquiry across domains.

When to Use This Skill

This skill should be used when:

  • Developing hypotheses from observations or preliminary data
  • Designing experiments to test scientific questions
  • Exploring competing explanations for phenomena
  • Formulating testable predictions for research
  • Conducting literature-based hypothesis generation
  • Running a lightweight HypoGeniC-style workflow when the user explicitly asks for automated hypothesis generation/testing
  • Planning mechanistic studies across scientific domains

Outputs

Produce a structured hypothesis report when useful:

  • Core observation or anomaly to explain
  • Competing mechanistic hypotheses
  • Testable predictions for each hypothesis
  • Minimal validation experiments or studies
  • Decision criteria for supporting, revising, or rejecting each hypothesis

Figures or diagrams may be included when they clarify the hypothesis structure, but this skill does not require a second skill or helper expert to create them.


Workflow

Follow this systematic process to generate robust scientific hypotheses:

1. Understand the Phenomenon

Start by clarifying the observation, question, or phenomenon that requires explanation:

  • Identify the core observation or pattern that needs explanation
  • Define the scope and boundaries of the phenomenon
  • Note any constraints or specific contexts
  • Clarify what is already known vs. what is uncertain
  • Identify the relevant scientific domain(s)

2. Conduct Comprehensive Literature Search

Search existing scientific literature to ground hypotheses in current evidence. Use both PubMed (for biomedical topics) and general web search (for broader scientific domains):

For biomedical topics:

  • Use WebFetch with PubMed URLs to access relevant literature
  • Search for recent reviews, meta-analyses, and primary research
  • Look for similar phenomena, related mechanisms, or analogous systems

Read the full file on GitHub · 268 lines

Files

What ships with it

6 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 9d ago First seen · 268 lines · 73 tokens per session scan A 17739ba3f71f

Subscribe to this mod's changes

hypothesis-generation is a skill published in the GitHub repository foryourhealth111-pixel/Vibe-Skills (3,252 stars, last pushed 12d ago), licensed Apache-2.0. It adds 73 tokens to every session and 2,539 once invoked, about $0.0004 per session on Opus 5. A static security scan graded it A with 0 findings. It is 83% identical to hypothesis-generation, differing in 54 lines, and is treated as a copy.

Related

Other skills, from other repositories

data-scientist

Data science across machine learning, statistical modeling, and experimentation. Use when selecting ML algorithms, engineering features, designing A/B tests, evaluating model performance, or building predictive pipelines.

borghei/Claude-Skills · 40 tokens

statistical-analyst

Applied statistics for business and product questions — test selection, assumption checks, power planning, effect sizes with intervals, multiplicity correction. Use when interpreting an experiment, sizing a study, or vetting a claim.

borghei/Claude-Skills · 48 tokens

jupyter-live-kernel

Use a live Jupyter kernel for stateful, iterative Python execution via hamelnb. Load this skill when the task involves exploration, iteration, or inspecting intermediate results — data science, ML experimentation, API exploration, or building up complex code step-by-step. Uses terminal to run CLI commands against a…

braxtonROSE4/zorro-agent · 76 tokens

neuroskill-bci

Connect to a running NeuroSkill instance and incorporate the user's real-time cognitive and emotional state (focus, relaxation, mood, cognitive load, drowsiness, heart rate, HRV, sleep staging, and 40+ derived EXG scores) into responses. Requires a BCI wearable (Muse 2/S or OpenBCI) and the NeuroSkill desktop app…

braxtonROSE4/zorro-agent · 82 tokens

sparse-autoencoder-training

Provides guidance for training and analyzing Sparse Autoencoders (SAEs) using SAELens to decompose neural network activations into interpretable features. Use when discovering interpretable features, analyzing superposition, or studying monosemantic representations in language models.

braxtonROSE4/zorro-agent · 58 tokens

research-paper-writing

End-to-end pipeline for writing ML/AI research papers — from experiment design through analysis, drafting, revision, and submission. Covers NeurIPS, ICML, ICLR, ACL, AAAI, COLM. Integrates automated experiment monitoring, statistical analysis, iterative writing, and citation verification.

braxtonROSE4/zorro-agent · 64 tokens