FridrichMethod/awesome-skills

Curated, auto-synced collection of 2,000+ Claude Code & Codex skills for AI4Protein, bioinformatics, AI development, and academic paper writing. One curl command installs them all.

14Stars on the repository
200Mods indexed here, across every type
3d agoLast push, which is what freshness is scored on
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ai-analyzer

25

FridrichMethod/awesome-skills

Skill Claude Code

An AI-based health analysis system that combines health data from multiple sources to find unusual patterns, assess health risks, answer questions, and create health reports.

not rated 14 3d ago A 46 tokens

ai-debt-detector

26

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Use after generating code, after accepting AI suggestions, or when reviewing AI-written modules. Also use when code works but feels brittle, when error handling seems thin, when orphaned resources or missing cleanup are suspected, or when the agent claims done but hidden debt may exist. Catches the specific failure…

not rated 14 3d ago A 74 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Regression testing strategies for AI-assisted development. Sandbox-mode API testing without database dependencies, automated bug-check workflows, and patterns to catch AI blind spots where the same model writes and reviews code.

not rated 14 3d ago A 42 tokens

ai-writing-detox

29

FridrichMethod/awesome-skills

Skill Codex

Eliminates AI-generated writing patterns that erode reader trust. Use when writing or editing articles, docs, or press releases.

not rated 14 3d ago A 31 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Build production Apache Airflow DAGs with best practices for operators, sensors, testing, and deployment. Use when creating data pipelines, orchestrating workflows, or scheduling batch jobs.

not rated 14 3d ago A 42 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

AiZynthFinder retrosynthetic route planning (CASP) from AstraZeneca Molecular AI. Monte Carlo tree search guided by a template-based neural expansion policy recursively disconnects a target SMILES until precursors are found in a purchasable stock. Covers config.yml (v4 format), aizynthcli batch screening, the…

not rated 14 3d ago A 167 tokens

algorithmic-art

32

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Creating algorithmic art using p5.js with seeded randomness and interactive parameter exploration. Use this when users request creating art using code, generative art, algorithmic art, flow fields, or particle systems. Create original algorithmic art rather than copying existing artists' work to avoid copyright…

not rated 14 3d ago A 62 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Trim PCR primers from aligned reads in amplicon-panel BAMs using samtools ampliconclip. Use when processing SARS-CoV-2 ARTIC, hereditary cancer panels, ctDNA hot-spot panels, or any amplicon assay where primer-derived bases would falsely confirm reference at primer footprints.

not rated 14 3d ago A 71 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Filter alignments by flags, mapping quality, and regions using samtools view and pysam. Use when extracting specific reads, removing low-quality alignments, or subsetting to target regions.

not rated 14 3d ago A 44 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Quantify transcript expression from FASTQ with Salmon (selective alignment) or kallisto (pseudoalignment), bypassing genome mapping. Use when quantifying RNA-seq without alignment, deciding whether a decoy-aware index is required, detecting and verifying library strandedness, enabling GC and sequence bias correction…

not rated 14 3d ago A 95 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Create and use BAI/CSI indices for BAM/CRAM files using samtools and pysam. Use when enabling random access to alignment files or fetching specific genomic regions.

not rated 14 3d ago A 41 tokens

bio-alignment-io

37

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Read, write, and convert multiple sequence alignment files using Biopython Bio.AlignIO. Supports Clustal, PHYLIP, Stockholm, FASTA, Nexus, and other alignment formats for phylogenetics and conservation analysis. Use when reading, writing, or converting alignment file formats.

not rated 14 3d ago A 64 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Sort alignment files by coordinate or read name using samtools and pysam. Use when preparing BAM files for indexing, variant calling, or paired-end analysis.

not rated 14 3d ago A 37 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Trim multiple sequence alignments using ClipKIT, trimAl, BMGE, Divvier, or HMMcleaner with mode selection guidance per downstream goal. Use when removing unreliable columns or contaminating residues before phylogenetic inference, HMM building, or selection analysis.

not rated 14 3d ago A 60 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Validate alignment quality with insert size distribution, proper pairing rates, GC bias, strand balance, and other post-alignment metrics. Use when verifying alignment data quality before variant calling or quantification.

not rated 14 3d ago A 43 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Detect allele-specific chromatin accessibility from ATAC-seq using WASP, GATK ASEReadCounter, or RASQUAL. Use when mapping cis-regulatory genetic variants from heterozygous SNPs, separating cis from trans regulation, building chromatin QTL (caQTL) maps, validating GWAS variant function with allelic imbalance, or…

not rated 14 3d ago A 93 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Detects allele-specific transcription factor or histone modification binding from heterozygous-variant ChIP-seq using WASP (reference-bias filter; mandatory upstream), RASQUAL (joint QTL + bias-corrected testing), BaalChIP (Bayesian beta-binomial with copy-number-aware overdispersion), and AlleleSeq (personalized…

not rated 14 3d ago A 150 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Infer integer allele-specific copy number, tumor purity, and ploidy from tumor sequencing by jointly modeling read depth (logR) and B-allele frequency (BAF) with ASCAT, Sequenza, FACETS, PURPLE, and PureCN (tumor-only). Covers the purity-ploidy identifiability problem, the diploid-baseline (dipLogR) anchor…

not rated 14 3d ago A 176 tokens

alpha-vantage

44

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Access real-time and historical stock market data, forex rates, cryptocurrency prices, commodities, economic indicators, and 50+ technical indicators via the Alpha Vantage API. Use when fetching stock prices (OHLCV), company fundamentals (income statement, balance sheet, cash flow), earnings, options data, market…

not rated 14 3d ago A 126 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Access AlphaFold DB's 200M+ predicted structures by UniProt ID. Download PDB/mmCIF, analyze pLDDT/PAE, bulk-fetch proteomes via Google Cloud. For experimental structures use PDB; for prediction use ColabFold or ESMFold.

not rated 14 3d ago A 65 tokens

alphafold-database

46

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Access AlphaFold's 200M+ AI-predicted protein structures. Retrieve structures by UniProt ID, download PDB/mmCIF files, analyze confidence metrics (pLDDT, PAE), for drug discovery and structural biology.

not rated 14 3d ago A 55 tokens

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Retrieves and interprets AlphaFold Protein Structure Database (AFDB) models by UniProt accession, reading pLDDT and PAE confidence correctly. Use when treating pLDDT as PER-RESIDUE confidence (not global accuracy) and recognizing a long low-pLDDT stretch as an intrinsically disordered region rather than a modeling…

not rated 14 3d ago A 195 tokens

alphafold

48

FridrichMethod/awesome-skills

Skill Claude CodeCodex

Validate protein designs using AlphaFold2 structure prediction. Use this skill when: (1) Validating designed sequences fold correctly, (2) Predicting binder-target complex structures, (3) Calculating confidence metrics (pLDDT, pTM, ipTM), (4) Self-consistency validation of designs, (5) Multi-chain complex prediction…

not rated 14 3d ago A 100 tokens

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