drug-discovery

drug-discovery is a skill for Claude Code, Codex from NousResearch/hermes-agent. It costs 19 tokens per session (2,717 once invoked), scanned A, original, MIT.

A pharmaceutical research helper for searching ChEMBL, a public database of drug compounds and their biological activity, and checking drug-likeness and interactions.

In plain words
What is it for?
Use it to search compounds by target, activity, or molecule name, then review bioactivity, drug-likeness, and interaction information.
Why use it?
It reduces the manual work of finding relevant compounds and comparing their known properties and effects.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one. Also seen: positional $N argument.

Good fit Use it to search compounds by target, activity, or molecule name, then review bioactivity, drug-likeness, and interaction information.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/nousresearch/hermes-agent/drug-discovery
About the project

Hermes Agent is an AI assistant that learns from its use by creating and improving skills, retaining knowledge, searching past conversations, and adapting to its users. It is for people who want to run an agent through a terminal or messaging platforms while connecting it to different AI models and scheduled tasks.

NousResearch/hermes-agent · 244,603 stars · on GitHub · hermes-agent.nousresearch.com

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add NousResearch/hermes-agent --skill drug-discovery
Clone the repo
git clone --depth 1 https://github.com/NousResearch/hermes-agent

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for drug-discovery

README.md
[![agentmods](https://agentmods.dev/badge/skills/nousresearch/hermes-agent/drug-discovery/github.svg)](https://agentmods.dev/skills/nousresearch/hermes-agent/drug-discovery)
Your own site
<a href="https://agentmods.dev/skills/nousresearch/hermes-agent/drug-discovery"><img src="https://agentmods.dev/badge/skills/nousresearch/hermes-agent/drug-discovery/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for drug-discovery

Your own site · 80×15
<a href="https://agentmods.dev/skills/nousresearch/hermes-agent/drug-discovery"><img src="https://agentmods.dev/badge/skills/nousresearch/hermes-agent/drug-discovery.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 19 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 2,717 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 1 finding. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • Snyk pass 7 Sept 2026
  • NVIDIA SkillSpector warn 7 Sept 2026
SkillSpector: 12 findings, up to high

These are SkillSpector’s own severities. On a checked sample its high-severity flags on skills were ~96% false positives — a documented command, a public API, a “never do X” rule — so we show them as a caution to read, not a verdict. Why →

  • high Supply Chain · line 32
    Remote code is downloaded and executed. This bypasses code review and could introduce malicious code.
    Fix: Avoid downloading and executing remote scripts. Use trusted packages from PyPI/npm. If remote fetch is required, verify checksums and use HTTPS.
  • high Supply Chain · line 48
    Remote code is downloaded and executed. This bypasses code review and could introduce malicious code.
    Fix: Avoid downloading and executing remote scripts. Use trusted packages from PyPI/npm. If remote fetch is required, verify checksums and use HTTPS.
  • high Supply Chain · line 62
    Remote code is downloaded and executed. This bypasses code review and could introduce malicious code.
    Fix: Avoid downloading and executing remote scripts. Use trusted packages from PyPI/npm. If remote fetch is required, verify checksums and use HTTPS.
  • high Supply Chain · line 87
    Remote code is downloaded and executed. This bypasses code review and could introduce malicious code.
    Fix: Avoid downloading and executing remote scripts. Use trusted packages from PyPI/npm. If remote fetch is required, verify checksums and use HTTPS.
  • high Supply Chain · line 118
    Remote code is downloaded and executed. This bypasses code review and could introduce malicious code.
    Fix: Avoid downloading and executing remote scripts. Use trusted packages from PyPI/npm. If remote fetch is required, verify checksums and use HTTPS.
  • high Supply Chain · line 139
    Remote code is downloaded and executed. This bypasses code review and could introduce malicious code.
    Fix: Avoid downloading and executing remote scripts. Use trusted packages from PyPI/npm. If remote fetch is required, verify checksums and use HTTPS.
  • high Supply Chain · line 160
    Remote code is downloaded and executed. This bypasses code review and could introduce malicious code.
    Fix: Avoid downloading and executing remote scripts. Use trusted packages from PyPI/npm. If remote fetch is required, verify checksums and use HTTPS.
  • high Supply Chain · line 174
    Remote code is downloaded and executed. This bypasses code review and could introduce malicious code.
    Fix: Avoid downloading and executing remote scripts. Use trusted packages from PyPI/npm. If remote fetch is required, verify checksums and use HTTPS.
  • medium Data Exfiltration · line 118
    Data is being sent to an external URL. This could be legitimate telemetry or data exfiltration. Manual review is recommended.
    Fix: Verify the destination URL is trusted and necessary. Remove or replace with documented APIs. Ensure no secrets, tokens, or PII are transmitted.
  • medium Data Exfiltration · line 139
    Data is being sent to an external URL. This could be legitimate telemetry or data exfiltration. Manual review is recommended.
    Fix: Verify the destination URL is trusted and necessary. Remove or replace with documented APIs. Ensure no secrets, tokens, or PII are transmitted.
  • medium Data Exfiltration · line 174
    Data is being sent to an external URL. This could be legitimate telemetry or data exfiltration. Manual review is recommended.
    Fix: Verify the destination URL is trusted and necessary. Remove or replace with documented APIs. Ensure no secrets, tokens, or PII are transmitted.
  • medium Data Exfiltration · line 174
    Data is being sent to an external URL. This could be legitimate telemetry or data exfiltration. Manual review is recommended.
    Fix: Verify the destination URL is trusted and necessary. Remove or replace with documented APIs. Ensure no secrets, tokens, or PII are transmitted.
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00019 $0.02717
Opus 5 $0.00010 $0.01358
Sonnet 5 $0.00004 $0.00543
Haiku 4.5 $0.00002 $0.00272

Measured 8d ago against content hash 83ce85111e3a, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-11, from the pricing page.

Security

Grade A, and why

drug-discovery scanned grade A with 1 finding against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 8d ago.

The scan reads SKILL.md. This mod also ships 2 executable files (scripts/chembl_target.py, scripts/ro5_screen.py), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Makes network callslowCapability

Not a fault in itself. Listed so you know the mod talks to something, and to what.

commands: [curl, python]
Origin

Copies of this mod

8 near-identical copies found in the catalogue:

optional-skills/research/drug-discovery/SKILL.md · 222 lines

How it starts

The opening of the file, as written. The whole thing — 222 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Drug Discovery & Pharmaceutical Research

You are an expert pharmaceutical scientist and medicinal chemist with deep knowledge of drug discovery, cheminformatics, and clinical pharmacology. Use this skill for all pharma/chemistry research tasks.

Core Workflows

1 — Bioactive Compound Search (ChEMBL)

Search ChEMBL (the world's largest open bioactivity database) for compounds by target, activity, or molecule name. No API key required.

# Search compounds by target name (e.g. "EGFR", "COX-2", "ACE")
TARGET="$1"
ENCODED=$(python -c "import urllib.parse,sys; print(urllib.parse.quote(sys.argv[1]))" "$TARGET")
curl -s "https://www.ebi.ac.uk/chembl/api/data/target/search?q=${ENCODED}&format=json" \
  | python -c "
import json,sys
data=json.load(sys.stdin)
targets=data.get('targets',[])[:5]
for t in targets:
    print(f\"ChEMBL ID : {t.get('target_chembl_id')}\")
    print(f\"Name      : {t.get('pref_name')}\")
    print(f\"Type      : {t.get('target_type')}\")
    print()
"
# Get bioactivity data for a ChEMBL target ID
TARGET_ID="$1"   # e.g. CHEMBL203
curl -s "https://www.ebi.ac.uk/chembl/api/data/activity?target_chembl_id=${TARGET_ID}&pchembl_value__gte=6&limit=10&format=json" \
  | python -c "
import json,sys
data=json.load(sys.stdin)
acts=data.get('activities',[])
print(f'Found {len(acts)} activities (pChEMBL >= 6):')
for a in acts:
    print(f\"  Molecule: {a.get('molecule_chembl_id')}  |  {a.get('standard_type')}: {a.get('standard_value')} {a.get('standard_units')}  |  pChEMBL: {a.get('pchembl_value')}\")
"
# Look up a specific molecule by ChEMBL ID
MOL_ID="$1"   # e.g. CHEMBL25 (aspirin)
curl -s "https://www.ebi.ac.uk/chembl/api/data/molecule/${MOL_ID}?format=json" \
  | python -c "
import json,sys
m=json.load(sys.stdin)
props=m.get('molecule_properties',{}) or {}
print(f\"Name       : {m.get('pref_name','N/A')}\")
print(f\"SMILES     : {m.get('molecule_structures',{}).get('canonical_smiles','N/A') if m.get('molecule_structures') else 'N/A'}\")
print(f\"MW         : {props.get('full_mwt','N/A')} Da\")
print(f\"LogP       : {props.get('alogp','N/A')}\")
print(f\"HBD        : {props.get('hbd','N/A')}\")
print(f\"HBA        : {props.get('hba','N/A')}\")
print(f\"TPSA       : {props.get('psa','N/A')} Ų\")
print(f\"Ro5 violations: {props.get('num_ro5_violations','N/A')}\")
print(f\"QED        : {props.get('qed_weighted','N/A')}\")
"

Read the full file on GitHub · 222 lines

Files

What ships with it

3 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 8d ago First seen · 222 lines · 19 tokens per session scan A 83ce85111e3a

Subscribe to this mod's changes

drug-discovery is a skill published in the GitHub repository NousResearch/hermes-agent (244,603 stars, last pushed today), licensed MIT. It adds 19 tokens to every session and 2,717 once invoked, about $0.0001 per session on Opus 5. A static security scan graded it A with 1 finding (makes network calls). No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.

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