gwas-catalog

gwas-catalog is a skill for Claude Code, Codex from exon-research/genomi. It costs 25 tokens per session (1,091 once invoked), scanned A, original, Apache-2.0.

A tool for checking reported links between genetic variants or genes and traits in the GWAS Catalog, a public database of genome-wide association studies. GWAS studies look for statistical relationships between DNA differences and observable traits.

In plain words
What is it for?
Use it to compare candidate variants or genes with phenotype associations, retrieve trait-to-gene records, and review the ancestry and source-field limits of that evidence.
Why use it?
It makes the source and limits of reported gene-trait associations clearer than treating an association as proof of an individual medical outcome.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to compare candidate variants or genes with phenotype associations, retrieve trait-to-gene records, and review the ancestry and source-field limits of that evidence.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/exon-research/genomi/gwas-catalog
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add exon-research/genomi --skill gwas-catalog
Clone the repo
git clone --depth 1 https://github.com/exon-research/genomi

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for gwas-catalog

README.md
[![agentmods](https://agentmods.dev/badge/skills/exon-research/genomi/gwas-catalog/github.svg)](https://agentmods.dev/skills/exon-research/genomi/gwas-catalog)
Your own site
<a href="https://agentmods.dev/skills/exon-research/genomi/gwas-catalog"><img src="https://agentmods.dev/badge/skills/exon-research/genomi/gwas-catalog/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for gwas-catalog

Your own site · 80×15
<a href="https://agentmods.dev/skills/exon-research/genomi/gwas-catalog"><img src="https://agentmods.dev/badge/skills/exon-research/genomi/gwas-catalog.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 25 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,091 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00025 $0.01091
Opus 5 $0.00013 $0.00545
Sonnet 5 $0.00005 $0.00218
Haiku 4.5 $0.00003 $0.00109

Measured 13d ago against content hash c814325fb904, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-12, from the pricing page.

Security

Grade A, and why

gwas-catalog scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 13d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/gwas-catalog/SKILL.md · 115 lines

How it starts

The opening of the file, as written. The whole thing — 115 lines — stays where its author put it; the contents beside it link to each section on GitHub.

GWAS Catalog Association Evidence

Use GWAS Catalog association records for supplied phenotypes plus candidate variants or genes.

For phenotype plus candidate genes, gwas.compare_gene_associations returns GWAS Catalog reported_gene, mapped_gene, or source gene-field association evidence. phenotype.retrieve_trait_gene_records retrieves native trait-to-gene records from integrated public sources, optionally filtered by gene. If another source prior is relevant, call that source-specific tool separately and keep the evidence regimes separate. HPO or single-subject phenotype matching belongs outside this skill.

Goal

Retrieve and compare GWAS Catalog association evidence with explicit source-field and phenotype-match limitations. Personal interpretation requires separate sample support and careful wording.

Convention: See skills/conventions/evidence-quality.md.

Cross-Capability Synthesis

A scope-limited result from this capability is not a final user-facing answer when other Genomi capabilities can contribute orthogonal evidence to the same question. Returning "cannot answer" while applicable capabilities remain unexamined is a host-agent failure mode.

Tools

gwas.compare_gene_associations

Compare candidate genes using GWAS Catalog reported_gene and mapped_gene trait-association evidence.

Use when: The user gives a phenotype or trait plus candidate genes and asks for GWAS Catalog gene-field association support.

Why necessary: GWAS Catalog gene fields are source annotations for population-trait associations; they should stay separate from causal-gene, HPO, or drug-target evidence.

Not for: causal-gene claims unless separate causal evidence is supplied.

Result semantics: Returns source-local GWAS Catalog gene-field association evidence only. reported_gene and mapped_gene are source annotations and are not causal-gene evidence. Causal-gene or effector-gene wording returns wrong_evidence_regime with a routing hint.

Read the full file on GitHub · 115 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 13d ago First seen · 115 lines · 25 tokens per session scan A c814325fb904

Subscribe to this mod's changes

gwas-catalog is a skill published in the GitHub repository exon-research/genomi (482 stars, last pushed 11d ago), licensed Apache-2.0. It adds 25 tokens to every session and 1,091 once invoked, about $0.0001 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

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