alterlab-alphafold-db

alterlab-alphafold-db is a skill for Claude Code from AlterLab-IEU/AlterLab-Academic-Skills. It costs 144 tokens per session (2,492 once invoked), scanned A, original, MIT.

A lookup tool for AlphaFold DB, a public collection of AI-predicted three-dimensional protein structures. It finds models by UniProt ID, provides structure files, and shows confidence measures such as pLDDT and PAE.

In plain words
What is it for?
Use it to retrieve and download protein models, check prediction reliability, compare predictions with experimental structures, and support drug discovery or protein engineering.
Why use it?
It helps when a protein has no experimentally measured structure, so you can start structural analysis without waiting for laboratory data.

Skill for Claude Code

Written for Claude Code: allowed-tools in frontmatter.

Part of the alterlab-databases plugin — 39 skills shipped together

Good fit Use it to retrieve and download protein models, check prediction reliability, compare predictions with experimental structures, and support drug discovery or protein engineering.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/alterlab-ieu/alterlab-academic-skills/alterlab-alphafold-db
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add AlterLab-IEU/AlterLab-Academic-Skills --skill alterlab-alphafold-db
Clone the repo
git clone --depth 1 https://github.com/AlterLab-IEU/AlterLab-Academic-Skills

Made for: Claude Code.

Or install alterlab-databases, the plugin that ships this one along with the rest of its 39 skills.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for alterlab-alphafold-db

README.md
[![agentmods](https://agentmods.dev/badge/skills/alterlab-ieu/alterlab-academic-skills/alterlab-alphafold-db/github.svg)](https://agentmods.dev/skills/alterlab-ieu/alterlab-academic-skills/alterlab-alphafold-db)
Your own site
<a href="https://agentmods.dev/skills/alterlab-ieu/alterlab-academic-skills/alterlab-alphafold-db"><img src="https://agentmods.dev/badge/skills/alterlab-ieu/alterlab-academic-skills/alterlab-alphafold-db/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for alterlab-alphafold-db

Your own site · 80×15
<a href="https://agentmods.dev/skills/alterlab-ieu/alterlab-academic-skills/alterlab-alphafold-db"><img src="https://agentmods.dev/badge/skills/alterlab-ieu/alterlab-academic-skills/alterlab-alphafold-db.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 144 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 2,492 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 2 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00144 $0.02492
Opus 5 $0.00072 $0.01246
Sonnet 5 $0.00029 $0.00498
Haiku 4.5 $0.00014 $0.00249

Measured 9d ago against content hash 504dcc424b23, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-12, from the pricing page.

Security

Grade A, and why

alterlab-alphafold-db scanned grade A with 2 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 9d ago.

The scan reads SKILL.md. This mod also ships 1 executable file (scripts/query_alphafold.py), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Makes network callslowCapability

Not a fault in itself. Listed so you know the mod talks to something, and to what.

allowed-tools: Read WebFetch Bash(curl:*) Bash(python:*)

Runs shell commandslowCapability

Expected in a hook, worth knowing in a rule or an instructions file.

ID and uses list-form `subprocess.run` (never `shell=True`). See
skills/databases/alterlab-alphafold-db/SKILL.md · 234 lines

How it starts

The opening of the file, as written. The whole thing — 234 lines — stays where its author put it; the contents beside it link to each section on GitHub.

AlphaFold Database

Overview

AlphaFold DB is a public repository of AI-predicted 3D protein structures for over 200 million proteins, maintained by DeepMind and EMBL-EBI. Access structure predictions with confidence metrics, download coordinate files, retrieve bulk datasets, and integrate predictions into computational workflows.

When to Use This Skill

This skill should be used when working with AI-predicted protein structures in scenarios such as:

  • Retrieving protein structure predictions by UniProt ID or protein name
  • Downloading PDB/mmCIF coordinate files for structural analysis
  • Analyzing prediction confidence metrics (pLDDT, PAE) to assess reliability
  • Accessing bulk proteome datasets via Google Cloud Platform
  • Comparing predicted structures with experimental data
  • Performing structure-based drug discovery or protein engineering
  • Building structural models for proteins lacking experimental structures
  • Integrating AlphaFold predictions into computational pipelines

Core Capabilities

Worked, copy-paste Python recipes for every capability below live in references/code_examples.md. Load it when you need runnable code; the summaries here give the routing and the key decisions.

1. Searching and Retrieving Predictions

Three entry points, in order of preference:

  • Biopython (recommended): Bio.PDB.alphafold_db.get_predictions(accession), download_cif_for(...), get_structural_models_for(...) — simplest path.
  • Direct REST: GET https://alphafold.ebi.ac.uk/api/prediction/{uniprot_id}; the AlphaFold ID is response[0]['entryId'].
  • Find accessions first via UniProt when you only have a gene name or PDB ID — use the UniProt ID-mapping job API (get_uniprot_ids helper in code_examples.md §1; valid db names at https://rest.uniprot.org/configure/idmapping/fields).

2. Downloading Structure Files

The /prediction response carries version-stamped file URLs — use those, don't hand-build a _v{N} suffix. The DB version advances (currently v6) and old _v4 file URLs now 404:

Read the full file on GitHub · 234 lines

Files

What ships with it

4 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 9d ago First seen · 234 lines · 144 tokens per session scan A 504dcc424b23

Subscribe to this mod's changes

alterlab-alphafold-db is a skill published in the GitHub repository AlterLab-IEU/AlterLab-Academic-Skills (66 stars, last pushed 8d ago), licensed MIT. It adds 144 tokens to every session and 2,492 once invoked, about $0.0007 per session on Opus 5. A static security scan graded it A with 2 findings (makes network calls, runs shell commands). No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.

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