alterlab-scvi-tools

alterlab-scvi-tools is a skill for Claude Code from AlterLab-IEU/AlterLab-Academic-Skills. It costs 102 tokens per session (1,841 once invoked), scanned A, a copy of scvi-tools, MIT.

A Python framework for analyzing single-cell biological data with statistical models that can account for differences between experiments. Single-cell data records measurements from individual cells, while multimodal data combines sources such as gene activity and cell-surface proteins.

In plain words
What is it for?
Use it to integrate single-cell datasets, correct batch effects, compare gene activity, map new cells to a reference, analyze cell types, and work with multimodal or spatial data.
Why use it?
It helps separate real biological differences from technical variation, such as batch effects caused by processing samples at different times or in different laboratories.

Skill for Claude Code

Written for Claude Code: allowed-tools in frontmatter.

Part of the alterlab-bioinformatics plugin — 38 skills shipped together

Good fit Use it to integrate single-cell datasets, correct batch effects, compare gene activity, map new cells to a reference, analyze cell types, and work with multimodal or spatial data.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/alterlab-ieu/alterlab-academic-skills/alterlab-scvi-tools
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add AlterLab-IEU/AlterLab-Academic-Skills --skill alterlab-scvi-tools
Clone the repo
git clone --depth 1 https://github.com/AlterLab-IEU/AlterLab-Academic-Skills

Made for: Claude Code.

Or install alterlab-bioinformatics, the plugin that ships this one along with the rest of its 38 skills.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for alterlab-scvi-tools

README.md
[![agentmods](https://agentmods.dev/badge/skills/alterlab-ieu/alterlab-academic-skills/alterlab-scvi-tools/github.svg)](https://agentmods.dev/skills/alterlab-ieu/alterlab-academic-skills/alterlab-scvi-tools)
Your own site
<a href="https://agentmods.dev/skills/alterlab-ieu/alterlab-academic-skills/alterlab-scvi-tools"><img src="https://agentmods.dev/badge/skills/alterlab-ieu/alterlab-academic-skills/alterlab-scvi-tools/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for alterlab-scvi-tools

Your own site · 80×15
<a href="https://agentmods.dev/skills/alterlab-ieu/alterlab-academic-skills/alterlab-scvi-tools"><img src="https://agentmods.dev/badge/skills/alterlab-ieu/alterlab-academic-skills/alterlab-scvi-tools.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 102 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,841 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin 69% copy Near-identical to another mod in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00102 $0.01841
Opus 5 $0.00051 $0.00920
Sonnet 5 $0.00020 $0.00368
Haiku 4.5 $0.00010 $0.00184

Measured 11d ago against content hash c79d2818b32b, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-11, from the pricing page.

Security

Grade A, and why

alterlab-scvi-tools scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 11d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

Origin

This is a copy

69% identical to scvi-tools — 56 lines differ, which has more behind it and is treated as the original. This page carries a canonical link to it rather than competing with it.

skills/bioinformatics/alterlab-scvi-tools/SKILL.md · 196 lines

How it starts

The opening of the file, as written. The whole thing — 196 lines — stays where its author put it; the contents beside it link to each section on GitHub.

scvi-tools

Overview

scvi-tools is a comprehensive Python framework for probabilistic models in single-cell genomics. Built on PyTorch and PyTorch Lightning, it provides deep generative models using variational inference for analyzing diverse single-cell data modalities.

When to Use This Skill

Use this skill when:

  • Analyzing single-cell RNA-seq data (dimensionality reduction, batch correction, integration)
  • Working with single-cell ATAC-seq or chromatin accessibility data
  • Integrating multimodal data (CITE-seq, multiome, paired/unpaired datasets)
  • Analyzing spatial transcriptomics data (deconvolution, spatial mapping)
  • Performing differential expression analysis on single-cell data
  • Conducting cell type annotation or transfer learning tasks
  • Working with specialized single-cell modalities (methylation, cytometry, RNA velocity)
  • Building custom probabilistic models for single-cell analysis

Core Capabilities

scvi-tools provides models organized by data modality:

1. Single-Cell RNA-seq Analysis

Core models for expression analysis, batch correction, and integration. See references/models-scrna-seq.md for:

  • scVI: Unsupervised dimensionality reduction and batch correction
  • scANVI: Semi-supervised cell type annotation and integration
  • AUTOZI: Zero-inflation detection and modeling
  • VeloVI: RNA velocity analysis
  • contrastiveVI: Perturbation effect isolation

2. Chromatin Accessibility (ATAC-seq)

Models for analyzing single-cell chromatin data. See references/models-atac-seq.md for:

  • PeakVI: Peak-based ATAC-seq analysis and integration
  • PoissonVI: Quantitative fragment count modeling
  • scBasset: Deep learning approach with motif analysis

3. Multimodal & Multi-omics Integration

Joint analysis of multiple data types. See references/models-multimodal.md for:

  • totalVI: CITE-seq protein and RNA joint modeling
  • MultiVI: Paired and unpaired multi-omic integration
  • MrVI: Multi-resolution cross-sample analysis

Read the full file on GitHub · 196 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 11d ago First seen · 196 lines · 102 tokens per session scan A c79d2818b32b

Subscribe to this mod's changes

alterlab-scvi-tools is a skill published in the GitHub repository AlterLab-IEU/AlterLab-Academic-Skills (66 stars, last pushed 6d ago), licensed MIT. It adds 102 tokens to every session and 1,841 once invoked, about $0.0005 per session on Opus 5. A static security scan graded it A with 0 findings. It is 69% identical to scvi-tools, differing in 56 lines, and is treated as a copy.

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