setup-macs3-remote-tool

setup-macs3-remote-tool is a skill for Codex from mims-harvard/ToolUniverse. It costs 42 tokens per session (1,920 once invoked), scanned A, a copy of setup-liana-remote-tool, Apache-2.0.

A setup and validation guide for running MACS3 as a remote ToolUniverse tool. MACS3 identifies peaks in sequencing data, such as DNA regions with unusually strong signal.

In plain words
What is it for?
Use it to deploy or audit MACS3 for peak calling from sequencing alignment data and verify a remote peak-detection call.
Why use it?
It helps you compile the tool, check its service connection and input paths, and troubleshoot temporary-file and resource requirements.

Skill for Codex

Written for Codex: agents/openai.yaml present.

Good fit Use it to deploy or audit MACS3 for peak calling from sequencing alignment data and verify a remote peak-detection call.

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Install with agentmods
npx agentmods add skills/mims-harvard/tooluniverse/setup-macs3-remote-tool
About the project

ToolUniverse is a collection of tools, interfaces, and supporting components for building AI systems that perform scientific work. It is for developers creating AI scientist agents that use APIs, databases, machine-learning tools, and domain-specific utilities. The catalogue includes skills, commands, an MCP server, an agent, and a hook for working with the ecosystem.

mims-harvard/ToolUniverse · 1,680 stars · on GitHub · aiscientist.tools

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add mims-harvard/ToolUniverse --skill setup-macs3-remote-tool
Clone the repo
git clone --depth 1 https://github.com/mims-harvard/ToolUniverse

Made for: Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for setup-macs3-remote-tool

README.md
[![agentmods](https://agentmods.dev/badge/skills/mims-harvard/tooluniverse/setup-macs3-remote-tool/github.svg)](https://agentmods.dev/skills/mims-harvard/tooluniverse/setup-macs3-remote-tool)
Your own site
<a href="https://agentmods.dev/skills/mims-harvard/tooluniverse/setup-macs3-remote-tool"><img src="https://agentmods.dev/badge/skills/mims-harvard/tooluniverse/setup-macs3-remote-tool/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for setup-macs3-remote-tool

Your own site · 80×15
<a href="https://agentmods.dev/skills/mims-harvard/tooluniverse/setup-macs3-remote-tool"><img src="https://agentmods.dev/badge/skills/mims-harvard/tooluniverse/setup-macs3-remote-tool.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 42 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,920 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin 77% copy Near-identical to another mod in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00042 $0.01920
Opus 5 $0.00021 $0.00960
Sonnet 5 $0.00008 $0.00384
Haiku 4.5 $0.00004 $0.00192

Measured 7d ago against content hash 1b401257b0fc, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-11, from the pricing page.

Security

Grade A, and why

setup-macs3-remote-tool scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 7d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

Origin

This is a copy

77% identical to setup-liana-remote-tool — 60 lines differ, which has more behind it and is treated as the original. This page carries a canonical link to it rather than competing with it.

skills/setup-macs3-remote-tool/SKILL.md · 174 lines

How it starts

The opening of the file, as written. The whole thing — 174 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Set up MACS3 as a remote tool

Validation status (2026-08-16): compiled MACS3 3.0.4, loopback discovery/call, and provider-root rejection passed; the current documented no-model/fixed-extension synthetic BED call returned three peaks. Public publication, cross-user isolation, representative accuracy, broad concurrency, cancellation, and recovery remain incomplete. Authenticated private Platform import and owner testing passed on 2026-08-16; public publication and independent-caller authorization/isolation remain untested.

Prerequisites

  • Run from the ToolUniverse repository root on Linux with Python 3.12.3.
  • CPU only; allocate temporary disk for alignment files.
  • Keep provider data, weights, caches, and credentials outside Git.
  • Bind to loopback. A non-loopback bind requires TOOLUNIVERSE_API_TOKEN; never put it in arguments or results.

Run the standard-library contract check before downloading large dependencies:

python scripts/remote_validation/setup_skill_preflight.py --implementation macs3

After exporting provider resources, add --check-provider-env. After the server starts, add --live to verify the exact MCP tool set without running the model. Before sharing, add --check-connect-prereqs; this reports only whether a key is set and never prints its value.

Create an isolated environment

python3 -m venv .venvs/macs3
. .venvs/macs3/bin/activate
python -m pip install --upgrade pip
python -m pip install -e .
python -m pip install -r src/tooluniverse/remote/macs3/requirements.txt

The clean install passed with a workspace-local CPython distribution containing development headers. On ARM64 hosts without MACS3 wheels, ensure Python development headers are available before building, and retain the resulting install evidence.

Obtain credentials, data, and model weights

  • Set TOOLUNIVERSE_REMOTE_DATA_ROOT for provider-owned BED/BAM files. Only approved relative treatment/control paths are accepted; verify data rights.

Read the full file on GitHub · 174 lines

Files

What ships with it

1 file beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 7d ago First seen · 174 lines · 42 tokens per session scan A 1b401257b0fc

Subscribe to this mod's changes

setup-macs3-remote-tool is a skill published in the GitHub repository mims-harvard/ToolUniverse (1,680 stars, last pushed yesterday), licensed Apache-2.0. It adds 42 tokens to every session and 1,920 once invoked, about $0.0002 per session on Opus 5. A static security scan graded it A with 0 findings. It is 77% identical to setup-liana-remote-tool, differing in 60 lines, and is treated as a copy.

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