cross-disease-shared-biomarker-network-research-planner

cross-disease-shared-biomarker-network-research-planner is a skill for Claude Code, Codex from aipoch/medical-research-skills. It costs 184 tokens per session (3,686 once invoked), scanned A, original, MIT.

A research-planning guide for comparing two diseases through shared gene-expression patterns and biological networks. It helps identify genes that change in both diseases and investigate their pathways, interactions, regulation, and possible treatment relevance.

In plain words
What is it for?
Use it to plan studies covering differential gene expression, shared-gene analysis, pathway enrichment, protein-interaction networks, immune context, regulatory networks, drug-candidate screening, and optional laboratory validation.
Why use it?
It organises a complex multi-dataset comparison into a connected study design. This reduces the risk of treating a shared gene list as a meaningful mechanism without further validation.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to plan studies covering differential gene expression, shared-gene analysis, pathway enrichment, protein-interaction networks, immune context, regulatory networks, drug-candidate screening, and optional laboratory validation.

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Install with agentmods
npx agentmods add skills/aipoch/medical-research-skills/cross-disease-shared-biomarker-network-research-planner
About the project

Medical Research Agent Skills is a library of agent instructions for medical and biomedical research, covering evidence analysis, study protocol design, data analysis, and academic writing. Researchers use it to guide compatible coding agents through common scientific workflows. The catalogue contains many of the library's skills and commands.

aipoch/medical-research-skills · 1,860 stars · on GitHub · aipoch.com

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add aipoch/medical-research-skills --skill cross-disease-shared-biomarker-network-research-planner
Clone the repo
git clone --depth 1 https://github.com/aipoch/medical-research-skills

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for cross-disease-shared-biomarker-network-research-planner

README.md
[![agentmods](https://agentmods.dev/badge/skills/aipoch/medical-research-skills/cross-disease-shared-biomarker-network-research-planner/github.svg)](https://agentmods.dev/skills/aipoch/medical-research-skills/cross-disease-shared-biomarker-network-research-planner)
Your own site
<a href="https://agentmods.dev/skills/aipoch/medical-research-skills/cross-disease-shared-biomarker-network-research-planner"><img src="https://agentmods.dev/badge/skills/aipoch/medical-research-skills/cross-disease-shared-biomarker-network-research-planner/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for cross-disease-shared-biomarker-network-research-planner

Your own site · 80×15
<a href="https://agentmods.dev/skills/aipoch/medical-research-skills/cross-disease-shared-biomarker-network-research-planner"><img src="https://agentmods.dev/badge/skills/aipoch/medical-research-skills/cross-disease-shared-biomarker-network-research-planner.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 184 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 3,686 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00184 $0.03686
Opus 5 $0.00092 $0.01843
Sonnet 5 $0.00037 $0.00737
Haiku 4.5 $0.00018 $0.00369

Measured 9d ago against content hash 2dbeb4253fd3, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-12, from the pricing page.

Security

Grade A, and why

cross-disease-shared-biomarker-network-research-planner scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 9d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

awesome-med-research-skills/Protocol Design/cross-disease-shared-biomarker-network-research-planner/SKILL.md · 248 lines

How it starts

The opening of the file, as written. The whole thing — 248 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Source: https://github.com/aipoch/medical-research-skills

Cross-Disease Shared-Biomarker Network Research Planner

You are an expert cross-disease comparative bioinformatics and translational validation research planner.

Task: Generate a complete, structured research design — not a literature summary, not a tool list. A real, executable study plan with four workload options and a recommended primary path.

This skill is designed for article patterns like: multi-dataset disease A selection + disease B selection → DEG analysis in each disease → overlap / shared-DEG extraction → GO / KEGG enrichment → PPI network and hub-gene prioritization → TCGA/HPA/GEPIA-like public validation → TF-gene and TF-miRNA co-regulatory analysis → immune infiltration analysis → DGIdb-like candidate-drug screening → optional qRT-PCR / cell validation. Do not mechanically copy any anchor paper; generalize the pattern into a reusable cross-disease biomarker study-design framework.


Input Validation

Valid input: [disease A] + [disease B] + [shared-biomarker OR mechanism OR validation direction] Optional additions: public-data-only, immune angle, drug-target angle, TF/miRNA network interest, experimental validation scope, preferred config level.

Examples:

  • "Endometriosis and endometrial cancer. Need shared biomarker and hub-gene study."
  • "Chronic inflammatory disease plus related cancer. Shared DEG + immune infiltration + drug target screening."
  • "Two related gynecologic diseases with GEO + TCGA + qRT-PCR validation."
  • "Need common molecular mechanism and candidate therapeutic targets across two diseases."

Out-of-scope — respond with the redirect below and stop:

  • Clinical treatment recommendations, patient-specific diagnosis, prescribing
  • Pure single-disease prognostic model studies with no cross-disease comparison
  • Pure ceRNA-only studies with no shared-DEG / hub-gene backbone
  • Wet-lab-only mechanistic studies with no bioinformatics integration
  • Non-biomedical / off-topic requests

Read the full file on GitHub · 248 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 9d ago First seen · 248 lines · 184 tokens per session scan A 2dbeb4253fd3

Subscribe to this mod's changes

cross-disease-shared-biomarker-network-research-planner is a skill published in the GitHub repository aipoch/medical-research-skills (1,860 stars, last pushed 1mo ago), licensed MIT. It adds 184 tokens to every session and 3,686 once invoked, about $0.0009 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.