FridrichMethod

FridrichMethod/awesome-skills

Skill Claude CodeCodex

An AI-based health analysis system that combines health data from multiple sources to find unusual patterns, assess health risks, answer questions, and create health reports.

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Use after generating code, after accepting AI suggestions, or when reviewing AI-written modules. Also use when code works but feels brittle, when error handling seems thin, when orphaned resources or missing cleanup are suspected, or when the agent claims done but hidden debt may exist. Catches the specific failure…

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Engineering operating model for teams where AI agents generate a large share of implementation output.

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Regression testing strategies for AI-assisted development. Sandbox-mode API testing without database dependencies, automated bug-check workflows, and patterns to catch AI blind spots where the same model writes and reviews code.

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Eliminates AI-generated writing patterns that erode reader trust. Use when writing or editing articles, docs, or press releases.

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Build production Apache Airflow DAGs with best practices for operators, sensors, testing, and deployment. Use when creating data pipelines, orchestrating workflows, or scheduling batch jobs.

FridrichMethod/awesome-skills

Skill Claude CodeCodex

AiZynthFinder retrosynthetic route planning (CASP) from AstraZeneca Molecular AI. Monte Carlo tree search guided by a template-based neural expansion policy recursively disconnects a target SMILES until precursors are found in a purchasable stock. Covers config.yml (v4 format), aizynthcli batch screening, the…

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Creating algorithmic art using p5.js with seeded randomness and interactive parameter exploration. Use this when users request creating art using code, generative art, algorithmic art, flow fields, or particle systems. Create original algorithmic art rather than copying existing artists' work to avoid copyright…

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Trim PCR primers from aligned reads in amplicon-panel BAMs using samtools ampliconclip. Use when processing SARS-CoV-2 ARTIC, hereditary cancer panels, ctDNA hot-spot panels, or any amplicon assay where primer-derived bases would falsely confirm reference at primer footprints.

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Filter alignments by flags, mapping quality, and regions using samtools view and pysam. Use when extracting specific reads, removing low-quality alignments, or subsetting to target regions.

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Quantify transcript expression from FASTQ with Salmon (selective alignment) or kallisto (pseudoalignment), bypassing genome mapping. Use when quantifying RNA-seq without alignment, deciding whether a decoy-aware index is required, detecting and verifying library strandedness, enabling GC and sequence bias correction…

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Create and use BAI/CSI indices for BAM/CRAM files using samtools and pysam. Use when enabling random access to alignment files or fetching specific genomic regions.