evo-protein-expression-analysis

evo-protein-expression-analysis is a skill for Claude Code, Codex from OpenLAIR/OpenSkill. It costs 69 tokens per session (1,121 once invoked), scanned A, original, Apache-2.0.

A Python utility for filling an Excel workbook with protein-expression values and statistics. It reads a raw data sheet, matches proteins and samples, computes group results in Python, and writes numeric values while preserving formatting.

In plain words
What is it for?
Use it with two-sheet proteomics workbooks to fill expression lookups, group statistics, and fold-change values for selected proteins and samples.
Why use it?
It avoids Excel formula-calculation issues: openpyxl can write formulas but cannot evaluate them, while this utility writes results that other programs can read directly.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it with two-sheet proteomics workbooks to fill expression lookups, group statistics, and fold-change values for selected proteins and samples.

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Install with agentmods
npx agentmods add skills/openlair/openskill/evo-protein-expression-analysis
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add OpenLAIR/OpenSkill --skill evo-protein-expression-analysis
Clone the repo
git clone --depth 1 https://github.com/OpenLAIR/OpenSkill

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for evo-protein-expression-analysis

README.md
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Your own site
<a href="https://agentmods.dev/skills/openlair/openskill/evo-protein-expression-analysis"><img src="https://agentmods.dev/badge/skills/openlair/openskill/evo-protein-expression-analysis/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

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Your own site · 80×15
<a href="https://agentmods.dev/skills/openlair/openskill/evo-protein-expression-analysis"><img src="https://agentmods.dev/badge/skills/openlair/openskill/evo-protein-expression-analysis.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 69 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,121 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00069 $0.01121
Opus 5 $0.00034 $0.00561
Sonnet 5 $0.00014 $0.00224
Haiku 4.5 $0.00007 $0.00112

Measured today against content hash b9cc36ff403e, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-11, from the pricing page.

Security

Grade A, and why

evo-protein-expression-analysis scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured today.

The scan reads SKILL.md. This mod also ships 1 executable file (scripts/utils.py), listed below but not scanned — reading those needs a real analyzer, not pattern matching.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

tasks-evolved/protein-expression-analysis/environment/skills/evo-protein-expression-analysis/SKILL.md · 105 lines

How it starts

The opening of the file, as written. The whole thing — 105 lines — stays where its author put it; the contents beside it link to each section on GitHub.

evo-protein-expression-analysis

Utilities for populating Excel workbooks with proteomics expression values, group statistics, and fold-change calculations while preserving all cell formatting.

CRITICAL: Write computed numeric values, NOT formulas

openpyxl does NOT have a calculation engine. If you write Excel formulas (strings starting with =), they will only be evaluated when the file is opened in Excel. Tools that read the file with data_only=True will see None for all formula cells.

You MUST compute values in Python and write float/int results directly.

Key facts about the protein_expression.xlsx task

  • File has two sheets: Task (where work happens) and Data (raw expression values).
  • Data sheet layout:
    • Column A = Protein_ID, Column B = Gene_Symbol, Column C = Description
    • Row 1 (D1:BA1) = 50 sample header names (e.g., "MDAMB468_BREAST_TenPx01")
    • Rows 2–201 = 200 proteins with log2-transformed expression values in D2:BA201
  • Task sheet layout:
    • Row 9 (C9:L9): "Control" or "Treated" group labels
    • Row 10 (C10:L10): 10 sample names (must match Data sheet headers exactly)
    • Column A, rows 11–20: 10 target Protein_IDs; Column B = Gene_Symbol
    • C11:L20 (yellow): expression values looked up from Data sheet
    • B24:K27 (yellow): per-protein group statistics
      • Row 24 = Control Mean, Row 25 = Control StdDev, Row 26 = Treated Mean, Row 27 = Treated StdDev
      • Column B → protein in row 11; Column K → protein in row 20
    • C32:D41 (yellow): fold change results
      • Column C = Log2 Fold Change (Treated Mean − Control Mean)
      • Column D = Fold Change (2^Log2FC)
      • Row 32 → protein in row 11; Row 41 → protein in row 20

Critical rules

  1. Write computed numeric values, not formulas — openpyxl doesn't evaluate formulas.
  2. Load with data_only=False to preserve existing formatting; only set .value on target cells.
  3. Data is already log2-transformed: use regular mean/stdev; Log2FC = Treated_Mean − Control_Mean; Fold Change = 2^Log2FC.
  4. Use Python's statistics.mean() and statistics.stdev() (sample stdev) for calculations.
  5. Group classification comes from text values in row 9 ("Control" / "Treated").
  6. Sample names in the Data sheet may have prefixes like "MDAMB468_BREAST_TenPx01" — match exactly against Task row 10.
  7. Do not alter file format, colors, fonts, or add macros/VBA.
  8. Setting cell.value preserves existing cell formatting (fill, font, border).

Read the full file on GitHub · 105 lines

Files

What ships with it

1 file beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. today First seen · 105 lines · 69 tokens per session scan A b9cc36ff403e

Subscribe to this mod's changes

evo-protein-expression-analysis is a skill published in the GitHub repository OpenLAIR/OpenSkill (88 stars, last pushed yesterday), licensed Apache-2.0. It adds 69 tokens to every session and 1,121 once invoked, about $0.0003 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-11.

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