Borrowing it
Nothing to install: this file belongs to monarch-initiative/dismech. Take a copy, put it at the same path in your own repository, and replace the rules that are about this project with yours.
curl -O https://raw.githubusercontent.com/monarch-initiative/dismech/main/.claude/skills/cancer-curator/SKILL.mdgit clone --depth 1 https://github.com/monarch-initiative/dismechWrote this? Show the measurements
A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.
[](https://agentmods.dev/skills/monarch-initiative/dismech/cancer-curator)<a href="https://agentmods.dev/skills/monarch-initiative/dismech/cancer-curator"><img src="https://agentmods.dev/badge/skills/monarch-initiative/dismech/cancer-curator/github.svg" alt="Measured on agentmods" height="20"></a>Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.
<a href="https://agentmods.dev/skills/monarch-initiative/dismech/cancer-curator"><img src="https://agentmods.dev/badge/skills/monarch-initiative/dismech/cancer-curator.svg" alt="Reviewed on agentmods" width="80" height="20"></a>- NVIDIA SkillSpector pass
What it costs to keep this loaded
Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.
| Model | Per session | Once invoked |
|---|---|---|
| Fable 5.1 | $0.00083 | $0.03745 |
| Opus 5 | $0.00042 | $0.01872 |
| Sonnet 5 | $0.00017 | $0.00749 |
| Haiku 4.5 | $0.00008 | $0.00375 |
Grade A, and why
cancer-curator scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 3d ago.
A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.
Nothing flagged
None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.
How it starts
The opening of the file, as written. The whole thing — 422 lines — stays where its author put it; the contents beside it link to each section on GitHub.
Cancer Curation Skill
Overview
Curate cancer and neoplastic disease entries in the dismech knowledge base with a focus on:
- Genetic drivers (oncogenes, tumor suppressors, fusion genes)
- Pathophysiology with causal chains
- Histopathology findings
- Targeted therapies and their molecular targets
- NCIT terms for biomarkers, gene products, and histologic findings
When to Use
- Creating new cancer/neoplasm entries
- Adding genetic driver information (BCR-ABL, KIT, RET, RB1, etc.)
- Structuring pathophysiology as atomic processes with causal links
- Adding histopathology findings (grades, patterns, rosettes)
- Linking treatments to their molecular targets
- Adding CHEBI terms for chemotherapy drugs
- Adding NCIT terms for biomarkers and fusion proteins
When creating a new cancer or neoplasm entry, first run the duplicate preflight
from initiate-new-disorder-creation: check the latest origin/main
knowledgebase, all PRs, and all issues by MONDO ID, preferred label, and major
synonyms. Do not create a separate cancer entry if an existing KB file, PR, or
issue already covers the same disease concept.
Granularity: which level gets its own entry?
Follow the cancer granularity ladder in design decisions §3a
(docs/explanation/design-decisions.md) — it is the ratified policy and
supersedes the older "molecular subtypes as discrete entities" framing in
projects/CANCER.md:
- Default entry level = histologic entity (WHO blue-book / ICD-O level: PDAC, SCLC, DLBCL) or WHO/ICC molecularly defined entity (IDH-wildtype GBM, APL with PML::RARA, NPM1-mutant AML).
- Biomarker/therapy strata (EGFR-mutant NSCLC, MSI-H CRC, TNBC): default
has_subtypes; a separate entry requires ≥2 stratum-specific pathophysiology nodes AND a distinct first-line therapy/diagnostic pathway. When promoted:skos:narrowMatchmondo_mapping if no exact MONDO term exists (file an NTR), record overlap with non-disjoint sibling strata, add the entry to a covering grouping, and leave a pointer subtype in the parent. - Variant tiers stay
has_subtypesinside the stratum entry unless therapy is variant-specific (KRAS G12C). - Stage/metastasis is never an entry — use
stages:+conforms_to: "invasion_and_metastasis#...". Do not createMetastatic_Xfiles. - Pathways/hallmarks are never entries — modules + groupings.
- Germline predisposition syndromes follow the Mendelian rules and stay separate from the somatic cancers they predispose to.
What this file has done since we first saw it
Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.
- 3d ago Changed · +40 lines 29f53231c9d4
- 12d ago First seen · 382 lines · 83 tokens per session scan A 02bb638a4d60
cancer-curator is a skill published in the GitHub repository monarch-initiative/dismech (61 stars, last pushed today), licensed BSD-3-Clause. It adds 83 tokens to every session and 3,745 once invoked, about $0.0004 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.
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