pathml

pathml is a skill for Claude Code, Codex from magic3007/dotfiles. It costs 69 tokens per session (1,512 once invoked), scanned A, a copy of pathml, MIT.

A Python toolkit for computational pathology, the use of software and machine learning to analyze medical tissue images. It works with whole-slide images, multiplexed microscopy, tissue structure, and cell-level data.

In plain words
What is it for?
Processing pathology slides, normalizing stains, detecting and classifying nuclei, building tissue graphs, analyzing multiplexed images, training models, and working with large slide datasets.
Why use it?
It brings image loading, preprocessing, cell analysis, spatial analysis, and model training into one pathology workflow.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one. Also seen: mentions Codex.

Good fit Processing pathology slides, normalizing stains, detecting and classifying nuclei, building tissue graphs, analyzing multiplexed images, training models, and working with large slide datasets.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/magic3007/dotfiles/pathml
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add magic3007/dotfiles --skill pathml
Clone the repo
git clone --depth 1 https://github.com/magic3007/dotfiles

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for pathml

README.md
[![agentmods](https://agentmods.dev/badge/skills/magic3007/dotfiles/pathml.svg)](https://agentmods.dev/skills/magic3007/dotfiles/pathml)
Your own site
<a href="https://agentmods.dev/skills/magic3007/dotfiles/pathml"><img src="https://agentmods.dev/badge/skills/magic3007/dotfiles/pathml.svg" alt="Measured on agentmods" height="20"></a>
Per session 69 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,512 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin 94% copy Near-identical to another mod in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00069 $0.01512
Opus 5 $0.00034 $0.00756
Sonnet 5 $0.00014 $0.00302
Haiku 4.5 $0.00007 $0.00151

Measured 4d ago against content hash 6055f86be24b, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-08, from the pricing page.

Security

Grade A, and why

pathml scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 4d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

Origin

This is a copy

94% identical to pathml — 4 lines differ, which has more behind it and is treated as the original. This page carries a canonical link to it rather than competing with it.

claude/skills/scientific-agent-skills/skills/pathml/SKILL.md · 166 lines

How it starts

The opening of the file, as written. The whole thing — 166 lines — stays where its author put it; the contents beside it link to each section on GitHub.

PathML

Overview

PathML is a comprehensive Python toolkit for computational pathology workflows, designed to facilitate machine learning and image analysis for whole-slide pathology images. The framework provides modular, composable tools for loading diverse slide formats, preprocessing images, constructing spatial graphs, training deep learning models, and analyzing multiparametric imaging data from technologies like CODEX and multiplex immunofluorescence.

When to Use This Skill

Apply this skill for:

  • Loading and processing whole-slide images (WSI) in various proprietary formats
  • Preprocessing H&E stained tissue images with stain normalization
  • Nucleus detection, segmentation, and classification workflows
  • Building cell and tissue graphs for spatial analysis
  • Training or deploying machine learning models (HoVer-Net, HACTNet) on pathology data
  • Analyzing multiparametric imaging (CODEX, Vectra, MERFISH) for spatial proteomics
  • Quantifying marker expression from multiplex immunofluorescence
  • Managing large-scale pathology datasets with HDF5 storage
  • Tile-based analysis and stitching operations

Core Capabilities

PathML provides six major capability areas documented in detail within reference files:

1. Image Loading & Formats

Load whole-slide images from 160+ proprietary formats including Aperio SVS, Hamamatsu NDPI, Leica SCN, Zeiss ZVI, DICOM, and OME-TIFF. PathML automatically handles vendor-specific formats and provides unified interfaces for accessing image pyramids, metadata, and regions of interest.

See: references/image_loading.md for supported formats, loading strategies, and working with different slide types.

2. Preprocessing Pipelines

Build modular preprocessing pipelines by composing transforms for image manipulation, quality control, stain normalization, tissue detection, and mask operations. PathML's Pipeline architecture enables reproducible, scalable preprocessing across large datasets.

Key transforms:

  • StainNormalizationHE - Macenko/Vahadane stain normalization
  • TissueDetectionHE, NucleusDetectionHE - Tissue/nucleus segmentation
  • MedianBlur, GaussianBlur - Noise reduction
  • LabelArtifactTileHE - Quality control for artifacts

Read the full file on GitHub · 166 lines

Files

What ships with it

6 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 4d ago First seen · 166 lines · 69 tokens per session scan A 6055f86be24b

Subscribe to this mod's changes

pathml is a skill published in the GitHub repository magic3007/dotfiles (11 stars, last pushed today), licensed MIT. It adds 69 tokens to every session and 1,512 once invoked, about $0.0003 per session on Opus 5. A static security scan graded it A with 0 findings. It is 94% identical to pathml, differing in 4 lines, and is treated as a copy.

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