adme-property-predictor

adme-property-predictor is a skill for Claude Code from LeoYeAI/openclaw-master-skills. It costs 61 tokens per session (5,626 once invoked), scanned A, original, MIT.

A drug-discovery tool that predicts ADME properties: how a candidate drug is absorbed, distributed, metabolized, and excreted. It also estimates drug-likeness and pharmacokinetic risks from molecular structure.

In plain words
What is it for?
Use it to screen compound libraries, rank lead candidates, find structural liabilities, and compare chemical analogs.
Why use it?
It helps researchers filter and compare compounds before spending time and money on synthesis or testing.

Skill for Claude Code

Written for Claude Code: allowed-tools in frontmatter.

Good fit Use it to screen compound libraries, rank lead candidates, find structural liabilities, and compare chemical analogs.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/leoyeai/openclaw-master-skills/adme-property-predictor
About the project

OpenClaw Master Skills is a curated, regularly updated collection of skills that extends an AI personal assistant platform with capabilities such as research, browser automation, presentation creation, and prompt work. It is intended for people using OpenClaw or MyClaw.ai to give their agents additional tasks and workflows. The catalogue contains many skills and agents from this collection.

LeoYeAI/openclaw-master-skills · 2,141 stars · on GitHub · myclaw.ai

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add LeoYeAI/openclaw-master-skills --skill adme-property-predictor
Clone the repo
git clone --depth 1 https://github.com/LeoYeAI/openclaw-master-skills

Made for: Claude Code.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for adme-property-predictor

README.md
[![agentmods](https://agentmods.dev/badge/skills/leoyeai/openclaw-master-skills/adme-property-predictor/github.svg)](https://agentmods.dev/skills/leoyeai/openclaw-master-skills/adme-property-predictor)
Your own site
<a href="https://agentmods.dev/skills/leoyeai/openclaw-master-skills/adme-property-predictor"><img src="https://agentmods.dev/badge/skills/leoyeai/openclaw-master-skills/adme-property-predictor/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for adme-property-predictor

Your own site · 80×15
<a href="https://agentmods.dev/skills/leoyeai/openclaw-master-skills/adme-property-predictor"><img src="https://agentmods.dev/badge/skills/leoyeai/openclaw-master-skills/adme-property-predictor.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 61 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 5,626 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector warn 7 Sept 2026
SkillSpector: 1 finding, up to medium

These are SkillSpector’s own severities. On a checked sample its high-severity flags on skills were ~96% false positives — a documented command, a public API, a “never do X” rule — so we show them as a caution to read, not a verdict. Why →

  • medium analysis-evasion · line 1
    Suspicious Unicode normalization or mixed-script content
    Fix: Review the flagged content for security risks. Ensure no credentials, secrets, or sensitive data are exposed.
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00061 $0.05626
Opus 5 $0.00030 $0.02813
Sonnet 5 $0.00012 $0.01125
Haiku 4.5 $0.00006 $0.00563

Measured 8d ago against content hash 569bf79f213d, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-11, from the pricing page.

Security

Grade A, and why

adme-property-predictor scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 8d ago.

The scan reads SKILL.md. This mod also ships 1 executable file (scripts/main.py), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/adme-property-predictor/SKILL.md · 601 lines

How it starts

The opening of the file, as written. The whole thing — 601 lines — stays where its author put it; the contents beside it link to each section on GitHub.

ADME Property Predictor

Overview

Comprehensive pharmacokinetic prediction tool that assesses drug-likeness and ADME properties of small molecules using validated cheminformatics models, molecular descriptors, and structure-property relationships.

Key Capabilities:

  • Multi-Property Prediction: Absorption, Distribution, Metabolism, Excretion
  • Drug-Likeness Scoring: Lipinski's Rule of 5, Veber rules, QED score
  • Batch Processing: Analyze compound libraries efficiently
  • Structure-Based Insights: Identify liability hotspots and optimization opportunities
  • Comparative Analysis: Rank candidates by predicted PK profile

When to Use

✅ Use this skill when:

  • Screening compound libraries for drug-like properties in early discovery
  • Prioritizing lead compounds for advancement based on predicted PK
  • Identifying ADME liabilities requiring structural optimization
  • Comparing analogs to select candidates with optimal ADME profiles
  • Filtering virtual screening hits before synthesis
  • Generating ADME data for regulatory pre-submission packages
  • Teaching pharmacokinetics and drug design principles

❌ Do NOT use when:

  • Exact PK parameters needed for dosing → Use experimental PK studies
  • Biologics (antibodies, proteins) → Use antibody-pk-predictor
  • Natural products with complex structures → Models trained on synthetic small molecules
  • Prodrugs requiring metabolic activation → Use prodrug-activation-predictor
  • Prediction for clinical dosing decisions → CRITICAL: Experimental validation required
  • Assessing toxicity or safety → Use toxicity-structure-alert or admetox-predictor

Related Skills:

  • 上游: chemical-structure-converter (structure preparation), lipinski-rule-filter (rule-based filtering)
  • 下游: drug-candidate-evaluator (integrated scoring), molecular-dynamics-sim (detailed binding)

Integration with Other Skills

Upstream Skills:

  • chemical-structure-converter: Convert between SMILES, InChI, MOL formats
  • lipinski-rule-filter: Initial rule-based drug-likeness screening
  • chemical-structure-converter: Generate 3D conformers for structure-based predictions
  • smiles-de-salter: Remove salt counterions before analysis

Read the full file on GitHub · 601 lines

Files

What ships with it

3 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 8d ago First seen · 601 lines · 61 tokens per session scan A 569bf79f213d

Subscribe to this mod's changes

adme-property-predictor is a skill published in the GitHub repository LeoYeAI/openclaw-master-skills (2,141 stars, last pushed 1mo ago), licensed MIT. It adds 61 tokens to every session and 5,626 once invoked, about $0.0003 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.

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