bio-transcription-translation

bio-transcription-translation is a skill for Claude Code, Codex from thesecondfox/skill. It costs 43 tokens per session (1,866 once invoked), scanned A, original, MIT.

A Biopython toolkit for converting DNA to RNA and translating sequence information into protein. Translation reads codons using a chosen genetic code.

In plain words
What is it for?
Use it to transcribe DNA, convert RNA back to DNA, translate sequences, find open reading frames, and use alternative codon tables.
Why use it?
It avoids manually replacing bases and decoding codons, including when checking alternative reading frames.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to transcribe DNA, convert RNA back to DNA, translate sequences, find open reading frames, and use alternative codon tables.

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Install with agentmods
npx agentmods add skills/thesecondfox/skill/bio-sequence-manipulation-transcription-translation
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add thesecondfox/skill --skill bio-sequence-manipulation-transcription-translation
Clone the repo
git clone --depth 1 https://github.com/thesecondfox/skill

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for bio-transcription-translation

README.md
[![agentmods](https://agentmods.dev/badge/skills/thesecondfox/skill/bio-sequence-manipulation-transcription-translation/github.svg)](https://agentmods.dev/skills/thesecondfox/skill/bio-sequence-manipulation-transcription-translation)
Your own site
<a href="https://agentmods.dev/skills/thesecondfox/skill/bio-sequence-manipulation-transcription-translation"><img src="https://agentmods.dev/badge/skills/thesecondfox/skill/bio-sequence-manipulation-transcription-translation/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for bio-transcription-translation

Your own site · 80×15
<a href="https://agentmods.dev/skills/thesecondfox/skill/bio-sequence-manipulation-transcription-translation"><img src="https://agentmods.dev/badge/skills/thesecondfox/skill/bio-sequence-manipulation-transcription-translation.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 43 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,866 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00043 $0.01866
Opus 5 $0.00022 $0.00933
Sonnet 5 $0.00009 $0.00373
Haiku 4.5 $0.00004 $0.00187

Measured 8d ago against content hash ddf6f060bc0d, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-12, from the pricing page.

Security

Grade A, and why

bio-transcription-translation scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 8d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

Common_Skills/bio-sequence-manipulation-transcription-translation/SKILL.md · 241 lines

How it starts

The opening of the file, as written. The whole thing — 241 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Version Compatibility

Reference examples tested with: BioPython 1.83+

Before using code patterns, verify installed versions match. If versions differ:

  • Python: pip show <package> then help(module.function) to check signatures

If code throws ImportError, AttributeError, or TypeError, introspect the installed package and adapt the example to match the actual API rather than retrying.

Transcription and Translation

"Translate my DNA sequence to protein" → Transcribe DNA to RNA and translate to protein, handling alternative codon tables and six-frame translation.

  • Python: Seq.translate(), Seq.transcribe() (BioPython)

Convert between DNA, RNA, and protein sequences using Biopython.

Required Import

from Bio.Seq import Seq

Core Methods

Transcription (DNA to RNA)

dna = Seq('ATGCGATCGATCG')
rna = dna.transcribe()  # Returns Seq('AUGCGAUCGAUCG')

Transcription replaces T with U. Works on coding strand (5' to 3').

Back Transcription (RNA to DNA)

rna = Seq('AUGCGAUCGAUCG')
dna = rna.back_transcribe()  # Returns Seq('ATGCGATCGATCG')

Translation (RNA/DNA to Protein)

# From coding DNA (includes ATG start)
coding_dna = Seq('ATGTTTGGT')
protein = coding_dna.translate()  # Returns Seq('MFG')

# From RNA
rna = Seq('AUGUUUGGU')
protein = rna.translate()  # Returns Seq('MFG')

Translation Options

Stop at First Stop Codon

seq = Seq('ATGTTTGGTTAAGGG')
protein = seq.translate(to_stop=True)  # Stops at TAA, excludes stop

Include Stop Codon Symbol

seq = Seq('ATGTTTGGTTAA')
protein = seq.translate()  # Returns Seq('MFG*')

Alternative Codon Tables

Biopython supports NCBI codon tables. Common tables:

ID Name Use Case
1 Standard Default, most organisms
2 Vertebrate Mitochondrial Human/vertebrate mitochondria
4 Mold Mitochondrial Fungi, protozoa mitochondria
5 Invertebrate Mitochondrial Insects, worms mitochondria
6 Ciliate Nuclear Tetrahymena, Paramecium
11 Bacterial/Archaeal Prokaryotes, plastids

Read the full file on GitHub · 241 lines

Files

What ships with it

1 file beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 8d ago First seen · 241 lines · 43 tokens per session scan A ddf6f060bc0d

Subscribe to this mod's changes

bio-transcription-translation is a skill published in the GitHub repository thesecondfox/skill (3 stars, last pushed 5mo ago), licensed MIT. It adds 43 tokens to every session and 1,866 once invoked, about $0.0002 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.

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