cell-annotation

cell-annotation is a skill for Claude Code, Codex from zongtingwei/Bioclaw_Skills_Hub. It costs 33 tokens per session (1,087 once invoked), scanned A, original, MIT.

A workflow for assigning biological cell-type labels to single-cell RNA sequencing data, which measures gene activity in individual cells. It combines known gene markers, reference datasets, and automated predictions while recording uncertainty.

In plain words
What is it for?
Use it to label clusters or individual cells, review marker genes, transfer labels from a reference atlas, and export both predicted and curated labels.
Why use it?
It reduces the need to label clusters by hand and helps avoid overly specific labels when the evidence is weak or reference data do not match.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to label clusters or individual cells, review marker genes, transfer labels from a reference atlas, and export both predicted and curated labels.

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Install with agentmods
npx agentmods add skills/zongtingwei/bioclaw_skills_hub/cell-annotation
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add zongtingwei/Bioclaw_Skills_Hub --skill cell-annotation
Clone the repo
git clone --depth 1 https://github.com/zongtingwei/Bioclaw_Skills_Hub

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for cell-annotation

README.md
[![agentmods](https://agentmods.dev/badge/skills/zongtingwei/bioclaw_skills_hub/cell-annotation/github.svg)](https://agentmods.dev/skills/zongtingwei/bioclaw_skills_hub/cell-annotation)
Your own site
<a href="https://agentmods.dev/skills/zongtingwei/bioclaw_skills_hub/cell-annotation"><img src="https://agentmods.dev/badge/skills/zongtingwei/bioclaw_skills_hub/cell-annotation/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for cell-annotation

Your own site · 80×15
<a href="https://agentmods.dev/skills/zongtingwei/bioclaw_skills_hub/cell-annotation"><img src="https://agentmods.dev/badge/skills/zongtingwei/bioclaw_skills_hub/cell-annotation.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 33 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,087 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00033 $0.01087
Opus 5 $0.00016 $0.00544
Sonnet 5 $0.00007 $0.00217
Haiku 4.5 $0.00003 $0.00109

Measured 12d ago against content hash 72ed42034a74, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-12, from the pricing page.

Security

Grade A, and why

cell-annotation scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 12d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/single-cell-and-spatial/cell-annotation/SKILL.md · 155 lines

How it starts

The opening of the file, as written. The whole thing — 155 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Cell Annotation

Version Compatibility

Reference examples assume:

  • scanpy 1.10+
  • celltypist 1.6+
  • pandas 2.2+

Before using code patterns, verify installed versions match the environment:

  • Python: python -c "import scanpy, celltypist; print(scanpy.__version__, celltypist.__version__)"
  • If APIs differ, inspect the installed docs and adapt the pattern instead of retrying unchanged.

Overview

Use this skill when the user wants cluster labels or per-cell labels for scRNA-seq. The default stance is:

  1. inspect markers first
  2. run reference-based annotation
  3. keep uncertainty explicit
  4. export both raw predicted labels and a curated final label column

When To Use This Skill

  • clusters already exist and need biological labels
  • the dataset has a relevant reference atlas or known marker panels
  • the user wants CellTypist or similar automated annotation

Quick Route

  • If clusters are unstable or clearly QC-driven, fix preprocessing before annotation.
  • If the atlas mismatch is severe, prefer broad lineage labels over overconfident fine labels.
  • If multiple methods disagree, mark labels as uncertain instead of forcing a consensus.

Progressive Disclosure

Default Rules

  • Never accept automated labels without checking marker expression.
  • Keep per-cell predictions and cluster-level curated labels separate.
  • Use Unknown, Uncertain, or Ambiguous when evidence is weak.
  • Document the reference model or atlas used.

Expected Inputs

  • processed h5ad with clusters and embeddings
  • marker gene lists or known lineage markers
  • optional reference atlas or model

Expected Outputs

  • results/annotated.h5ad
  • results/cell_labels.tsv
  • results/cluster_annotation_summary.tsv
  • figures/umap_cell_types.pdf
  • figures/marker_dotplot.pdf

Read the full file on GitHub · 155 lines

Files

What ships with it

3 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 12d ago First seen · 155 lines · 33 tokens per session scan A 72ed42034a74

Subscribe to this mod's changes

cell-annotation is a skill published in the GitHub repository zongtingwei/Bioclaw_Skills_Hub (26 stars, last pushed 5mo ago), licensed MIT. It adds 33 tokens to every session and 1,087 once invoked, about $0.0002 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

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