bio-prefect-dask-nextflow

bio-prefect-dask-nextflow is a skill for Claude Code from fmschulz/omics-skills. It costs 37 tokens per session (550 once invoked), scanned A, original, MIT.

A guide for designing reproducible bioinformatics pipelines with Prefect and Dask, Nextflow, or both. These tools coordinate multi-step analyses locally, across computers, or on an HPC cluster.

In plain words
What is it for?
Scaffolding local, distributed, cloud, or Slurm-based workflows and preparing runnable layouts with data paths, resources, and execution settings.
Why use it?
It helps match the workflow engine to the scheduler, containers, data size, and computing environment, then checks that the pipeline can test, retry, and resume.

Skill for Claude Code

Written for Claude Code: shipped in a Claude Code plugin.

Part of the omics-skills plugin — 34 skills, 4 agents shipped together

Good fit Scaffolding local, distributed, cloud, or Slurm-based workflows and preparing runnable layouts with data paths, resources, and execution settings.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/fmschulz/omics-skills/bio-prefect-dask-nextflow
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add fmschulz/omics-skills --skill bio-prefect-dask-nextflow
Clone the repo
git clone --depth 1 https://github.com/fmschulz/omics-skills

Made for: Claude Code.

Or install omics-skills, the plugin that ships this one along with the rest of its 34 skills, 4 agents.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for bio-prefect-dask-nextflow

README.md
[![agentmods](https://agentmods.dev/badge/skills/fmschulz/omics-skills/bio-prefect-dask-nextflow/github.svg)](https://agentmods.dev/skills/fmschulz/omics-skills/bio-prefect-dask-nextflow)
Your own site
<a href="https://agentmods.dev/skills/fmschulz/omics-skills/bio-prefect-dask-nextflow"><img src="https://agentmods.dev/badge/skills/fmschulz/omics-skills/bio-prefect-dask-nextflow/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for bio-prefect-dask-nextflow

Your own site · 80×15
<a href="https://agentmods.dev/skills/fmschulz/omics-skills/bio-prefect-dask-nextflow"><img src="https://agentmods.dev/badge/skills/fmschulz/omics-skills/bio-prefect-dask-nextflow.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 37 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 550 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00037 $0.00550
Opus 5 $0.00018 $0.00275
Sonnet 5 $0.00007 $0.00110
Haiku 4.5 $0.00004 $0.00055

Measured 10d ago against content hash 9692b1a7168f, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-10, from the pricing page.

Security

Grade A, and why

bio-prefect-dask-nextflow scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 10d ago.

The scan reads SKILL.md. This mod also ships 1 executable file (scripts/submit_nextflow.sh), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/bio-prefect-dask-nextflow/SKILL.md · 66 lines

How it starts

The opening of the file, as written. The whole thing — 66 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Bio Prefect + Dask + Nextflow

Choose and scaffold the right workflow engine for local, distributed, or HPC bioinformatics pipelines.

Supplementary docs last verified: 2026-05-30. Current source checks cover Prefect 3.7.2, Dask/distributed 2026.3.0, prefect-dask v0.2.6 (archived repository; install through prefect[dask]), and Nextflow v26.04.3.

Instructions

  1. Collect requirements (scheduler, container policy, data location, scale).
  2. Choose engine: Prefect+Dask, Nextflow, or Hybrid.
  3. Generate a runnable scaffold with clear data layout and resources.
  4. Validate with a small test and resume/retry checks.

Quick Reference

Task Action
Engine choice See decision-matrix.md
Prefect+Dask scaffold See prefect-dask.md
Prefect on Slurm See prefect-hpc-slurm.md
Nextflow on HPC See nextflow-hpc.md
Submit Nextflow through Slurm SLURM_ACCOUNT=... scripts/submit_nextflow.sh main.nf 'data/*.fastq.gz' results
Examples See examples.md

Input Requirements

  • Workflow requirements and steps
  • Target environment (local, cluster, cloud)
  • Scheduler and container constraints
  • Data locations and expected volumes

Output

  • Engine recommendation with rationale
  • Runnable scaffold (files + commands)
  • Resource plan per step
  • Validation plan and checkpoints

Quality Gates

  • Tiny test run completes end-to-end
  • Resume/retry behavior verified
  • Resource plan matches cluster limits
  • Temporary Dask clusters are created by the task runner at flow runtime and closed with the flow
  • Compound FASTQ suffixes do not leak into sample output names
  • Nextflow launch runs through sbatch and verifies trace and non-empty result artifacts

Examples

Example 1: Engine recommendation

Choice: Nextflow
Why: CLI-heavy pipeline, HPC scheduler required, reproducible cache/resume needed.

Troubleshooting

Issue: Workflow fails on HPC due to environment mismatch Solution: Pin container/conda versions and validate with a minimal test dataset.

Read the full file on GitHub · 66 lines

Files

What ships with it

7 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 10d ago First seen · 66 lines · 37 tokens per session scan A 9692b1a7168f

Subscribe to this mod's changes

bio-prefect-dask-nextflow is a skill published in the GitHub repository fmschulz/omics-skills (7 stars, last pushed 4d ago), licensed MIT. It adds 37 tokens to every session and 550 once invoked, about $0.0002 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-31.

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