Open-source, local-first desktop AI research workbench for scientific computing with Python/R, MCP bioinformatics tools, SSH/WSL/GPU runtimes, and OpenAI/Anthropic models.
xuzhougeng/wisp-science is a local-first desktop workbench for scientific research that combines AI assistants with Python and R computing, literature search, scientific databases, and remote runtimes. Researchers use it to run analyses, manage project artifacts, and preserve evidence and decisions on their own machines. Its catalogue skills and instruction extend the workbench’s reusable agent workflows.
This repository also configures its own agents. See what wisp-science tells them →
Skill Claude CodeCodex
Use the InfiniSynapse CLI (agentinfini) for multi-turn AI data-analysis tasks, database/RAG context, and task workspace files. Use when the user mentions InfiniSynapse, agentinfini, database or RAG analysis, or asks to delegate analysis through InfiniSynapse.
Skill Claude CodeCodex
Organize multi-step scientific analyses into reproducible, self-contained modules. Use for workflows such as QC→PCA→DEG→GSEA that produce scripts, inputs, figures, tables, and methods. Creates a stable module layout, records exact inputs/parameters/package and database versions in each module README, keeps large data…
Skill Claude CodeCodex
A reviewer for life-science and biomedical papers, PDFs, figures, captions, and screenshots. It examines the scientific question, experiments, evidence, causality, and limitations.
Skill Claude CodeCodex
A literature search that finds real academic papers challenging a claim through opposing findings, limits, alternative explanations, methodological criticism, or failed replications.
Skill Claude CodeCodex
A research skill that builds a knowledge map around a concept using real paper abstracts. It also creates a Mermaid diagram, a standalone HTML map, and beginner reading suggestions.
Skill Claude Code
A research-onboarding review that maps the main concepts in a field and explains how the field developed over time.
Skill Claude Code
A research-planning review that checks whether an idea overlaps with existing work, finds literature that supports it, and identifies likely challenges before the project starts.
Skill Claude Code
An evidence-review procedure that searches for research supporting and opposing a stated viewpoint, then compares the two sides.
Skill Claude CodeCodex
A literature search that compares a research idea with existing papers from several angles and highlights the closest matches.
Skill Claude CodeCodex
A literature-search tool for finding real academic papers that support a claim. It also explains how each paper supports the claim and reports when no suitable source is found.
Skill Claude CodeCodex
A research-history review that traces a topic or seed paper back to its earlier sources and forward to newer developments.
Skill Claude CodeCodex
Use this skill to drive Wisp Browser Runtime sessions (shared daily Chrome or workspace Chrome) — open pages, read them, click, fill and submit forms, navigate, switch tabs, or scrape content that needs the user's existing cookies and login state. Triggers when the user asks to do something in their browser, log into…
Skill Claude CodeCodex
Set up and validate a reproducible Python or R environment on a Wisp execution context. Use for a selected local, WSL, or direct SSH context when installing scientific packages, configuring caches, recording interpreter activation, or producing an environment smoke test. Do not use for scheduler clusters or managed…
Skill Claude CodeCodex
Author a Wisp custom theme CSS file that uses documented tokens and import constraints. Use when the user wants a custom look, hide the paragraph lead bar, restyle chat Markdown, override colors, or import a stylesheet under Settings → Appearance.
Skill Claude CodeCodex
Create a Wisp specialist or author a project-local skill using the tools Wisp actually exposes. Use when the user wants a custom Agent persona, a restricted specialist loadout, a new skill, or changes to an existing project-local skill.
Skill Codex
A workflow for turning books about concepts, theories, or analysis methods into reusable task instructions. It scans document images, links claims to evidence, and checks the result through human review.
Skill Claude CodeCodex
Compose or improve a publication-grade multi-panel scientific figure from a claim, concrete data paths, or an existing image. Use for figure outlining, parallel panel rendering, exact-grid composition, visual inspection, and adversarial figure review. Use figure-style for one standalone plot and paper-narrative for…
Skill Claude CodeCodex
A review of scientific figure images for duplicated, reused, altered, or uninformative panels. Scientific figures are the charts, photographs, and image panels included in research papers.
Skill Claude CodeCodex
Correctness and legibility checklist for publication figures, plus a matplotlib sidecar. Load before plotting anything and call applyfigurestyle() (role-mapped font ladder, outward ticks, frameless legends, 300-dpi saves, CJK-safe fonts). Covers data fidelity, label budgets, axis/colour/type rules, chart choice by…
Skill Claude CodeCodex
Build a sourced research dossier for one therapeutic indication — patient population, epidemiology, disease biology, standard of care, regulatory path, and landmark trials. Use when the user asks for an indication overview, disease landscape, or trial-design background.
Skill Claude CodeCodex
Instructions for turning a scientific paper PDF into a journal-club presentation or literature report. They require reconstructing the paper's scientific logic before creating the slides.
Skill Claude CodeCodex
Retrieve, verify, and synthesize scientific literature. Use for seminal-paper lookups, evidence summaries, method comparisons, and gap analyses. Every citation must come from a live lookup, never from memory; retractions are checked; the deliverable is argued prose with resolvable DOI links.
Skill Claude CodeCodex
A skill for setting up the local runtime for wisp-science projects, including Python, Node.js, and bioinformatics environments.
Skill Claude CodeCodex
Judge and reshape the story told by a manuscript and its figure deck. Use when revising paper structure, testing whether Figure 1 is a hook, ordering figures, moving panels, identifying missing analyses, or defining the claim passed to figure-composer.
At most 3 mods per repository are shown here, and a mod shipped inside a plugin is left to that plugin's page — the rest are on their repository pages: