synthetic-sciences/openscience is an AI workbench that carries out scientific research by reading papers, forming hypotheses, writing and running code, conducting experiments, analyzing results, and preparing reports. Researchers use it for work in machine learning, biology, physics, and chemistry with remote or local models. Catalogue add-ons extend its scientific workflows through skills and instructions.
Getting it into your agent
One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.
npx skills add synthetic-sciences/openscience --skill biopythongit clone --depth 1 https://github.com/synthetic-sciences/openscienceWrote this? Show the measurements
A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.
[](https://agentmods.dev/skills/synthetic-sciences/openscience/biopython)<a href="https://agentmods.dev/skills/synthetic-sciences/openscience/biopython"><img src="https://agentmods.dev/badge/skills/synthetic-sciences/openscience/biopython/github.svg" alt="Measured on agentmods" height="20"></a>Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.
<a href="https://agentmods.dev/skills/synthetic-sciences/openscience/biopython"><img src="https://agentmods.dev/badge/skills/synthetic-sciences/openscience/biopython.svg" alt="Reviewed on agentmods" width="80" height="20"></a>- NVIDIA SkillSpector pass
What it costs to keep this loaded
Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.
| Model | Per session | Once invoked |
|---|---|---|
| Fable 5.1 | $0.00076 | $0.03496 |
| Opus 5.5 | $0.00030 | $0.01398 |
| Sonnet 5.5 | $0.00015 | $0.00699 |
| Haiku 4.5 | $0.00008 | $0.00350 |
Grade A, and why
biopython scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 29d ago.
A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.
Nothing flagged
None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.
Copies of this mod
8 near-identical copies found in the catalogue:
- alterlab-biopython — 97% identical, 98 lines differ
- biopython — 92% identical, 19 lines differ
- biopython — 92% identical, 17 lines differ
- biopython — 92% identical, 16 lines differ
- biopython — 92% identical, 42 lines differ
- biopython — 92% identical, 13 lines differ
- biopython — 91% identical, 11 lines differ
- biopython — 91% identical, 11 lines differ
How it starts
The opening of the file, as written. The whole thing — 453 lines — stays where its author put it; the contents beside it link to each section on GitHub.
Biopython: Computational Molecular Biology in Python
Overview
Biopython is a comprehensive set of freely available Python tools for biological computation. It provides functionality for sequence manipulation, file I/O, database access, structural bioinformatics, phylogenetics, and many other bioinformatics tasks. The current version is Biopython 1.85 (released January 2025), which supports Python 3 and requires NumPy.
When to Use This Skill
Use this skill when:
- Working with biological sequences (DNA, RNA, or protein)
- Reading, writing, or converting biological file formats (FASTA, GenBank, FASTQ, PDB, mmCIF, etc.)
- Accessing NCBI databases (GenBank, PubMed, Protein, Gene, etc.) via Entrez
- Running BLAST searches or parsing BLAST results
- Performing sequence alignments (pairwise or multiple sequence alignments)
- Analyzing protein structures from PDB files
- Creating, manipulating, or visualizing phylogenetic trees
- Finding sequence motifs or analyzing motif patterns
- Calculating sequence statistics (GC content, molecular weight, melting temperature, etc.)
- Performing structural bioinformatics tasks
- Working with population genetics data
- Any other computational molecular biology task
Core Capabilities
Biopython is organized into modular sub-packages, each addressing specific bioinformatics domains:
- Sequence Handling - Bio.Seq and Bio.SeqIO for sequence manipulation and file I/O
- Alignment Analysis - Bio.Align and Bio.AlignIO for pairwise and multiple sequence alignments
- Database Access - Bio.Entrez for programmatic access to NCBI databases
- BLAST Operations - Bio.Blast for running and parsing BLAST searches
- Structural Bioinformatics - Bio.PDB for working with 3D protein structures
- Phylogenetics - Bio.Phylo for phylogenetic tree manipulation and visualization
- Advanced Features - Motifs, population genetics, sequence utilities, and more
Installation and Setup
Install Biopython using pip (requires Python 3 and NumPy):
What ships with it
7 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.
What this file has done since we first saw it
Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.
- 29d ago Changed · +6 lines 3d22fe01ad9c
- 1mo ago First seen · 447 lines · 76 tokens per session scan A 80511e547484
biopython is a skill published in the GitHub repository synthetic-sciences/openscience (4,004 stars, last pushed 3d ago), licensed Apache-2.0. It adds 76 tokens to every session and 3,496 once invoked, about $0.0003 per session on Opus 5.5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.
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