drug-repurposing-study-planner

drug-repurposing-study-planner is a skill for Claude Code, Codex from aipoch/medical-research-skills. It costs 47 tokens per session (2,785 once invoked), scanned A, original, MIT.

A study-design guide for investigating whether an existing medicine could be useful for a different disease or biological problem. It links disease mechanisms, drug targets, gene-expression reversal, real-world evidence, and later experimental or clinical checks.

In plain words
What is it for?
Use it to plan repurposing studies that connect disease biology with drug mechanisms, compare gene-expression signatures, examine clinical evidence, and define laboratory or translational validation steps.
Why use it?
It creates an evidence chain from an initial computational idea to validation without treating a prediction as proof that a drug works. This helps researchers plan credible follow-up work.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to plan repurposing studies that connect disease biology with drug mechanisms, compare gene-expression signatures, examine clinical evidence, and define laboratory or translational validation steps.

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Install with agentmods
npx agentmods add skills/aipoch/medical-research-skills/drug-repurposing-study-planner
About the project

Medical Research Agent Skills is a library of agent instructions for medical and biomedical research, covering evidence analysis, study protocol design, data analysis, and academic writing. Researchers use it to guide compatible coding agents through common scientific workflows. The catalogue contains many of the library's skills and commands.

aipoch/medical-research-skills · 1,860 stars · on GitHub · aipoch.com

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add aipoch/medical-research-skills --skill drug-repurposing-study-planner
Clone the repo
git clone --depth 1 https://github.com/aipoch/medical-research-skills

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for drug-repurposing-study-planner

README.md
[![agentmods](https://agentmods.dev/badge/skills/aipoch/medical-research-skills/drug-repurposing-study-planner/github.svg)](https://agentmods.dev/skills/aipoch/medical-research-skills/drug-repurposing-study-planner)
Your own site
<a href="https://agentmods.dev/skills/aipoch/medical-research-skills/drug-repurposing-study-planner"><img src="https://agentmods.dev/badge/skills/aipoch/medical-research-skills/drug-repurposing-study-planner/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for drug-repurposing-study-planner

Your own site · 80×15
<a href="https://agentmods.dev/skills/aipoch/medical-research-skills/drug-repurposing-study-planner"><img src="https://agentmods.dev/badge/skills/aipoch/medical-research-skills/drug-repurposing-study-planner.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 47 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 2,785 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00047 $0.02785
Opus 5 $0.00023 $0.01392
Sonnet 5 $0.00009 $0.00557
Haiku 4.5 $0.00005 $0.00279

Measured 9d ago against content hash e007e5bf07dd, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-12, from the pricing page.

Security

Grade A, and why

drug-repurposing-study-planner scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 9d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

awesome-med-research-skills/Protocol Design/drug-repurposing-study-planner/SKILL.md · 324 lines

How it starts

The opening of the file, as written. The whole thing — 324 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Source: https://github.com/aipoch/medical-research-skills

Drug Repurposing Study Planner

You are a biomedical research planning specialist for drug repurposing study design.

Your job is to design a study-type-level repurposing blueprint, not to act as a full protocol writer, not to fabricate drug claims, and not to jump from computational signal to therapeutic recommendation.

You help the user convert a disease or biological problem into a closed-loop repurposing research route that links:

  • disease mechanism framing,
  • drug-target or mechanism relevance,
  • expression reversal or signature-based evidence when appropriate,
  • real-world or clinical support when appropriate,
  • and validation logic from in silico prioritization to experimental and translational follow-up.

Your output must remain at the level of research design framing and evidence-chain architecture. Do not present any candidate drug as clinically effective unless explicitly supported and verified by the user-provided context.

Task

Given a disease area, phenotype, biological mechanism, target class, omics finding, or translational question, design a drug repurposing study plan that:

  1. identifies the most appropriate repurposing route family,
  2. defines the minimum evidence chain needed for that route,
  3. specifies the main discovery modules,
  4. clarifies the validation ladder,
  5. identifies key assumptions and failure points,
  6. and outputs a coherent study blueprint rather than a list of disconnected analyses.

Important Distinctions

This skill is for drug repurposing study design. It is not interchangeable with:

  • target identification only,
  • disease mechanism mapping only,
  • expression signature comparison only,
  • real-world evidence study design only,
  • or full protocol drafting.

You must explicitly distinguish:

  • target relevance vs druggability vs repurposing readiness,
  • expression reversal evidence vs mechanistic compatibility,
  • computational prioritization vs experimental support,
  • observational support vs causal therapeutic effect,
  • candidate nomination vs clinical recommendation.

Read the full file on GitHub · 324 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 9d ago First seen · 324 lines · 47 tokens per session scan A e007e5bf07dd

Subscribe to this mod's changes

drug-repurposing-study-planner is a skill published in the GitHub repository aipoch/medical-research-skills (1,860 stars, last pushed 1mo ago), licensed MIT. It adds 47 tokens to every session and 2,785 once invoked, about $0.0002 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.