pubchem-compound

pubchem-compound is a skill for Claude Code, Codex from beita6969/ScienceClaw. It costs 82 tokens per session (1,480 once invoked), scanned A, original, MIT.

A search and retrieval tool for PubChem, a public database of chemical compounds and their properties.

In plain words
What is it for?
Use it to find compounds, retrieve molecular properties and 2D or 3D structures, and run similarity, substructure, or bioactivity searches.
Why use it?
It avoids manually searching chemical records and supports consistent lookups using names, database IDs, or molecular structure formats.

Skill for Claude CodeCodex

Which agent this was written for is unclear — built for openclaw. Also seen: built for openclaw.

Good fit Use it to find compounds, retrieve molecular properties and 2D or 3D structures, and run similarity, substructure, or bioactivity searches.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/beita6969/scienceclaw/pubchem-compound
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add beita6969/ScienceClaw --skill pubchem-compound
Clone the repo
git clone --depth 1 https://github.com/beita6969/ScienceClaw

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for pubchem-compound

README.md
[![agentmods](https://agentmods.dev/badge/skills/beita6969/scienceclaw/pubchem-compound/github.svg)](https://agentmods.dev/skills/beita6969/scienceclaw/pubchem-compound)
Your own site
<a href="https://agentmods.dev/skills/beita6969/scienceclaw/pubchem-compound"><img src="https://agentmods.dev/badge/skills/beita6969/scienceclaw/pubchem-compound/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for pubchem-compound

Your own site · 80×15
<a href="https://agentmods.dev/skills/beita6969/scienceclaw/pubchem-compound"><img src="https://agentmods.dev/badge/skills/beita6969/scienceclaw/pubchem-compound.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 82 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,480 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 1 finding. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00082 $0.01480
Opus 5 $0.00041 $0.00740
Sonnet 5 $0.00016 $0.00296
Haiku 4.5 $0.00008 $0.00148

Measured 9d ago against content hash b8911620ef38, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-12, from the pricing page.

Security

Grade A, and why

pubchem-compound scanned grade A with 1 finding against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 9d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Makes network callslowCapability

Not a fault in itself. Listed so you know the mod talks to something, and to what.

metadata: { "openclaw": { "emoji": "\u2697\ufe0f", "requires": { "bins": ["curl"] } } }
skills/pubchem-compound/SKILL.md · 125 lines

How it starts

The opening of the file, as written. The whole thing — 125 lines — stays where its author put it; the contents beside it link to each section on GitHub.

PubChem Compound Lookup

Query the PubChem PUG REST API to search over 110 million chemical compounds by name, CID, SMILES, InChI, or molecular formula. Retrieve molecular properties, 2D/3D structures, bioactivity data, and perform similarity or substructure searches.

API Base URL

https://pubchem.ncbi.nlm.nih.gov/rest/pug

API Endpoints

Compound Lookup

Retrieve compound data by name, CID, or SMILES:

# By compound name
curl -s "https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/name/aspirin/JSON" | head -60

# By PubChem CID
curl -s "https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/cid/2244/JSON" | head -60

# By SMILES string
curl -s "https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/smiles/CC(=O)OC1=CC=CC=C1C(=O)O/JSON" | head -60

# By InChI key
curl -s "https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/inchikey/BSYNRYMUTXBXSQ-UHFFFAOYSA-N/JSON" | head -60

Property Retrieval

Fetch specific molecular properties (comma-separated list):

# Common drug-likeness properties (Lipinski's Rule of Five)
curl -s "https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/name/ibuprofen/property/MolecularWeight,MolecularFormula,XLogP,HBondDonorCount,HBondAcceptorCount,TPSA/JSON"

# Multiple compounds by CID list
curl -s "https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/cid/2244,3672,2519/property/MolecularWeight,XLogP,IUPACName/JSON"

Available properties: MolecularFormula, MolecularWeight, CanonicalSMILES, IsomericSMILES, InChI, InChIKey, IUPACName, XLogP, ExactMass, MonoisotopicMass, TPSA, Complexity, HBondDonorCount, HBondAcceptorCount, RotatableBondCount, HeavyAtomCount, AtomStereoCount, BondStereoCount, Volume3D.

Similarity Search

Find structurally similar compounds using 2D fingerprint Tanimoto similarity:

# Find compounds with >=90% similarity to aspirin
curl -s "https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/fastsimilarity_2d/smiles/CC(=O)OC1=CC=CC=C1C(=O)O/cids/JSON?Threshold=90"

# Similarity search returning properties
curl -s "https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/fastsimilarity_2d/cid/2244/property/MolecularWeight,XLogP,CanonicalSMILES/JSON?Threshold=85&MaxRecords=10"

Read the full file on GitHub · 125 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 9d ago First seen · 125 lines · 82 tokens per session scan A b8911620ef38

Subscribe to this mod's changes

pubchem-compound is a skill published in the GitHub repository beita6969/ScienceClaw (898 stars, last pushed 3mo ago), licensed MIT. It adds 82 tokens to every session and 1,480 once invoked, about $0.0004 per session on Opus 5. A static security scan graded it A with 1 finding (makes network calls). No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.

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