evo2

evo2 is a skill for Claude Code, Codex from UnicomAI/wanwu. It costs 83 tokens per session (1,482 once invoked), scanned A, a copy of evo2, Apache-2.0.

A skill for using Evo 2, a DNA language model that analyzes and generates DNA sequences.

In plain words
What is it for?
Use it to score variants, embed genomic regions for classification, or generate DNA from a starting sequence when the required Python and GPU setup is available.
Why use it?
It provides a defined way to score sequences, compare their likelihood under the model, create numerical representations, and generate new DNA.

Skill for Claude CodeCodex

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

agentmods
npx agentmods add skills/unicomai/wanwu/evo2
Any agent
npx skills add UnicomAI/wanwu --skill evo2
Clone the repo
git clone --depth 1 https://github.com/UnicomAI/wanwu

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for evo2

README.md
[![agentmods](https://agentmods.dev/badge/skills/unicomai/wanwu/evo2.svg)](https://agentmods.dev/skills/unicomai/wanwu/evo2)
Your own site
<a href="https://agentmods.dev/skills/unicomai/wanwu/evo2"><img src="https://agentmods.dev/badge/skills/unicomai/wanwu/evo2.svg" alt="Measured on agentmods" height="20"></a>
Per session 83 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,482 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. Scan, not verified.
Origin 98% copy Near-identical to another mod in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5 $0.00083 $0.01482
Opus 5 $0.00042 $0.00741
Sonnet 5 $0.00017 $0.00296
Haiku 4.5 $0.00008 $0.00148

Measured 4d ago against content hash fe8268806919, method: parsed. Prices are Anthropic first-party input rates as of 2026-08-30, from the pricing page.

Security

Grade A, and why

evo2 scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 4d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

Origin

This is a copy

98% identical to evo2 — 54 lines differ, which has more behind it and is treated as the original. This page carries a canonical link to it rather than competing with it.

configs/microservice/bff-service/configs/agent-skills/claude-science/evo2/SKILL.md · 154 lines

How it starts

The opening of the file, as written. The whole thing — 154 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Evo 2 — DNA Language Model

Prerequisites

Requirement Minimum Recommended
Python 3.11 3.12 (<3.13)
CUDA 12.1+ 12.4+
GPU VRAM 24 GB (7B bf16) 80 GB (40B)
RAM 32 GB 128 GB

How to run

Installation

pip install evo2
# Weights pulled from Hugging Face on first model load.

Loading and scoring

from evo2 import Evo2

model = Evo2("evo2_7b")        # or "evo2_40b" — see model table
seqs = ["ATCG" * 50, "GGGCTTAA" * 25]
ll = model.score_sequences(seqs)   # → list[float], mean per-token log-likelihood
print(ll)

Generation

out = model.generate(
    prompt_seqs=["ATGAAAGCT"],
    n_tokens=256,
    temperature=0.7,
)
print(out.sequences[0])

Models

Name Params Context VRAM (bf16) Notes
evo2_7b 7 B 1 M nt ~22 GB Default; fits on a single 24 GB+ GPU
evo2_40b 40 B 1 M nt ~78 GB H100 80 GB or multi-GPU
evo2_1b_base 1 B 8 K nt ~6 GB FP8 path requires sm_89+ (H100)

Output format

score_sequences returns a list[float] (or np.ndarray) of mean log-likelihoods, one per input sequence. More negative ⇒ less likely under the model. For variant effect, compute Δll = ll_alt - ll_ref over a fixed window.

generate returns a GenerationOutput with .sequences (list[str]), .logits (list[Tensor]), and .logprobs_mean (list[float]) — always populated, no flag required.

Decision tree

Need a DNA model?
│
├─ Per-base/per-sequence likelihood, generation → Evo 2 ✓
├─ Predict experimental tracks (expression, accessibility) → borzoi
└─ Protein, not DNA → fair-esm2 / esmfold2

Remote compute

7B/40B inference is GPU-bound (≥24 GB / 80 GB VRAM). Read compute_details({provider, mode:'read'}) for an environment with evo2 + flash-attn and a pre-cached HF weight mount, then submit:

Read the full file on GitHub · 154 lines

Files

What ships with it

1 file beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 4d ago First seen · 154 lines · 83 tokens per session scan A fe8268806919

Subscribe to this mod's changes

evo2 is a skill published in the GitHub repository UnicomAI/wanwu (2,455 stars, last pushed 1mo ago), licensed Apache-2.0. It adds 83 tokens to every session and 1,482 once invoked, about $0.0004 per session on Opus 5. A static security scan graded it A with 0 findings. It is 98% identical to evo2, differing in 54 lines, and is treated as a copy.

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