protein-structure

protein-structure is a skill for Claude Code, Codex from beita6969/ScienceClaw. It costs 53 tokens per session (740 once invoked), scanned A, original, MIT.

A guide for analyzing three-dimensional protein structures and studying how proteins fold, bind molecules, and interact.

In plain words
What is it for?
Use it to work with PDB files, predict or retrieve structures, assess model quality, identify binding sites, compare structures, and study protein-ligand or protein-protein interactions.
Why use it?
It helps interpret structural biology data and assess predicted or experimentally determined protein models.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to work with PDB files, predict or retrieve structures, assess model quality, identify binding sites, compare structures, and study protein-ligand or protein-protein interactions.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/beita6969/scienceclaw/protein-structure
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add beita6969/ScienceClaw --skill protein-structure
Clone the repo
git clone --depth 1 https://github.com/beita6969/ScienceClaw

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for protein-structure

README.md
[![agentmods](https://agentmods.dev/badge/skills/beita6969/scienceclaw/protein-structure/github.svg)](https://agentmods.dev/skills/beita6969/scienceclaw/protein-structure)
Your own site
<a href="https://agentmods.dev/skills/beita6969/scienceclaw/protein-structure"><img src="https://agentmods.dev/badge/skills/beita6969/scienceclaw/protein-structure/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for protein-structure

Your own site · 80×15
<a href="https://agentmods.dev/skills/beita6969/scienceclaw/protein-structure"><img src="https://agentmods.dev/badge/skills/beita6969/scienceclaw/protein-structure.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 53 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 740 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00053 $0.00740
Opus 5 $0.00026 $0.00370
Sonnet 5 $0.00011 $0.00148
Haiku 4.5 $0.00005 $0.00074

Measured 9d ago against content hash 38806ec61d2e, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-12, from the pricing page.

Security

Grade A, and why

protein-structure scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 9d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/protein-structure/SKILL.md · 54 lines

How it starts

The opening of the file, as written. The whole thing — 54 lines — stays where its author put it; the contents beside it link to each section on GitHub.

When to Trigger

Activate this skill when the user mentions:

  • Protein folding, AlphaFold, ESMFold, RoseTTAFold
  • PDB files, structural analysis, Ramachandran plots
  • Molecular docking, binding affinity, binding pockets
  • Homology modeling, threading, ab initio structure prediction
  • Protein-protein interactions (PPI), interface analysis
  • Structural alignment, RMSD, TM-score
  • Cryo-EM, X-ray crystallography data interpretation

Step-by-Step Methodology

  1. Retrieve or predict structure - Search PDB for experimental structures (by UniProt ID or gene name). If unavailable, use AlphaFold DB or run ESMFold. Check pLDDT confidence scores for predicted structures.
  2. Quality assessment - For experimental structures: check resolution, R-free, and completeness. For predictions: evaluate pLDDT per-residue and PAE (predicted aligned error) matrices.
  3. Structural analysis - Identify secondary structure elements (helices, sheets, loops). Compute solvent-accessible surface area. Map conserved residues and functional domains.
  4. Binding site identification - Use fpocket, SiteMap, or DoGSiteScorer for pocket detection. Cross-reference with known ligand binding from PDBe or BindingDB.
  5. Molecular docking - Recommend AutoDock Vina, GNINA, or Glide. Define grid box around binding site. Report binding energy (kcal/mol) and key interactions (H-bonds, hydrophobic, pi-stacking).
  6. Structural comparison - Align structures using TM-align or FATCAT. Report RMSD and TM-score. Identify conformational changes between states.
  7. Visualization guidance - Recommend PyMOL, ChimeraX, or Mol* for rendering. Specify coloring schemes (by chain, B-factor, electrostatics, or conservation).

Key Databases and Tools

  • PDB / PDBe - Experimental protein structures
  • AlphaFold DB - AI-predicted structures for UniProt entries
  • UniProt - Protein sequences, domains, and annotations
  • InterPro / Pfam - Domain classification
  • BindingDB / ChEMBL - Binding affinity data
  • RCSB PDB REST API - Programmatic structure queries
  • PDBe-KB - Aggregated structural annotations

Read the full file on GitHub · 54 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 9d ago First seen · 54 lines · 53 tokens per session scan A 38806ec61d2e

Subscribe to this mod's changes

protein-structure is a skill published in the GitHub repository beita6969/ScienceClaw (898 stars, last pushed 3mo ago), licensed MIT. It adds 53 tokens to every session and 740 once invoked, about $0.0003 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.

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