bio-data-visualization-dimensionality-reduction-plots

bio-data-visualization-dimensionality-reduction-plots is a skill for Claude Code, Codex from GPTomics/bioSkills. It costs 133 tokens per session (4,972 once invoked), scanned A, original, MIT.

A guide to reducing high-dimensional data to two-dimensional plots with PCA, t-SNE, UMAP, or PHATE. These methods turn many measurements per item into a map, but the map does not preserve every distance or relationship.

In plain words
What is it for?
Use it to explore omics datasets, compare groups, inspect neighborhoods, or examine continuous biological transitions.
Why use it?
It helps choose a method for the pattern you want to inspect and limits over-interpretation of 2D plots.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to explore omics datasets, compare groups, inspect neighborhoods, or examine continuous biological transitions.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/gptomics/bioskills/dimensionality-reduction-plots
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add GPTomics/bioSkills --skill dimensionality-reduction-plots
Clone the repo
git clone --depth 1 https://github.com/GPTomics/bioSkills

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for bio-data-visualization-dimensionality-reduction-plots

README.md
[![agentmods](https://agentmods.dev/badge/skills/gptomics/bioskills/dimensionality-reduction-plots/github.svg)](https://agentmods.dev/skills/gptomics/bioskills/dimensionality-reduction-plots)
Your own site
<a href="https://agentmods.dev/skills/gptomics/bioskills/dimensionality-reduction-plots"><img src="https://agentmods.dev/badge/skills/gptomics/bioskills/dimensionality-reduction-plots/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for bio-data-visualization-dimensionality-reduction-plots

Your own site · 80×15
<a href="https://agentmods.dev/skills/gptomics/bioskills/dimensionality-reduction-plots"><img src="https://agentmods.dev/badge/skills/gptomics/bioskills/dimensionality-reduction-plots.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 133 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 4,972 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00133 $0.04972
Opus 5 $0.00067 $0.02486
Sonnet 5 $0.00027 $0.00994
Haiku 4.5 $0.00013 $0.00497

Measured 8d ago against content hash 8776925949ca, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-12, from the pricing page.

Security

Grade A, and why

bio-data-visualization-dimensionality-reduction-plots scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 8d ago.

The scan reads SKILL.md. This mod also ships 1 executable file (examples/embedding_phd.py), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

Origin

Copies of this mod

1 near-identical copy found in the catalogue:

data-visualization/dimensionality-reduction-plots/SKILL.md · 327 lines

How it starts

The opening of the file, as written. The whole thing — 327 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Version Compatibility

Reference examples tested with: scanpy 1.10+, anndata 0.10+, scikit-learn 1.4+, umap-learn 0.5+, openTSNE 1.0+, phate 1.0+, ggplot2 3.5+, PCAtools 2.16+, matplotlib 3.8+.

Before using code patterns, verify installed versions match. If versions differ:

  • Python: pip show <package> then help(module.function) to check signatures
  • R: packageVersion('<pkg>') then ?function_name to verify parameters

If code throws ImportError, AttributeError, or TypeError, introspect the installed package and adapt the example to match the actual API rather than retrying.

Dimensionality-Reduction Plots

"Make a PCA / UMAP / t-SNE plot" -> Choose a projection method aligned with what the plot must reveal — variance explained (PCA), local neighborhood structure (t-SNE), manifold approximation with some global structure (UMAP), or continuous transitions (PHATE). Set hyperparameters deliberately. Communicate the projection's limits and refuse to over-interpret 2D distances.

  • Python: sklearn.decomposition.PCA, openTSNE, umap-learn, phate, scanpy.tl.umap / scanpy.tl.tsne / scanpy.tl.pca
  • R: prcomp, PCAtools::pca, Seurat::RunPCA / RunUMAP / RunTSNE, phateR

The Single Most Important Modern Insight -- 2D Embeddings Distort

Chari & Pachter 2023 PLOS Comp Biol 19:e1011288 demonstrated that 2D embeddings of single-cell data lose >95% of the high-dimensional geometry — local neighborhoods are preserved by construction, but distances between distant cells, density estimates, and global topology are NOT preserved. The "specious art" of single-cell genomics is the practice of reading 2D layout as biology.

Practical consequence: a UMAP plot communicates "these cells are similar locally" and nothing more. Distance between clusters is meaningless. Density of points within a cluster is dominated by the embedding's repulsion parameter, not the underlying biology. A trajectory inferred from "the gap" between two clusters in UMAP space is an artifact unless validated against the high-dimensional data (RNA velocity, diffusion pseudotime, PHATE).

Read the full file on GitHub · 327 lines

Files

What ships with it

2 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 8d ago First seen · 327 lines · 133 tokens per session scan A 8776925949ca

Subscribe to this mod's changes

bio-data-visualization-dimensionality-reduction-plots is a skill published in the GitHub repository GPTomics/bioSkills (1,201 stars, last pushed 27d ago), licensed MIT. It adds 133 tokens to every session and 4,972 once invoked, about $0.0007 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.

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