FridrichMethod/awesome-skills

Curated, auto-synced collection of 2,000+ Claude Code & Codex skills for AI4Protein, bioinformatics, AI development, and academic paper writing. One curl command installs them all.

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200Mods indexed here, across every type
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FridrichMethod/awesome-skills

Skill Claude CodeCodex

Implement proven backend architecture patterns including Clean Architecture, Hexagonal Architecture, and Domain-Driven Design. Use this skill when designing clean architecture for a new microservice, when refactoring a monolith to use bounded contexts, when implementing hexagonal or onion architecture patterns, or…

not rated 15 +1 4d ago A 65 tokens

archs4-database

74

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Query ARCHS4 REST API for uniformly processed RNA-seq expression, tissue patterns, co-expression across 1M+ human/mouse samples. Retrieve z-scores, co-expressed genes, samples by metadata, HDF5 matrices. For variant population genetics use gnomad-database; for pathway enrichment use gget-genomic-databases (Enrichr).

not rated 15 +1 4d ago A 81 tokens

FridrichMethod/awesome-skills

Skill Claude Code

AI-powered design of armored CAR-T cells with cytokine/chemokine expression for enhanced solid tumor efficacy, including IL-12, IL-15, IL-18, and IL-7 armoring strategies.

not rated 15 +1 4d ago A 49 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Turns raw Illumina Infinium methylation BeadChip IDATs (450K, EPIC, EPICv2) into a defensible beta/M matrix with sesame (openSesame/SigDF) or minfi (RGChannelSet -> MethylSet -> GenomicRatioSet). Covers Type I vs Type II probe chemistry and why raw Type II beta is compressed, the signal-to-beta math (beta =…

not rated 15 +1 4d ago A 251 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Performs probe filtering and sample-level QC on Illumina Infinium methylation arrays (450K / EPIC / EPICv2) to decide which probes and samples to trust. Drops detection-p-failed and low-bead-count probes, removes cross-reactive/non-specific probes (Chen 2013 / Pidsley 2016 lists via maxprobes), excludes…

not rated 15 +1 4d ago A 250 tokens

article-writing

78

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Write articles, guides, blog posts, tutorials, newsletter issues, and other long-form content in a distinctive voice derived from supplied examples or brand guidance. Use when the user wants polished written content longer than a paragraph, especially when voice consistency, structure, and credibility matter.

not rated 15 +1 4d ago A 57 tokens

arxiv-database

79

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Search and retrieve preprints from arXiv via the Atom API. Use this skill when searching for papers in physics, mathematics, computer science, quantitative biology, quantitative finance, statistics, electrical engineering, or economics by keywords, authors, arXiv IDs, date ranges, or categories.

not rated 15 +1 4d ago A 63 tokens

arxiv-search

80

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Search arXiv physics, math, and computer science preprints using natural language queries. Powered by Valyu semantic search.

not rated 15 +1 4d ago B 29 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Decides whether and how to polish a draft genome assembly to raise consensus accuracy (QV) with read-type-matched tools - Racon and medaka (ONT consensus), dorado polish, Polypolish and pypolca (Illumina, repeat-aware), Pilon (legacy short-read), NextPolish/NextPolish2, Hapo-G (haplotype-aware), ntEdit, and…

not rated 15 +1 4d ago A 190 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Evaluates genome assembly quality across the three orthogonal axes - contiguity (QUAST auN/NG50/NGx, not bare N50), completeness (BUSCO/compleasm gene-space plus Merqury k-mer completeness), and correctness (reference-free Merqury QV, Inspector/CRAQ structural errors, asmgene false-duplication/collapse). Covers why…

not rated 15 +1 4d ago A 166 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Single-variant common-variant GWAS with plink2 --glm (linear/logistic, Firth) and the linear mixed models GEMMA, BOLT-LMM, SAIGE, regenie (SPA). A GWAS statistic is valid only when genotype is independent of unmodeled phenotype drivers after the chosen covariates and random effects, so the engine follows sample…

not rated 15 +1 4d ago A 239 tokens

astropy-astronomy

84

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Core Python library for astronomy/astrophysics: units with dimensional analysis, celestial coordinate transforms (ICRS/Galactic/AltAz/FK5), FITS I/O, tables (FITS/HDF5/VOTable/CSV), cosmology (Planck18, distance/age), precise time (UTC/TAI/TT/TDB, Julian, barycentric), WCS pixel-world mapping, model fitting. For…

not rated 15 +1 4d ago A 108 tokens

astropy

85

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Core Python library for astronomy and astrophysics workflows that need Astropy APIs, including units/quantities, coordinates, FITS I/O, tables, time systems, WCS, and cosmology. Use when implementing or debugging astronomical data analysis code with Astropy.

not rated 15 +1 changed 2d ago A 56 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Master Python asyncio, concurrent programming, and async/await patterns for high-performance applications. Use when building async APIs, concurrent systems, or I/O-bound applications requiring non-blocking operations.

not rated 15 +1 4d ago A 42 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Call accessible chromatin regions from ATAC-seq BAM files using MACS3, MACS2, Genrich, or HMMRATAC. Use when identifying open chromatin from aligned ATAC-seq, choosing between point-source vs HMM peak callers, applying ENCODE-style pseudoreplicate IDR, removing blacklist regions, or fixing 501bp consensus peaks for…

not rated 15 +1 4d ago A 93 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

ATAC-seq library quality control -- TSS enrichment, FRiP, fragment-size periodicity, library complexity (NRF/PBC1/PBC2), mitochondrial fraction, and ENCODE 4 thresholds. Use when assessing whether an ATAC-seq library passes ENCODE acceptance criteria, diagnosing transposition artefacts, comparing Omni-ATAC vs standard…

not rated 15 +1 4d ago A 96 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Orchestrates the end-to-end bulk ATAC-seq pipeline from FASTQ to differential accessibility and TF footprints, chaining Nextera-aware fastp QC, Bowtie2 alignment, chrM removal, dedup, a single Tn5 +4/-5 shift, MACS3 peak calling, Corces fixed-width consensus, DiffBind/csaw differential accessibility, and TOBIAS…

not rated 15 +1 4d ago A 194 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Maps query single-cell data onto reference atlases and transfers cell-type labels using scArches surgery (scVI/scANVI), Symphony, Azimuth, CellTypist, scPoli, popV, and foundation models, with explicit out-of-distribution and label-transfer uncertainty. Use when annotating new single-cell datasets against a…

not rated 15 +1 4d ago A 122 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Build comprehensive attack trees to visualize threat paths. Use when mapping attack scenarios, identifying defense gaps, or communicating security risks to stakeholders.

not rated 15 +1 4d ago A 31 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Master authentication and authorization patterns including JWT, OAuth2, session management, and RBAC to build secure, scalable access control systems. Use when implementing auth systems, securing APIs, or debugging security issues.

not rated 15 +1 4d ago A 46 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Molecular docking with AutoDock Vina (Python API). Receptor/ligand prep (Meeko + RDKit), grid box, docking, pose and binding energy analysis, and batch virtual screening.

not rated 15 +1 4d ago A 49 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Aggregates per-tool QC metrics (FastQC, fastp, alignment, quantification, variant calling, single-cell) into one interactive MultiQC report, and guides module scoping, sample-name resolution, large-cohort behavior, and turning the report into an actual QC gate. Use when summarizing QC across many samples, building a…

not rated 15 +1 4d ago A 91 tokens

autonomous-loops

95

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Patterns and architectures for autonomous Claude Code loops — from simple sequential pipelines to RFC-driven multi-agent DAG systems.

not rated 15 +1 4d ago A 26 tokens

FridrichMethod/awesome-skills

Skill Claude Code

Skill "autonomous-oncology-agent" from FridrichMethod/awesome-skills, covering copyright notice, copyright (c) 2026 md babu mia, phd, all rights reserved, this code is proprietary and confidential and provenance: authenticated by md babu mia.

not rated 15 +1 4d ago A 8 tokens

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