bio-fasta-database-curator

bio-fasta-database-curator is a skill for Claude Code from fmschulz/omics-skills. It costs 52 tokens per session (2,157 once invoked), scanned A, original, MIT.

A tool for cleaning and validating FASTA or FAA sequence databases, which store DNA, RNA, or protein sequences with descriptive headers.

In plain words
What is it for?
It helps merge databases, convert GenBank files, standardize taxonomy labels, produce statistics, and prepare inputs for BLAST, MMseqs2, or HMM searches.
Why use it?
It removes inconsistent headers, duplicate sequences, format problems, and conflicts that can make later searches unreliable.

Skill for Claude Code

Written for Claude Code: shipped in a Claude Code plugin.

Part of the omics-skills plugin — 34 skills, 4 agents shipped together

Good fit It helps merge databases, convert GenBank files, standardize taxonomy labels, produce statistics, and prepare inputs for BLAST, MMseqs2, or HMM searches.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/fmschulz/omics-skills/bio-fasta-database-curator
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add fmschulz/omics-skills --skill bio-fasta-database-curator
Clone the repo
git clone --depth 1 https://github.com/fmschulz/omics-skills

Made for: Claude Code.

Or install omics-skills, the plugin that ships this one along with the rest of its 34 skills, 4 agents.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for bio-fasta-database-curator

README.md
[![agentmods](https://agentmods.dev/badge/skills/fmschulz/omics-skills/bio-fasta-database-curator/github.svg)](https://agentmods.dev/skills/fmschulz/omics-skills/bio-fasta-database-curator)
Your own site
<a href="https://agentmods.dev/skills/fmschulz/omics-skills/bio-fasta-database-curator"><img src="https://agentmods.dev/badge/skills/fmschulz/omics-skills/bio-fasta-database-curator/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for bio-fasta-database-curator

Your own site · 80×15
<a href="https://agentmods.dev/skills/fmschulz/omics-skills/bio-fasta-database-curator"><img src="https://agentmods.dev/badge/skills/fmschulz/omics-skills/bio-fasta-database-curator.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 52 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 2,157 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00052 $0.02157
Opus 5 $0.00026 $0.01078
Sonnet 5 $0.00010 $0.00431
Haiku 4.5 $0.00005 $0.00216

Measured 3d ago against content hash 282dd87ebaae, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-09, from the pricing page.

Security

Grade A, and why

bio-fasta-database-curator scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 3d ago.

The scan reads SKILL.md. This mod also ships 1 executable file (scripts/curate_fasta.py), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/bio-fasta-database-curator/SKILL.md · 261 lines

How it starts

The opening of the file, as written. The whole thing — 261 lines — stays where its author put it; the contents beside it link to each section on GitHub.

FASTA Database Curator

Overview

Automate the curation and standardization of biological sequence databases. This skill handles the tedious work of processing FASTA/FAA files, ensuring consistent header formats, removing duplicates, and preparing databases for downstream analysis.

Supplementary version-grounded tool notes: tools.md.

Key Capabilities:

  • Header format standardization (pipe separators, prefixes)
  • Duplicate detection and removal (by sequence or ID)
  • Format conversion (GenBank → FASTA, multi-line → single-line)
  • Database merging with conflict resolution
  • Statistics generation (counts, lengths, taxonomy, GC content)
  • Validation (no whitespace in headers, proper formatting)
  • Taxonomy label extraction and standardization

When to Use This Skill

Use this skill when:

  • User needs to standardize sequence headers
  • User wants to merge multiple FASTA files
  • User needs to remove duplicate sequences
  • User is preparing a database for HMM/BLAST/MMseqs2
  • User wants database statistics and quality metrics
  • User needs to convert between sequence formats

Header Format Standards

Recommended Format

Use pipe-separated fields with consistent prefixes:

>PREFIX|ACCESSION|DESCRIPTION
SEQUENCE...

Examples:

>VP|Mavirus_MCP|Major capsid protein [Virophage]
>PLV|NC_021333_1|Polinton-like virus hypothetical protein
>NCLDV|YP_009173877.1|DNA polymerase [Marseilleviridae]

Common Transformations

# Remove whitespace from headers
old: ">VP_MCP Mavirus major capsid protein"
new: ">VP_MCP|Mavirus_major_capsid_protein"

# Add taxonomy prefix
old: ">NC_021333.1 hypothetical protein"
new: ">PLV|NC_021333.1|hypothetical_protein"

# Standardize separators
old: ">seq1 [organism=Virus] protein"
new: ">seq1|Virus|protein"

Quick Reference

Task Action
Inspect database Count records, sample headers, check whitespace and length distribution before changing anything.
Standardize headers Define deterministic transformation rules and preserve original-to-new ID mapping.
Merge or deduplicate Decide whether duplicates are removed by ID, sequence, or both, then report what changed.
Validate output Re-count records, verify FASTA syntax, and write database statistics.
Run the bundled curator uv run --script skills/bio-fasta-database-curator/scripts/curate_fasta.py input.fasta --output curated.fasta --prefix REF --deduplicate both

Read the full file on GitHub · 261 lines

Files

What ships with it

3 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 3d ago Changed 282dd87ebaae
  2. 9d ago First seen · 261 lines · 52 tokens per session scan A 47bcbc6a6578

Subscribe to this mod's changes

bio-fasta-database-curator is a skill published in the GitHub repository fmschulz/omics-skills (7 stars, last pushed 4d ago), licensed MIT. It adds 52 tokens to every session and 2,157 once invoked, about $0.0003 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-31.

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