alterlab-jaspar

alterlab-jaspar is a skill for Claude Code from AlterLab-IEU/AlterLab-Academic-Skills. It costs 82 tokens per session (3,834 once invoked), scanned A, original, MIT.

A DNA motif-analysis tool for JASPAR, an open database of curated profiles showing how transcription factors bind DNA. Transcription factors are proteins that help control gene activity.

In plain words
What is it for?
Use it to search profiles by transcription factor, species, or class; scan DNA sequences for likely binding sites; and compare binding matrices.
Why use it?
It avoids manually gathering binding profiles from different sources and gives sequence analysis a common set of curated profiles.

Skill for Claude Code

Written for Claude Code: allowed-tools in frontmatter.

Part of the alterlab-databases plugin — 39 skills shipped together

Good fit Use it to search profiles by transcription factor, species, or class; scan DNA sequences for likely binding sites; and compare binding matrices.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/alterlab-ieu/alterlab-academic-skills/alterlab-jaspar
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add AlterLab-IEU/AlterLab-Academic-Skills --skill alterlab-jaspar
Clone the repo
git clone --depth 1 https://github.com/AlterLab-IEU/AlterLab-Academic-Skills

Made for: Claude Code.

Or install alterlab-databases, the plugin that ships this one along with the rest of its 39 skills.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for alterlab-jaspar

README.md
[![agentmods](https://agentmods.dev/badge/skills/alterlab-ieu/alterlab-academic-skills/alterlab-jaspar/github.svg)](https://agentmods.dev/skills/alterlab-ieu/alterlab-academic-skills/alterlab-jaspar)
Your own site
<a href="https://agentmods.dev/skills/alterlab-ieu/alterlab-academic-skills/alterlab-jaspar"><img src="https://agentmods.dev/badge/skills/alterlab-ieu/alterlab-academic-skills/alterlab-jaspar/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for alterlab-jaspar

Your own site · 80×15
<a href="https://agentmods.dev/skills/alterlab-ieu/alterlab-academic-skills/alterlab-jaspar"><img src="https://agentmods.dev/badge/skills/alterlab-ieu/alterlab-academic-skills/alterlab-jaspar.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 82 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 3,834 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 1 finding. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00082 $0.03834
Opus 5 $0.00041 $0.01917
Sonnet 5 $0.00016 $0.00767
Haiku 4.5 $0.00008 $0.00383

Measured 7d ago against content hash 5e13fbf641a0, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-12, from the pricing page.

Security

Grade A, and why

alterlab-jaspar scanned grade A with 1 finding against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 7d ago.

The scan reads SKILL.md. This mod also ships 1 executable file (scripts/query_jaspar.py), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Makes network callslowCapability

Not a fault in itself. Listed so you know the mod talks to something, and to what.

allowed-tools: Read WebFetch Bash(curl:*) Bash(python:*)
skills/databases/alterlab-jaspar/SKILL.md · 370 lines

How it starts

The opening of the file, as written. The whole thing — 370 lines — stays where its author put it; the contents beside it link to each section on GitHub.

JASPAR Database

Overview

JASPAR (https://jaspar.elixir.no/) is the gold-standard open-access database of curated, non-redundant transcription factor (TF) binding profiles stored as position frequency matrices (PFMs). The JASPAR 2024 release added 329 new profiles to the CORE collection (~20% growth over the prior release); the live API currently serves ~2,600 latest-version CORE profiles across taxa. Each profile is experimentally derived (ChIP-seq, SELEX, HT-SELEX, protein binding microarray, etc.) and curated.

Key resources:

Scripts

scripts/query_jaspar.py — query the JASPAR REST API (stdlib only, JSON to stdout):

python scripts/query_jaspar.py search --name CTCF --species 9606   # latest-version profiles only
python scripts/query_jaspar.py search --name CTCF --all-versions   # include historical versions
python scripts/query_jaspar.py matrix MA0139.1                     # fetch a matrix (PFM)

search defaults to version=latest (one row per profile); pass --all-versions to see every historical version. --species maps to the API's tax_id param (NCBI taxonomy ID).

When to Use This Skill

Use JASPAR when:

  • TF binding site prediction: Scan a DNA sequence for potential binding sites of a TF
  • Regulatory variant interpretation: Does a GWAS/eQTL variant disrupt a TF binding motif?
  • Promoter/enhancer analysis: What TFs are predicted to bind to a regulatory element?
  • Gene regulatory network construction: Link TFs to their target genes via motif scanning
  • TF family analysis: Compare binding profiles across a TF family (e.g., all homeobox factors)
  • ChIP-seq analysis: Find known TF motifs enriched in ChIP-seq peaks
  • ENCODE/ATAC-seq interpretation: Match open chromatin regions to TF binding profiles

Read the full file on GitHub · 370 lines

Files

What ships with it

3 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 7d ago First seen · 370 lines · 82 tokens per session scan A 5e13fbf641a0

Subscribe to this mod's changes

alterlab-jaspar is a skill published in the GitHub repository AlterLab-IEU/AlterLab-Academic-Skills (66 stars, last pushed 8d ago), licensed MIT. It adds 82 tokens to every session and 3,834 once invoked, about $0.0004 per session on Opus 5. A static security scan graded it A with 1 finding (makes network calls). No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-05.

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