histolab

histolab is a skill for Claude Code, Codex from K-Dense-AI/scientific-agent-skills. It costs 65 tokens per session (2,234 once invoked), scanned A, original, MIT.

A Python library for processing whole-slide images, which are very large digital scans of microscope tissue slides. It detects tissue, cuts slides into smaller image tiles, and prepares them for analysis.

In plain words
What is it for?
Use it to detect tissue, extract tiles from pathology slides, normalize H&E stain appearance, prepare training data, and make quick tile-based analyses.
Why use it?
It removes much of the manual work involved in finding useful tissue regions and turning gigapixel slides into manageable datasets.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to detect tissue, extract tiles from pathology slides, normalize H&E stain appearance, prepare training data, and make quick tile-based analyses.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/k-dense-ai/scientific-agent-skills/histolab
About the project

Scientific Agent Skills is a collection of reusable procedures that give AI agents capabilities for scientific research across areas such as biology, chemistry, medicine, and drug discovery. It is used by researchers and by people building AI scientist workflows with compatible coding agents. The catalogue contains many of the project's skills and supporting instructions.

K-Dense-AI/scientific-agent-skills · 44,469 stars · on GitHub · arxiv.org

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add K-Dense-AI/scientific-agent-skills --skill histolab
Clone the repo
git clone --depth 1 https://github.com/K-Dense-AI/scientific-agent-skills

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for histolab

README.md
[![agentmods](https://agentmods.dev/badge/skills/k-dense-ai/scientific-agent-skills/histolab/github.svg)](https://agentmods.dev/skills/k-dense-ai/scientific-agent-skills/histolab)
Your own site
<a href="https://agentmods.dev/skills/k-dense-ai/scientific-agent-skills/histolab"><img src="https://agentmods.dev/badge/skills/k-dense-ai/scientific-agent-skills/histolab/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for histolab

Your own site · 80×15
<a href="https://agentmods.dev/skills/k-dense-ai/scientific-agent-skills/histolab"><img src="https://agentmods.dev/badge/skills/k-dense-ai/scientific-agent-skills/histolab.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 65 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 2,234 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • Socket pass 9 Apr 2026
  • Snyk pass 9 Apr 2026
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00065 $0.02234
Opus 5 $0.00032 $0.01117
Sonnet 5 $0.00013 $0.00447
Haiku 4.5 $0.00006 $0.00223

Measured 8d ago against content hash af4b9a0ab9de, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-11, from the pricing page.

Security

Grade A, and why

histolab scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 8d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

Origin

Copies of this mod

1 near-identical copy found in the catalogue:

  • histolab — 100% identical, 19 lines differ
skills/histolab/SKILL.md · 261 lines

How it starts

The opening of the file, as written. The whole thing — 261 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Histolab

Overview

Histolab is a Python library for processing whole slide images (WSI) in digital pathology. It automates tissue detection, extracts informative tiles from gigapixel images, and prepares datasets for deep learning pipelines. The library handles multiple WSI formats, implements sophisticated tissue segmentation, and provides flexible tile extraction strategies.

Installation

Install OpenSlide system libraries first (OpenSlide download), then install histolab:

uv pip install histolab

For built-in TCGA sample slides via histolab.data, also install pooch:

uv pip install pooch

Histolab 0.7.0 (latest stable) supports Python 3.8–3.11 on Linux and macOS. Windows is not supported as of 0.7.0.

Quick Start

Basic workflow for extracting tiles from a whole slide image:

from histolab.slide import Slide
from histolab.tiler import RandomTiler

# Load slide
slide = Slide("slide.svs", processed_path="output/")

# Configure tiler
tiler = RandomTiler(
    tile_size=(512, 512),
    n_tiles=100,
    level=0,
    seed=42
)

# Preview tile locations
tiler.locate_tiles(slide, n_tiles=20)

# Extract tiles
tiler.extract(slide)

Core Capabilities

Six capability areas, each with worked code, are documented in references/core_capabilities.md:

  1. Slide management — opening slides, properties, levels, thumbnails, and scaled images.
  2. Tissue detection and masksTissueMask and BiggestTissueBoxMask, and custom masks.
  3. Tile extraction — random, grid, and score-based tilers with size, level, and tissue-fraction control.
  4. Filters and preprocessing — image and morphological filters, and composing them.
  5. Stain normalization — Reinhard and Macenko normalization against a target image.
  6. Visualization — locating tiles on the slide and inspecting masks and extractions.

Five end-to-end workflows are in references/typical_workflows.md. Per-topic detail lives in references/slide_management.md, references/tissue_masks.md, references/tile_extraction.md, references/filters_preprocessing.md, and references/visualization.md.

Read the full file on GitHub · 261 lines

Files

What ships with it

7 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 8d ago Changed · +17 lines af4b9a0ab9de
  2. 12d ago First seen · 244 lines · 65 tokens per session scan A bb488555cc3b

Subscribe to this mod's changes

histolab is a skill published in the GitHub repository K-Dense-AI/scientific-agent-skills (44,469 stars, last pushed today), licensed MIT. It adds 65 tokens to every session and 2,234 once invoked, about $0.0003 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

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