pharmacogenomics

pharmacogenomics is a skill for Claude Code, Codex from exon-research/genomi. It costs 54 tokens per session (2,627 once invoked), scanned A, original, Apache-2.0.

A research helper for pharmacogenomics, the study of how genes can affect medication response. It combines public drug–gene evidence with optional local genotype information when an approved genome index is selected.

In plain words
What is it for?
It helps review medication response, prescribing guidance, drug–gene and variant–drug findings, drug databases, and pharmacogene results.
Why use it?
It keeps general evidence about a drug or gene separate from claims about a particular person’s DNA.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit It helps review medication response, prescribing guidance, drug–gene and variant–drug findings, drug databases, and pharmacogene results.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/exon-research/genomi/pharmacogenomics
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add exon-research/genomi --skill pharmacogenomics
Clone the repo
git clone --depth 1 https://github.com/exon-research/genomi

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for pharmacogenomics

README.md
[![agentmods](https://agentmods.dev/badge/skills/exon-research/genomi/pharmacogenomics/github.svg)](https://agentmods.dev/skills/exon-research/genomi/pharmacogenomics)
Your own site
<a href="https://agentmods.dev/skills/exon-research/genomi/pharmacogenomics"><img src="https://agentmods.dev/badge/skills/exon-research/genomi/pharmacogenomics/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for pharmacogenomics

Your own site · 80×15
<a href="https://agentmods.dev/skills/exon-research/genomi/pharmacogenomics"><img src="https://agentmods.dev/badge/skills/exon-research/genomi/pharmacogenomics.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 54 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 2,627 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00054 $0.02627
Opus 5 $0.00027 $0.01314
Sonnet 5 $0.00011 $0.00525
Haiku 4.5 $0.00005 $0.00263

Measured 11d ago against content hash 2810541581a1, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-10, from the pricing page.

Security

Grade A, and why

pharmacogenomics scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 11d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/pharmacogenomics/SKILL.md · 222 lines

How it starts

The opening of the file, as written. The whole thing — 222 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Pharmacogenomics

Use this skill when the user asks about medication response, PGx guidelines, drug-gene or variant-drug evidence, PGxDB, ATC codes, DrugBank IDs, PharmCAT, or pharmacogene sample evidence.

Contract

  • Drug-response claims use public PGx source evidence.
  • Personal drug-response statements cite separate local genotype or PGx caller support.
  • External PGx lookups receive selected public targets only.
  • Source-backed PGx findings can be stored as shared reviewed research.
  • User-specific sample interpretations can be stored as private reviewed research.

Convention: See skills/conventions/evidence-quality.md. Convention: See skills/_output-rules.md.

Primary Flow

  1. Use pharmacogenomics.review_medication for ordinary medication questions. It combines ClinPGx, FDA PGx tables, PGxDB, stored reviewed research, and optional selected sample evidence in one bounded review.
  2. Inspect evidence_envelope, medication_review_matrix, evidence_matrix, target_inventory, answer_support, and unanswered_answer_components before answering. Treat each medication_review_matrix.rows[] entry as the review unit.
  3. If the answer needs source review beyond returned public records, use research.list_sources, review the selected public target, then store the finding with research.record.
  4. If the answer needs personal sample evidence, use the Active Genome Index only when selected or supplied in this chat. Confirm relevant alleles with variant.resolve or active_genome_index.classify_genotype_support.

Tool Choices

  • pharmacogenomics.review_medication: bounded medication evidence review; public-only by default, with Active Genome Index evidence when selected.
  • pharmacogenomics.fetch_clinpgx, pharmacogenomics.fetch_fda_labels, and pharmacogenomics.fetch_pgxdb: focused public PGx source retrieval when the medication review needs a source-specific follow-up.
  • pharmacogenomics.describe_gene_requirements: gene-specific sample evidence requirements for named allele matching, outside calls, HLA, MT-RNR1, G6PD, and SV/CNV-sensitive genes.
  • pharmacogenomics.check_pharmcat: check local PharmCAT availability.
  • pharmacogenomics.preflight_pharmcat: inspect whether the selected Active Genome Index can provide a suitable PharmCAT input before running it.
  • pharmacogenomics.prepare_outside_call_tsv and pharmacogenomics.validate_outside_call_tsv: prepare or validate specialized outside-call evidence for PharmCAT.
  • pharmacogenomics.run_pharmcat: run broad PharmCAT calling from the selected Active Genome Index and return provenance plus sample_pgx_matrix rows projected from report, phenotype, calls-only, and matcher artifacts.
  • pharmacogenomics.import_pharmcat_artifacts: import existing PharmCAT JSON, TSV, matcher, phenotype, missing-position, or output-directory artifacts and return sample_pgx_matrix.

Read the full file on GitHub · 222 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 11d ago First seen · 222 lines · 54 tokens per session scan A 2810541581a1

Subscribe to this mod's changes

pharmacogenomics is a skill published in the GitHub repository exon-research/genomi (482 stars, last pushed 10d ago), licensed Apache-2.0. It adds 54 tokens to every session and 2,627 once invoked, about $0.0003 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

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