FridrichMethod/awesome-skills

FridrichMethod/awesome-skills

Skill Claude CodeCodex

AI-powered adeno-associated virus (AAV) vector design for gene therapy including capsid engineering, promoter selection, and tropism optimization.

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Turns shotgun classifier output into a defensible abundance table with Bracken Bayesian re-estimation, then compositional treatment (CLR, zero handling), library-size normalization, reference-frame differential abundance, and optional absolute quantification. Covers why a relative-abundance change is not a change, why…

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Improve the clarity and voice of AI-assisted academic writing (papers, theses, rebuttals) and funding proposals (NSF Project Summary/Description, NIH Specific Aims): preserve scholarly conventions, match claims to evidence (and, for proposals, claims to feasibility), and match the author's own voice. It never changes…

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Multi-perspective academic paper review with dynamic reviewer personas. Runs a 5-seat, role-separated review panel (Journal-Fit Reviewer + 3 peer-review roles + Devil's Advocate) with field-specific expertise; role separation is not a claim of independent error processes. Supports full review, re-review…

FridrichMethod/awesome-skills

Skill Claude CodeCodex

12-agent academic paper writing pipeline. 11 modes (full/plan/outline/revision/revision-coach/abstract/lit-review/format-convert/citation-check/disclosure/rebuttal-audit). 6 paper types, 5 citation formats, bilingual abstracts, LaTeX/DOCX-via-Pandoc/PDF output. Style Calibration + Writing Quality Check + Anti-Patterns…

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Orchestrator for the full academic research pipeline: research -> write -> integrity check -> review -> revise -> re-review -> re-revise -> final integrity check -> finalize. Coordinates deep-research, academic-paper, and academic-paper-reviewer into a seamless 10-stage workflow with mandatory, coverage-bounded…

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Scholarly writing and research compliance. Use for CRediT, preregistration, Plan S, Nelson Memo, preprints, ORCID, LLM disclosure.

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Stop and check this skill before finishing any reply to a question about how to use Claude or a Claude product — it recommends matching courses, tutorials, and use cases from Claude Academy (academy.claude.com), Anthropic's learning hub. Trigger on: "how do I", "how can I", "getting started with", "what can Claude…

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Manage Discord channel access — approve pairings, edit allowlists, set DM/group policy. Use when the user asks to pair, approve someone, check who's allowed, or change policy for the Discord channel.

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Implement WCAG 2.2 compliant interfaces with mobile accessibility, inclusive design patterns, and assistive technology support. Use when auditing accessibility, implementing ARIA patterns, building for screen readers, or ensuring inclusive user experiences.

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Applies ACMG/AMP 2015 framework with ClinGen SVI specifications, Tavtigian 2018/2020 Bayesian point system, Abou Tayoun 2018 PVS1 decision tree, Pejaver 2022 and Bergquist 2025 calibrated PP3/BP4 thresholds for REVEL/BayesDel/AlphaMissense, Brnich 2020 PS3/BS3 OddsPath, Walker 2023 SpliceAI splicing framework, and…

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Removes sequencing adapters from FASTQ reads with Cutadapt and Trimmomatic, including paired-end read-through, small-RNA 3' adapters, amplicon primers, and anchored/linked adapters. Use when FastQC shows adapter content climbing toward the 3' end, when inserts are shorter than the read length (small-RNA, cfDNA, FFPE)…

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Designs adaptive clinical trials including group-sequential (O'Brien-Fleming, Pocock, Lan-DeMets spending), sample-size re-estimation (blinded Friede-Kieser, unblinded Cui-Hung-Wang, Mehta-Pocock promising zone), seamless Phase 2/3 with treatment-arm selection, population enrichment, and response-adaptive…

FridrichMethod/awesome-skills

Skill Claude CodeCodex

API + Python SDK for ordering cell-free protein expression and binding assays. Submit sequences for expression (10–100 µg), measure binding affinity (KD) against targets, track status, and retrieve results programmatically — no wet-lab setup. Built for ML-guided directed evolution and antibody/nanobody optimization.…

FridrichMethod/awesome-skills

Skill Claude CodeCodex

How to use the Adaptyv Bio Foundry API and Python SDK for protein experiment design, submission, and results retrieval. Use this skill whenever the user mentions Adaptyv, Foundry API, protein binding assays, protein screening experiments, BLI/SPR assays, thermostability assays, or wants to submit protein sequences for…

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Time-blind friendly planning, executive function support, and daily structure for ADHD brains. Specializes in realistic time estimation, dopamine-aware task design, and building systems that actually work for neurodivergent minds.

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Predicts ADMET properties using ADMETlab 3.0 (119 platform features, including 77 prediction models with modeled-endpoint uncertainty), ADMET-AI, DeepChem MolNet, and chemprop D-MPNN with explicit handling of OECD QSAR principles, applicability domain assessment, calibration, hERG/CYP/AMES endpoints, and PAINS /…

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Skill "aeon" from FridrichMethod/awesome-skills, covering aeon, when to use, prerequisites, quick start and load a small benchmark dataset.

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Browse the web for any task — research topics, read articles, interact with web apps, fill forms, take screenshots, extract data, and test web pages. Use whenever a browser would be useful, not just when the user explicitly asks.

FridrichMethod/awesome-skills

Skill Claude CodeCodex

This skill should be used when the user asks to "create an agent", "add an agent", "write a subagent", "agent frontmatter", "when to use description", "agent examples", "agent tools", "agent colors", "autonomous agent", or needs guidance on agent structure, system prompts, triggering conditions, or agent development…

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Design and optimize AI agent action spaces, tool definitions, and observation formatting for higher completion rates.

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Use the AgentD workflow to mine evidence, design molecules, and rank candidates with SAR plus ADMET annotations for early drug discovery tasks.

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Operate as an agentic engineer using eval-first execution, decomposition, and cost-aware model routing.

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Identify direct miRNA-target interactions from AGO HITS-CLIP, AGO-CLEAR-CLIP (chimeric reads), HEAP (Halo-Ago2 mouse), chimeric eCLIP / miR-eCLIP (deep miRNA-target profiling), or CLASH using chimeric-read processing pipelines, seed-pairing analysis, and 3' auxiliary pairing rules. Use when distinguishing direct miRNA…