comorbidity-common-immune-biomarker-research-planner

comorbidity-common-immune-biomarker-research-planner is a skill for Claude Code, Codex from aipoch/medical-research-skills. It costs 156 tokens per session (3,614 once invoked), scanned A, original, MIT.

A research-planning guide for finding biological signals shared by two related diseases, especially signals involving the immune system. It combines gene-expression comparisons with network analysis, feature selection, diagnostic checks, and public-data validation.

In plain words
What is it for?
Use it to plan shared-biomarker studies involving differential expression, pathway analysis, protein networks, machine-learning feature selection, diagnostic validation, immune analysis, and gene-regulation networks.
Why use it?
It gives comorbidity studies a structured path from two disease datasets to cautiously tested shared biomarkers. This helps keep statistical patterns separate from claims about how the diseases cause each other.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to plan shared-biomarker studies involving differential expression, pathway analysis, protein networks, machine-learning feature selection, diagnostic validation, immune analysis, and gene-regulation networks.

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Install with agentmods
npx agentmods add skills/aipoch/medical-research-skills/comorbidity-common-immune-biomarker-research-planner
About the project

Medical Research Agent Skills is a library of agent instructions for medical and biomedical research, covering evidence analysis, study protocol design, data analysis, and academic writing. Researchers use it to guide compatible coding agents through common scientific workflows. The catalogue contains many of the library's skills and commands.

aipoch/medical-research-skills · 1,860 stars · on GitHub · aipoch.com

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add aipoch/medical-research-skills --skill comorbidity-common-immune-biomarker-research-planner
Clone the repo
git clone --depth 1 https://github.com/aipoch/medical-research-skills

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for comorbidity-common-immune-biomarker-research-planner

README.md
[![agentmods](https://agentmods.dev/badge/skills/aipoch/medical-research-skills/comorbidity-common-immune-biomarker-research-planner/github.svg)](https://agentmods.dev/skills/aipoch/medical-research-skills/comorbidity-common-immune-biomarker-research-planner)
Your own site
<a href="https://agentmods.dev/skills/aipoch/medical-research-skills/comorbidity-common-immune-biomarker-research-planner"><img src="https://agentmods.dev/badge/skills/aipoch/medical-research-skills/comorbidity-common-immune-biomarker-research-planner/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for comorbidity-common-immune-biomarker-research-planner

Your own site · 80×15
<a href="https://agentmods.dev/skills/aipoch/medical-research-skills/comorbidity-common-immune-biomarker-research-planner"><img src="https://agentmods.dev/badge/skills/aipoch/medical-research-skills/comorbidity-common-immune-biomarker-research-planner.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 156 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 3,614 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00156 $0.03614
Opus 5 $0.00078 $0.01807
Sonnet 5 $0.00031 $0.00723
Haiku 4.5 $0.00016 $0.00361

Measured 9d ago against content hash 9151fc521745, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-12, from the pricing page.

Security

Grade A, and why

comorbidity-common-immune-biomarker-research-planner scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 9d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

awesome-med-research-skills/Protocol Design/comorbidity-common-immune-biomarker-research-planner/SKILL.md · 247 lines

How it starts

The opening of the file, as written. The whole thing — 247 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Source: https://github.com/aipoch/medical-research-skills

Comorbidity Common-Immune Biomarker Research Planner

You are an expert comorbidity-oriented comparative bioinformatics and translational biomarker research planner.

Task: Generate a complete, structured research design — not a literature summary, not a tool list. A real, executable study plan with four workload options and a recommended primary path.

This skill is designed for article patterns like: disease A dataset selection + disease B dataset selection → per-disease DEG analysis → shared DEG intersection → GO / KEGG enrichment → PPI network and hub-gene prioritization → machine-learning feature selection → external diagnostic validation → gene-gene / TF-gene interaction analysis → immune infiltration analysis → cautious mechanistic interpretation. Do not mechanically copy any anchor paper; generalize the pattern into a reusable comorbidity shared-biomarker study-design framework.


Input Validation

Valid input: [disease A] + [disease B] + [shared biomarker / immune / validation direction] Optional additions: public-data-only, immune angle, machine-learning angle, regulatory-network interest, external validation scope, preferred config level.

Examples:

  • "Atrial fibrillation and chronic kidney disease. Need shared biomarker and immune-related study."
  • "Cardiovascular disease plus metabolic comorbidity with shared DEGs, hub genes, and immune infiltration."
  • "Two related chronic diseases with GEO discovery and external validation."
  • "Need common genes, machine-learning biomarker selection, TF network, and immune-cell analysis."

Out-of-scope — respond with the redirect below and stop:

  • Clinical treatment recommendations, patient-specific diagnosis, prescribing
  • Pure single-disease prognostic-model studies with no disease-pair comparison
  • Pure wet-lab mechanistic studies with no bioinformatics backbone
  • Pure omics studies with no shared-DEG / hub-gene / biomarker logic
  • Non-biomedical / off-topic requests

Read the full file on GitHub · 247 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 9d ago First seen · 247 lines · 156 tokens per session scan A 9151fc521745

Subscribe to this mod's changes

comorbidity-common-immune-biomarker-research-planner is a skill published in the GitHub repository aipoch/medical-research-skills (1,860 stars, last pushed 1mo ago), licensed MIT. It adds 156 tokens to every session and 3,614 once invoked, about $0.0008 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.