bio-logic

bio-logic is a skill for Claude Code from fmschulz/omics-skills. It costs 39 tokens per session (2,056 once invoked), scanned A, original, MIT.

A framework for checking scientific claims, study methods, bias, and the strength of supporting evidence.

In plain words
What is it for?
Critiquing papers, evaluating study designs and analyses, assessing causal claims, and revising hypotheses during exploratory work.
Why use it?
It helps separate what a study shows from what it merely suggests, while identifying missing tests and alternative explanations.

Skill for Claude Code

Written for Claude Code: shipped in a Claude Code plugin.

Part of the omics-skills plugin — 34 skills, 4 agents shipped together

Good fit Critiquing papers, evaluating study designs and analyses, assessing causal claims, and revising hypotheses during exploratory work.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/fmschulz/omics-skills/bio-logic
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add fmschulz/omics-skills --skill bio-logic
Clone the repo
git clone --depth 1 https://github.com/fmschulz/omics-skills

Made for: Claude Code.

Or install omics-skills, the plugin that ships this one along with the rest of its 34 skills, 4 agents.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for bio-logic

README.md
[![agentmods](https://agentmods.dev/badge/skills/fmschulz/omics-skills/bio-logic.svg)](https://agentmods.dev/skills/fmschulz/omics-skills/bio-logic)
Your own site
<a href="https://agentmods.dev/skills/fmschulz/omics-skills/bio-logic"><img src="https://agentmods.dev/badge/skills/fmschulz/omics-skills/bio-logic.svg" alt="Measured on agentmods" height="20"></a>
Per session 39 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 2,056 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00039 $0.02056
Opus 5 $0.00019 $0.01028
Sonnet 5 $0.00008 $0.00411
Haiku 4.5 $0.00004 $0.00206

Measured 2d ago against content hash 1479dc270eab, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-08, from the pricing page.

Security

Grade A, and why

bio-logic scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 2d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/bio-logic/SKILL.md · 231 lines

How it starts

The opening of the file, as written. The whole thing — 231 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Bio-Logic: Scientific Reasoning Evaluation

Use structured frameworks to evaluate scientific claims, methodology, and evidence strength.

Instructions

  1. Identify the task (claim assessment, paper critique, study design review, project interpretation, or hypothesis revision).
  2. For project work, maintain a hypothesis register with at least 5 distinct active hypotheses until the project is no longer exploratory.
  3. After each major intermediate result, reflect on what changed, revise hypothesis status, and identify the next discriminating check.
  4. When findings need context, pair this reasoning with a literature-search skill such as /polars-dovmed, then revise hypotheses against the literature.
  5. Select the study-type profile before applying a checklist. Do not grade a computational benchmark, phylogenetic analysis, or evolutionary inference as if it were an intervention trial.
  6. Structure output using the provided format.

Study-Type Profiles

Profile Main evidence checks Rating language
Intervention allocation, controls, adherence, attrition, estimand, harms GRADE when the review question and evidence synthesis support it
Observational or quasi-experimental identification assumptions, temporality, confounding, negative controls, sensitivity analyses risk-of-bias plus causal-confidence statement
Computational or machine learning data provenance, leakage, splits, baselines, calibration, external validation, reproducibility computational evidence confidence
Evolutionary or comparative genomics orthology, taxon/reference sampling, model fit, support, contamination, topology sensitivity phylogenetic/comparative evidence confidence
Descriptive or exploratory omics sampling, measurement, multiple testing, effect sizes, replication, alternative explanations descriptive confidence; avoid causal labels

Project Hypothesis Loop

Use this loop for omics projects, unexpected results, exploratory analyses, and any request that asks what results mean.

Read the full file on GitHub · 231 lines

Files

What ships with it

7 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 2d ago Changed · +7 tokens per session 1479dc270eab
  2. 8d ago First seen · 231 lines · 32 tokens per session scan A 1e130aaf8b01

Subscribe to this mod's changes

bio-logic is a skill published in the GitHub repository fmschulz/omics-skills (7 stars, last pushed 2d ago), licensed MIT. It adds 39 tokens to every session and 2,056 once invoked, about $0.0002 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-31.

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