Getting it into your agent
One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.
npx skills add malekokour/clinpharm-pmx-skills --skill assess-special-population-strategygit clone --depth 1 https://github.com/malekokour/clinpharm-pmx-skillsWrote this? Show the measurements
A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.
[](https://agentmods.dev/skills/malekokour/clinpharm-pmx-skills/assess-special-population-strategy)<a href="https://agentmods.dev/skills/malekokour/clinpharm-pmx-skills/assess-special-population-strategy"><img src="https://agentmods.dev/badge/skills/malekokour/clinpharm-pmx-skills/assess-special-population-strategy/github.svg" alt="Measured on agentmods" height="20"></a>Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.
<a href="https://agentmods.dev/skills/malekokour/clinpharm-pmx-skills/assess-special-population-strategy"><img src="https://agentmods.dev/badge/skills/malekokour/clinpharm-pmx-skills/assess-special-population-strategy.svg" alt="Reviewed on agentmods" width="80" height="20"></a>What it costs to keep this loaded
Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.
| Model | Per session | Once invoked |
|---|---|---|
| Fable 5.1 | $0.00187 | $0.02590 |
| Opus 5 | $0.00093 | $0.01295 |
| Sonnet 5 | $0.00037 | $0.00518 |
| Haiku 4.5 | $0.00019 | $0.00259 |
Grade A, and why
assess-special-population-strategy scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 12d ago.
A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.
Nothing flagged
None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.
How it starts
The opening of the file, as written. The whole thing — 231 lines — stays where its author put it; the contents beside it link to each section on GitHub.
Special Population Strategy Assessment
Assess a programme's special-population evidence strategy for completeness, internal consistency, and traceability to the criteria that create each obligation. Cover renal impairment, hepatic impairment, paediatrics, pregnancy and lactation, elderly, and any other population the programme's scope declares — each mapped to whether it is addressed by a dedicated study, a PopPK covariate analysis, a model-based approach, a written waiver rationale, or nothing.
This skill assesses the strategy. It never decides that a waiver is sufficient, commits to a study, selects a dose for a special population, or determines that characterisation is adequate for filing.
Who this is for
Clinical pharmacology leads owning a programme's special-population strategy · CP reviewers preparing for a pre-NDA or Type C meeting · regulatory strategists checking that the strategy matches what the evidence expectations demand for each population.
When to use this skill
- "Does our special-population strategy cover what a reviewer will expect?"
- "Which populations still need characterisation before we file?"
- "Is our paediatric plan consistent with what we told the agency?"
- "Map every special population to whether we have a study, a PopPK analysis, a waiver, or nothing"
- "Are the renal and hepatic strategies internally consistent with the dose-modification rules?"
When NOT to use this skill
| Request | Why not this skill | Where it belongs |
|---|---|---|
| "Review the renal impairment study report" | One finished study report against its own design and sources | review-csr-pk-consistency |
| "Assess the age, weight and sex covariate effects in the PopPK" | Demographic covariate characterisation within one analysis | assess-demographic-covariate-effects |
| "Assess the pharmacogenomic characterisation" | Genotype-phenotype characterisation | assess-pharmacogenomic-evidence |
| "What studies are missing across the whole CP plan?" | Full programme-level gap assessment across all criteria | assess-development-plan-gaps |
| "Is the hepatic waiver rationale sufficient?" | A judgement about the adequacy of a scientific argument | A qualified clinical pharmacologist |
| "What dose should we use in paediatrics?" | A dose decision | A qualified clinical pharmacologist |
| "Commit to the paediatric study timeline" | A programme commitment | The programme team |
What ships with it
2 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.
What this file has done since we first saw it
Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.
- 12d ago First seen · 231 lines · 187 tokens per session scan A 8e080150891a
assess-special-population-strategy is a skill published in the GitHub repository malekokour/clinpharm-pmx-skills (6 stars, last pushed 11d ago), licensed MIT. It adds 187 tokens to every session and 2,590 once invoked, about $0.0009 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-31.
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