bio-geo-data

bio-geo-data is a skill for Claude Code, Codex from GPTomics/bioSkills. It costs 141 tokens per session (4,703 once invoked), scanned A, original, MIT.

A tool for finding and downloading gene-expression studies from GEO, a public NCBI archive of biological experiment data, and its European mirror.

In plain words
What is it for?
Use it to locate expression datasets and choose between processed data, such as a normalized table, and the original supplementary or sequencing files.
Why use it?
It helps you handle complex studies correctly, including collections that contain several smaller studies or different measurement technologies.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to locate expression datasets and choose between processed data, such as a normalized table, and the original supplementary or sequencing files.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/gptomics/bioskills/geo-data
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add GPTomics/bioSkills --skill geo-data
Clone the repo
git clone --depth 1 https://github.com/GPTomics/bioSkills

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for bio-geo-data

README.md
[![agentmods](https://agentmods.dev/badge/skills/gptomics/bioskills/geo-data/github.svg)](https://agentmods.dev/skills/gptomics/bioskills/geo-data)
Your own site
<a href="https://agentmods.dev/skills/gptomics/bioskills/geo-data"><img src="https://agentmods.dev/badge/skills/gptomics/bioskills/geo-data/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for bio-geo-data

Your own site · 80×15
<a href="https://agentmods.dev/skills/gptomics/bioskills/geo-data"><img src="https://agentmods.dev/badge/skills/gptomics/bioskills/geo-data.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 141 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 4,703 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 1 finding. A grade says what 26 rules found in the file — not that it is safe.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00141 $0.04703
Opus 5 $0.00071 $0.02351
Sonnet 5 $0.00028 $0.00941
Haiku 4.5 $0.00014 $0.00470

Measured 8d ago against content hash ad08b4ee41bc, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-12, from the pricing page.

Security

Grade A, and why

bio-geo-data scanned grade A with 1 finding against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 8d ago.

The scan reads SKILL.md. This mod also ships 3 executable files (examples/geo_from_pubmed.py, examples/geo_to_sra.py, examples/search_geo.py), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Makes network callslowCapability

Not a fault in itself. Listed so you know the mod talks to something, and to what.

- CLI: `wget` from `ftp.ncbi.nlm.nih.gov/geo/series/...`
Origin

Copies of this mod

1 near-identical copy found in the catalogue:

database-access/geo-data/SKILL.md · 373 lines

How it starts

The opening of the file, as written. The whole thing — 373 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Version Compatibility

Reference examples tested with: BioPython 1.83+, GEOparse 2.0+, R Bioconductor GEOquery 2.70+, pandas 2.2+

Before using code patterns, verify installed versions match. If versions differ:

  • Python: pip show biopython geoparse then introspect signatures
  • R: packageVersion('GEOquery')

If the GSE structure doesn't match expectations (missing fields, malformed series matrix), re-fetch from FTP directly and inspect the SOFT or MINiML file as source of truth.

GEO Data

"Pull expression data from GEO accession GSE..." -> GEO stores Series (GSE), Samples (GSM), Platforms (GPL), and curated DataSets (GDS, frozen 2018). The single most consequential decision is processed (series matrix) vs raw (supplementary files / linked SRA) — the answer turns on how much trust the submitter's normalization deserves.

The single most-missed gotcha: SuperSeries. A GSE may be a meta-container (!Series_relation = SuperSeries of: GSExxxxx) holding multiple sub-studies on different platforms. Naively pulling samples from a SuperSeries gives mixed Affymetrix + Illumina + RNA-seq, mis-batched.

  • Python: Entrez.esearch(db='gds'), GEOparse for full series download
  • R: GEOquery::getGEO() (Bioconductor; more mature than GEOparse)
  • CLI: wget from ftp.ncbi.nlm.nih.gov/geo/series/...

Required Setup

pip install biopython GEOparse pandas
# OR for R-side:
# R: BiocManager::install('GEOquery')
from Bio import Entrez
Entrez.email = '[email protected]'
Entrez.api_key = 'optional'

GEO record taxonomy

Prefix Type Granularity What's in it
GSE Series One study Title, summary, design, links to GSMs, supplementary files
GSM Sample One biological/technical sample Submitter metadata, per-sample processed data, link to raw SRA
GPL Platform One array / sequencer Probe annotations or sequencer model
GDS DataSet Curated, normalized subset of one GSE Re-normalized expression matrix (frozen 2018; new GDS no longer created)
GSEXXX SuperSeries Series meta-container Wraps multiple SubSeries !Series_relation = SuperSeries of: ...

Read the full file on GitHub · 373 lines

Files

What ships with it

4 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 8d ago First seen · 373 lines · 141 tokens per session scan A ad08b4ee41bc

Subscribe to this mod's changes

bio-geo-data is a skill published in the GitHub repository GPTomics/bioSkills (1,201 stars, last pushed 27d ago), licensed MIT. It adds 141 tokens to every session and 4,703 once invoked, about $0.0007 per session on Opus 5. A static security scan graded it A with 1 finding (makes network calls). No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.

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