togomcp: Skill for Claude Code

.claude/skills/disease-analysis/SKILL.md

disease-analysis is a skill for Claude Code from dbcls/togomcp. It costs 149 tokens per session (2,502 once invoked), scanned A, original, MIT.

A workflow for explaining a disease from its molecular changes through biological pathways and finally to clinical symptoms, using structured databases and literature sources.

In plain words
What is it for?
It is for studying disease mechanisms, associated proteins and pathways, symptoms, and possible drugs or targets.
Why use it?
It organizes information across different levels of biology so the explanation is based on linked evidence rather than isolated facts.

Skill for Claude Code

Written for Claude Code: installed under .claude/. Also seen: mentions Claude Code.

This is dbcls/togomcp's own configuration. It tells Claude Code how to work on togomcp itself, so it is not a mod to install elsewhere. Copy it as a starting point and replace the rules that are about this project. Everything togomcp configures →

Reuse

Borrowing it

Nothing to install: this file belongs to dbcls/togomcp. Take a copy, put it at the same path in your own repository, and replace the rules that are about this project with yours.

Copy the file
curl -O https://raw.githubusercontent.com/dbcls/togomcp/main/.claude/skills/disease-analysis/SKILL.md
Clone the repo
git clone --depth 1 https://github.com/dbcls/togomcp

Made for: Claude Code.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for disease-analysis

README.md
[![agentmods](https://agentmods.dev/badge/skills/dbcls/togomcp/disease-analysis.svg)](https://agentmods.dev/skills/dbcls/togomcp/disease-analysis)
Your own site
<a href="https://agentmods.dev/skills/dbcls/togomcp/disease-analysis"><img src="https://agentmods.dev/badge/skills/dbcls/togomcp/disease-analysis.svg" alt="Measured on agentmods" height="20"></a>
Per session 149 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 2,502 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00149 $0.02502
Opus 5 $0.00075 $0.01251
Sonnet 5 $0.00030 $0.00500
Haiku 4.5 $0.00015 $0.00250

Measured 8d ago against content hash 1b9471aa54e1, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-08, from the pricing page.

Security

Grade A, and why

disease-analysis scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 8d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

.claude/skills/disease-analysis/SKILL.md · 175 lines

How it starts

The opening of the file, as written. The whole thing — 175 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Disease Analysis (multi-scale, TogoMCP-driven)

Systematic analysis of any disease from molecular defect to clinical symptom, built from structured queries (not model recall). The driver is the TogoMCP MCP tools (run_sparql, togoid_convertId, togoid_countId) plus OLS4 and PubMed.

The full prompt template, output format, and per-disease-category customizations live in references/disease_analysis.md — read it for the deliverable structure. This SKILL.md is the operational path: verified queries, the exact tool calls, and the traps.

Prerequisites

  • The TogoMCP MCP server connected to your client (e.g. Claude Desktop, Claude Code). Its run_sparql, togoid_*, search_*, and get_MIE_file tools are what drive this skill.
  • The OLS4 and PubMed MCP tools (used in Phase 1 and Phase 6).
  • Network access from those servers to rdfportal.org and api.togoid.dbcls.jp.

Warm-up check (confirm connectivity before trusting the workflow)

Before a full analysis, send one Phase-2 query and one TogoID conversion through the MCP tools and confirm both return rows — that proves the SPARQL endpoint and the TogoID API are both reachable and the patterns still resolve:

run_sparql(database="uniprot", sparql_query="""
PREFIX up: <http://purl.uniprot.org/core/>
PREFIX rdfs: <http://www.w3.org/2000/01/rdf-schema#>
SELECT DISTINCT ?protein WHERE {
  ?protein a up:Protein ; up:reviewed 1 ;
           up:organism <http://purl.uniprot.org/taxonomy/9606> ;
           up:annotation ?annot .
  ?annot a up:Disease_Annotation ; rdfs:comment ?c .
  ?c bif:contains "'osteoarthritis'"
} LIMIT 5""")
togoid_convertId(ids="P45452", route="uniprot,pdb")     → structures for MMP13

If either returns nothing, that step is broken (endpoint down, schema drift, or full-text index changed) — diagnose it (re-read the database's MIE via get_MIE_file) before running the analysis.

Run the analysis (the six phases, with verified tool calls)

Read the full file on GitHub · 175 lines

Files

What ships with it

1 file beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 8d ago First seen · 175 lines · 149 tokens per session scan A 1b9471aa54e1

Subscribe to this mod's changes

disease-analysis is a skill published in the GitHub repository dbcls/togomcp (13 stars, last pushed yesterday), licensed MIT. It adds 149 tokens to every session and 2,502 once invoked, about $0.0007 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

Related

Other skills, from other repositories

open-ontologies

AI-native ontology engineering using 50+ MCP tools backed by an in-memory Oxigraph triple store. Build, validate, query, and govern RDF/OWL ontologies with a generate-validate-iterate loop. Use when building ontologies, knowledge graphs, RDF data, SPARQL queries, BORO/4D modeling, SHACL validation, clinical…

fabio-rovai/open-ontologies · 110 tokens

single-cell-rna-qc

Performs quality control on single-cell RNA-seq data (.h5ad or .h5 files) using scverse best practices with MAD-based filtering and comprehensive visualizations. Use when users request QC analysis, filtering low-quality cells, assessing data quality, or following scverse/scanpy best practices for single-cell analysis.

Wide-Moat/open-computer-use · 72 tokens

sematyp

SemaTyP combines two data sources into a knowledge graph for drug discovery / repositioning.

QSong-github/DrugClaw · 0 tokens

TTD

Query the Therapeutic Target Database (TTD) for drug-target-disease interaction data. Use this skill when the user asks about therapeutic targets, drugs, diseases, or their relationships — including target-drug mappings, clinical status of drugs, disease indications, UniProt/gene associations, and pathway annotations.…

QSong-github/DrugClaw · 111 tokens

nsides-query

Query the nSIDES drug side effect databases (OnSIDES, OffSIDES, KidSIDES). Use whenever the user asks about drug adverse reactions, side effects, off-label safety signals, or pediatric drug safety for a given drug name.

QSong-github/DrugClaw · 54 tokens

cpic

The pair and recommendation tables use drugid (e.g. RxNorm:32968), not drug name. This script resolves drug names automatically via the /v1/drug table before querying.

QSong-github/DrugClaw · 0 tokens