Gene Panel Selection Workflow

Gene Panel Selection Workflow is a skill for Claude Code, Codex from aristoteleo/PantheonOS. It costs 110 tokens per session (6,961 once invoked), scanned A, original, BSD-2-Clause.

A required workflow for choosing gene panels in single-cell RNA sequencing and spatial transcriptomics. A gene panel is a selected set of genes used to identify cell types or biological states.

In plain words
What is it for?
Use it to design and evaluate gene panels with methods such as highly variable genes, differential expression, random forests, scGeneFit, and SpaPROS.
Why use it?
It combines data preparation, algorithmic gene selection, panel-size testing, and biological review in a fixed sequence.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to design and evaluate gene panels with methods such as highly variable genes, differential expression, random forests, scGeneFit, and SpaPROS.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/aristoteleo/pantheonos/gene_panel_selection
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add aristoteleo/PantheonOS --skill gene_panel_selection
Clone the repo
git clone --depth 1 https://github.com/aristoteleo/PantheonOS

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for Gene Panel Selection Workflow

README.md
[![agentmods](https://agentmods.dev/badge/skills/aristoteleo/pantheonos/gene_panel_selection/github.svg)](https://agentmods.dev/skills/aristoteleo/pantheonos/gene_panel_selection)
Your own site
<a href="https://agentmods.dev/skills/aristoteleo/pantheonos/gene_panel_selection"><img src="https://agentmods.dev/badge/skills/aristoteleo/pantheonos/gene_panel_selection/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for Gene Panel Selection Workflow

Your own site · 80×15
<a href="https://agentmods.dev/skills/aristoteleo/pantheonos/gene_panel_selection"><img src="https://agentmods.dev/badge/skills/aristoteleo/pantheonos/gene_panel_selection.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 110 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 6,961 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector warn 7 Sept 2026
SkillSpector: 1 finding, up to high

These are SkillSpector’s own severities. On a checked sample its high-severity flags on skills were ~96% false positives — a documented command, a public API, a “never do X” rule — so we show them as a caution to read, not a verdict. Why →

  • high YARA Match · line 4
    YARA rule matched a hack tool or exploit indicator (offensive tools, reconnaissance, privilege escalation, or exploit frameworks).
    Fix: Remove offensive tool references and exploit code. Legitimate agent skills should not contain penetration testing tools, exploit frameworks, or reconnaissance utilities.
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00110 $0.06961
Opus 5 $0.00055 $0.03481
Sonnet 5 $0.00022 $0.01392
Haiku 4.5 $0.00011 $0.00696

Measured 11d ago against content hash 46c91091162e, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-10, from the pricing page.

Security

Grade A, and why

Gene Panel Selection Workflow scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 11d ago.

The scan reads SKILL.md. This mod also ships 1 executable file (scripts/gene_panel_helpers.py), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

pantheon/factory/templates/skills/omics/gene_panel_selection/SKILL.md · 673 lines

How it starts

The opening of the file, as written. The whole thing — 673 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Gene Panel Selection Workflow

This skill is used when you need to construct biologically meaningful and algorithmically robust gene panels. You will receive context from the leaderagent , use this context and STRICLTY follow this Gene Panel Selection Workflow

Workflow Enforcement (MANDATORY)

Determine which stage of the workflow (Steps 1–5) is required for the current task, and STRICTLY follow the corresponding step(s).

Once a step is entered, all its mandatory sub-steps must be executed. No partial execution or silent degradation is allowed.

Workdir

Always work in the workdir provided by the leader agent.

Calling other agents

You can call other agents by using the call_agent(agent_name, instruction) function.

  • Call the browser_use agent for information collection: When you encounter software or biological knowledge you are not familiar with, call browser_use to search the web and collect the necessary information.

  • Call the system_manager agent for software environment installation: When you need to install software packages, call system_manager to install them.

  • Call the biologist agent for results interpretation: When you plot figures, compute a panel, or have intermediate results, call biologist to ask for interpretations and include them in your report.

  • Call the reporteragent when all the results are obtained, to make a well written pdf.

Visual understanding

Use the observe_images function in the file_manager toolset to examine images and figures. If a figure is not publication-quality, replot it.

Reporting

At the end of the task, write a markdown report named:

report_analysis.md

The report must include:

  • Summary
  • Data (inputs, key parameters, outputs)
  • Results (figures + tables)
  • Key findings
  • Next steps

Large datasets

If the dataset is large, perform smart downsampling while preserving all cell types.


Gene Panel Selection Hyperparameters

Read the full file on GitHub · 673 lines

Files

What ships with it

1 file beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 11d ago First seen · 673 lines · 110 tokens per session scan A 46c91091162e

Subscribe to this mod's changes

Gene Panel Selection Workflow is a skill published in the GitHub repository aristoteleo/PantheonOS (485 stars, last pushed today), licensed BSD-2-Clause. It adds 110 tokens to every session and 6,961 once invoked, about $0.0006 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

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