clinical-trial

clinical-trial is a skill for Claude Code, Codex from beita6969/ScienceClaw. It costs 50 tokens per session (702 once invoked), scanned A, original, MIT.

A guide for planning and analyzing clinical trials, including randomized controlled trials, which compare treatments using assigned groups. It covers study size, outcomes, treatment assignment, reporting, and interim checks.

In plain words
What is it for?
Use it to plan Phase I–IV trials, choose primary and secondary outcomes, calculate sample size, design randomization and blinding, plan interim analyses, and prepare CONSORT reports.
Why use it?
It helps turn a medical research question into a structured study plan and supports decisions about how participants are assigned and how results are evaluated.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to plan Phase I–IV trials, choose primary and secondary outcomes, calculate sample size, design randomization and blinding, plan interim analyses, and prepare CONSORT reports.

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Install with agentmods
npx agentmods add skills/beita6969/scienceclaw/clinical-trial
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add beita6969/ScienceClaw --skill clinical-trial
Clone the repo
git clone --depth 1 https://github.com/beita6969/ScienceClaw

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for clinical-trial

README.md
[![agentmods](https://agentmods.dev/badge/skills/beita6969/scienceclaw/clinical-trial/github.svg)](https://agentmods.dev/skills/beita6969/scienceclaw/clinical-trial)
Your own site
<a href="https://agentmods.dev/skills/beita6969/scienceclaw/clinical-trial"><img src="https://agentmods.dev/badge/skills/beita6969/scienceclaw/clinical-trial/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for clinical-trial

Your own site · 80×15
<a href="https://agentmods.dev/skills/beita6969/scienceclaw/clinical-trial"><img src="https://agentmods.dev/badge/skills/beita6969/scienceclaw/clinical-trial.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 50 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 702 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00050 $0.00702
Opus 5 $0.00025 $0.00351
Sonnet 5 $0.00010 $0.00140
Haiku 4.5 $0.00005 $0.00070

Measured 12d ago against content hash 5c30feaf0633, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-11, from the pricing page.

Security

Grade A, and why

clinical-trial scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 12d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/clinical-trial/SKILL.md · 54 lines

How it starts

The opening of the file, as written. The whole thing — 54 lines — stays where its author put it; the contents beside it link to each section on GitHub.

When to Trigger

Activate this skill when the user mentions:

  • Clinical trial design, RCT, randomized controlled trial
  • Sample size calculation, power analysis for trials
  • CONSORT, STROBE, SPIRIT guidelines
  • Phase I, II, III, IV trials
  • Primary/secondary endpoints, composite endpoints
  • Interim analysis, adaptive trial design, futility
  • Blinding, randomization, allocation concealment
  • Intention-to-treat (ITT), per-protocol analysis

Step-by-Step Methodology

  1. Define the research question - Specify PICO (Population, Intervention, Comparator, Outcome). Determine if superiority, non-inferiority, or equivalence design is appropriate.
  2. Select trial phase and design - Choose phase (I: safety/dose, II: efficacy signal, III: confirmatory, IV: post-market). Consider parallel, crossover, factorial, or adaptive designs.
  3. Primary endpoint selection - Define primary outcome (must be clinically meaningful). Specify measurement timing and minimal clinically important difference (MCID).
  4. Sample size calculation - Specify alpha (typically 0.05, two-sided), power (typically 80-90%), expected effect size, and dropout rate. Use appropriate formula for the endpoint type (continuous, binary, time-to-event).
  5. Randomization and blinding - Recommend randomization method (simple, block, stratified, minimization). Specify blinding level (open-label, single, double, triple).
  6. Statistical analysis plan - Pre-specify primary analysis method (t-test, chi-square, log-rank, mixed models). Define interim analysis schedule with alpha-spending function (O'Brien-Fleming, Lan-DeMets).
  7. Reporting - Follow CONSORT for RCTs, STROBE for observational, SPIRIT for protocols. Include flow diagram, enrollment numbers, and all pre-specified analyses.

Key Databases and Tools

  • ClinicalTrials.gov - Trial registration and results
  • Cochrane Library - Systematic reviews of trials
  • FDA / EMA guidance documents - Regulatory requirements
  • nQuery / PASS / G*Power - Sample size software
  • CONSORT / SPIRIT checklists - Reporting standards

Read the full file on GitHub · 54 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 12d ago First seen · 54 lines · 50 tokens per session scan A 5c30feaf0633

Subscribe to this mod's changes

clinical-trial is a skill published in the GitHub repository beita6969/ScienceClaw (898 stars, last pushed 3mo ago), licensed MIT. It adds 50 tokens to every session and 702 once invoked, about $0.0003 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

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