geniml

geniml is a skill for Claude Code, Codex from Lord1Egypt/scientific-agent-toolkit. It costs 89 tokens per session (2,357 once invoked), scanned A, a copy of geniml, MIT.

A Python package for machine learning with genomic interval data, such as BED files that describe regions of DNA. It can learn representations of regions and support similarity or clustering analysis.

In plain words
What is it for?
Use it to create region embeddings, analyze single-cell ATAC-seq data, build consensus peak sets, or combine genomic regions with metadata.
Why use it?
It turns genomic regions into data that machine-learning models can compare and analyze.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to create region embeddings, analyze single-cell ATAC-seq data, build consensus peak sets, or combine genomic regions with metadata.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/lord1egypt/scientific-agent-toolkit/geniml
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add Lord1Egypt/scientific-agent-toolkit --skill geniml
Clone the repo
git clone --depth 1 https://github.com/Lord1Egypt/scientific-agent-toolkit

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for geniml

README.md
[![agentmods](https://agentmods.dev/badge/skills/lord1egypt/scientific-agent-toolkit/geniml/github.svg)](https://agentmods.dev/skills/lord1egypt/scientific-agent-toolkit/geniml)
Your own site
<a href="https://agentmods.dev/skills/lord1egypt/scientific-agent-toolkit/geniml"><img src="https://agentmods.dev/badge/skills/lord1egypt/scientific-agent-toolkit/geniml/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for geniml

Your own site · 80×15
<a href="https://agentmods.dev/skills/lord1egypt/scientific-agent-toolkit/geniml"><img src="https://agentmods.dev/badge/skills/lord1egypt/scientific-agent-toolkit/geniml.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 89 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 2,357 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin 95% copy Near-identical to another mod in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00089 $0.02357
Opus 5 $0.00044 $0.01179
Sonnet 5 $0.00018 $0.00471
Haiku 4.5 $0.00009 $0.00236

Measured 10d ago against content hash b7ac15a83954, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-10, from the pricing page.

Security

Grade A, and why

geniml scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 10d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

Origin

This is a copy

95% identical to geniml — 9 lines differ, which has more behind it and is treated as the original. This page carries a canonical link to it rather than competing with it.

scientific-skills/geniml/SKILL.md · 317 lines

How it starts

The opening of the file, as written. The whole thing — 317 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Geniml: Genomic Interval Machine Learning

Overview

Geniml is a Python package for building machine learning models on genomic interval data from BED files. It provides unsupervised methods for learning embeddings of genomic regions, single cells, and metadata labels, enabling similarity searches, clustering, and downstream ML tasks.

Installation

Install geniml using uv:

uv pip install geniml

For ML dependencies (PyTorch, etc.):

uv pip install 'geniml[ml]'

Development version from GitHub:

uv pip install git+https://github.com/databio/geniml.git

Core Capabilities

Geniml provides five primary capabilities, each detailed in dedicated reference files:

1. Region2Vec: Genomic Region Embeddings

Train unsupervised embeddings of genomic regions using word2vec-style learning.

Use for: Dimensionality reduction of BED files, region similarity analysis, feature vectors for downstream ML.

Workflow:

  1. Tokenize BED files using a universe reference
  2. Train Region2Vec model on tokens
  3. Generate embeddings for regions

Reference: See references/region2vec.md for detailed workflow, parameters, and examples.

2. BEDspace: Joint Region and Metadata Embeddings

Train shared embeddings for region sets and metadata labels using StarSpace.

Use for: Metadata-aware searches, cross-modal queries (region→label or label→region), joint analysis of genomic content and experimental conditions.

Workflow:

  1. Preprocess regions and metadata
  2. Train BEDspace model
  3. Compute distances
  4. Query across regions and labels

Reference: See references/bedspace.md for detailed workflow, search types, and examples.

3. scEmbed: Single-Cell Chromatin Accessibility Embeddings

Train Region2Vec models on single-cell ATAC-seq data for cell-level embeddings.

Use for: scATAC-seq clustering, cell-type annotation, dimensionality reduction of single cells, integration with scanpy workflows.

Workflow:

  1. Prepare AnnData with peak coordinates
  2. Pre-tokenize cells
  3. Train scEmbed model
  4. Generate cell embeddings
  5. Cluster and visualize with scanpy

Read the full file on GitHub · 317 lines

Files

What ships with it

5 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 10d ago First seen · 317 lines · 89 tokens per session scan A b7ac15a83954

Subscribe to this mod's changes

geniml is a skill published in the GitHub repository Lord1Egypt/scientific-agent-toolkit (3 stars, last pushed 3mo ago), licensed MIT. It adds 89 tokens to every session and 2,357 once invoked, about $0.0004 per session on Opus 5. A static security scan graded it A with 0 findings. It is 95% identical to geniml, differing in 9 lines, and is treated as a copy.

Related

Other skills, from other repositories

cellxgene-census-query

Query CZ CELLxGENE Census (61M+ cells). Filter by cell type/tissue/disease, retrieve expression data, and integrate with scanpy/PyTorch for population-scale single-cell analysis. Use this skill when: (1) Querying single-cell expression data by cell type, tissue, or disease, (2) Exploring available single-cell datasets…

PharMolix/OpenBioMed · 105 tokens

alterlab-pyhealth

Develops, tests, and deploys clinical machine learning models with the PyHealth healthcare AI toolkit. Use when working with electronic health records (EHR), clinical prediction tasks (mortality, readmission, drug recommendation), medical coding systems (ICD, NDC, ATC), physiological signals (EEG, ECG), healthcare…

AlterLab-IEU/AlterLab-Academic-Skills · 117 tokens

alterlab-deepchem

Runs molecular machine learning with DeepChem — diverse featurizers, pre-built MoleculeNet benchmark datasets, and pre-trained models (ChemBERTa, GROVER) for property prediction (ADMET, toxicity, solubility) via traditional ML or graph neural networks. Use when running end-to-end molecular ML experiments that need…

AlterLab-IEU/AlterLab-Academic-Skills · 126 tokens

alterlab-hypogenic

Runs automated LLM-driven hypothesis generation and testing on tabular datasets with HypoGeniC, combining literature insights with data-driven testing. Use when systematically exploring hypotheses about patterns in empirical data (for example deception detection or content analysis). For manual hypothesis formulation…

AlterLab-IEU/AlterLab-Academic-Skills · 90 tokens

alterlab-esm

Run ESM protein language models — ESM3 for generative multimodal protein design across sequence, structure, and function, and ESM C for efficient embeddings and representations — locally or via the cloud Forge API. Use when working with protein sequences, structures, or function prediction, designing novel proteins…

AlterLab-IEU/AlterLab-Academic-Skills · 89 tokens

alterlab-molfeat

Featurizes molecules for machine learning with molfeat (100+ featurizers) — ECFP/MACCS/MAP4 fingerprints, RDKit and Mordred physicochemical descriptors, and pretrained embeddings (ChemBERTa, ChemGPT, GIN) exposed as scikit-learn transformers that convert SMILES into feature vectors. Use when turning molecules into…

AlterLab-IEU/AlterLab-Academic-Skills · 143 tokens