ligandmpnn

ligandmpnn is a skill for Claude Code, Codex from HughYau/AcademicForge. It costs 100 tokens per session (1,657 once invoked), scanned A, original, no licence file.

A protein-design tool that redesigns amino acids around a known molecular backbone while considering nearby ligands, nucleic acids, or metals. Inverse folding means finding sequences that could produce a chosen structure.

In plain words
What is it for?
Use it to redesign binding pockets, create metal-coordinating sites, and design protein sequences around ligand or nucleic-acid context.
Why use it?
It helps adapt a protein structure to bind a small molecule or cofactor, or to coordinate a metal with the required geometry.

Skill for Claude CodeCodex

Which agent this was written for is unclear — body not stored (licence); the path alone says nothing.

Good fit Use it to redesign binding pockets, create metal-coordinating sites, and design protein sequences around ligand or nucleic-acid context.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/hughyau/academicforge/ligandmpnn
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add HughYau/AcademicForge --skill ligandmpnn
Clone the repo
git clone --depth 1 https://github.com/HughYau/AcademicForge

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for ligandmpnn

README.md
[![agentmods](https://agentmods.dev/badge/skills/hughyau/academicforge/ligandmpnn/github.svg)](https://agentmods.dev/skills/hughyau/academicforge/ligandmpnn)
Your own site
<a href="https://agentmods.dev/skills/hughyau/academicforge/ligandmpnn"><img src="https://agentmods.dev/badge/skills/hughyau/academicforge/ligandmpnn/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for ligandmpnn

Your own site · 80×15
<a href="https://agentmods.dev/skills/hughyau/academicforge/ligandmpnn"><img src="https://agentmods.dev/badge/skills/hughyau/academicforge/ligandmpnn.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 100 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,657 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin unknown No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00100 $0.01657
Opus 5 $0.00050 $0.00829
Sonnet 5 $0.00020 $0.00331
Haiku 4.5 $0.00010 $0.00166

Measured 10d ago against content hash 004f25fe7caa, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-09, from the pricing page.

Security

Grade A, and why

ligandmpnn scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 10d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/claude-science/ligandmpnn/SKILL.md · 124 lines

The source is not reproduced here

A licence we could not identify

The repository carries a LICENSE file, but it is custom or dual enough that GitHub cannot name it and neither can this catalogue. Unknown terms are not permission, so the body is not copied here. Read the licence at the source and decide for yourself.

Read it on GitHub

Files

What ships with it

1 file beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 10d ago First seen · 124 lines · 100 tokens per session scan A 004f25fe7caa

Subscribe to this mod's changes

ligandmpnn is a skill published in the GitHub repository HughYau/AcademicForge (2,527 stars, last pushed 10d ago), with no licence file. It adds 100 tokens to every session and 1,657 once invoked, about $0.0005 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.