evo2

evo2 is a skill for Claude Code, Codex from HughYau/AcademicForge. It costs 83 tokens per session (1,482 once invoked), scanned A, original, no licence file.

A DNA-sequence model for scoring, representing, and generating long stretches of genomic sequence. It can calculate likelihoods, create embeddings, generate DNA from a prefix, and score variants.

In plain words
What is it for?
Use it for variant-effect scoring, genomic-window embeddings, DNA generation conditioned on a prefix, and other sequence-scoring tasks.
Why use it?
It helps assess how plausible a sequence or mutation is and provides numerical inputs for later genomic classification tasks.

Skill for Claude CodeCodex

Which agent this was written for is unclear — body not stored (licence); the path alone says nothing.

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

agentmods
npx agentmods add skills/hughyau/academicforge/evo2
Any agent
npx skills add HughYau/AcademicForge --skill evo2
Clone the repo
git clone --depth 1 https://github.com/HughYau/AcademicForge

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for evo2

README.md
[![agentmods](https://agentmods.dev/badge/skills/hughyau/academicforge/evo2.svg)](https://agentmods.dev/skills/hughyau/academicforge/evo2)
Your own site
<a href="https://agentmods.dev/skills/hughyau/academicforge/evo2"><img src="https://agentmods.dev/badge/skills/hughyau/academicforge/evo2.svg" alt="Measured on agentmods" height="20"></a>
Per session 83 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,482 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. Scan, not verified.
Origin unknown No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00083 $0.01482
Opus 5 $0.00042 $0.00741
Sonnet 5 $0.00017 $0.00296
Haiku 4.5 $0.00008 $0.00148

Measured 6d ago against content hash fe8268806919, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-05, from the pricing page.

Security

Grade A, and why

evo2 scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 6d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/claude-science/evo2/SKILL.md · 154 lines

The source is not reproduced here

A licence we could not identify

The repository carries a LICENSE file, but it is custom or dual enough that GitHub cannot name it and neither can this catalogue. Unknown terms are not permission, so the body is not copied here. Read the licence at the source and decide for yourself.

Read it on GitHub

Files

What ships with it

1 file beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 6d ago First seen · 154 lines · 83 tokens per session scan A fe8268806919

Subscribe to this mod's changes

evo2 is a skill published in the GitHub repository HughYau/AcademicForge (2,512 stars, last pushed 6d ago), with no licence file. It adds 83 tokens to every session and 1,482 once invoked, about $0.0004 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

Related

Other skills, from other repositories

esmfold2

Biohub ESMFold2 / ESMFold2-Fast all-atom co-folding (Candido et al. 2026, github.com/Biohub/esm). Single-sequence and MSA modes; protein, DNA, RNA, ligand (CCD/SMILES), modified residues. FoldBench Ab-Ag 50-55%, PPI 70-77% DockQ-pass. Also covers the ESMC-{300M,600M,6B} protein language models from the same release…

aipoch/open-science · 223 tokens

scgpt

Embed and annotate single-cell expression data with scGPT, a foundation model for single-cell biology. Use this skill when: (1) Producing cell embeddings from an AnnData for clustering/integration, (2) Zero-shot or fine-tuned cell-type annotation, (3) Gene-level representation for perturbation/GRN tasks. For…

aipoch/open-science · 89 tokens

evo2

Score, embed, and generate DNA sequences with Evo 2, a long-context genomic foundation model. Use this skill when: (1) Computing per-nucleotide or per-sequence likelihoods for variant effect scoring, (2) Embedding genomic windows for downstream classification, (3) Generating DNA conditioned on a prefix, (4) Scoring…

aipoch/open-science · 83 tokens

iterate-ml-experiment

Owns the iteration loop on top of an ML workspace: the journal/JOURNAL.md index and the per-experiment journal/NNshortname.md design notes that must be drafted and approved by the user before experiments/NNshortname.py is created. Drives the propose → iterate → approve → implement → record loop; dispatches to…

probabl-ai/skills · 422 tokens

iterate-from-user

Source the next ML experiment proposal from the user via one of three entry points selected by AskUserQuestion: (a) a scientific article URL the agent must read and synthesize, (b) a resource link or path (GitHub issue / spec file / reference repo), or (c) free-text the user types directly. In every branch, the agent…

probabl-ai/skills · 401 tokens

iterate-from-skore

Source the next ML experiment proposal by reading the audit digest at scratch/audit/ /audit.md (produced by audit-ml-pipeline at § 4 record-outcome). For every row in the digest's ## Checks summary whose severity is issue or tip, follow the row's documentationurl to draft a Backlog row whose Item is the mitigation the…

probabl-ai/skills · 497 tokens