long-read-genomics

long-read-genomics is a skill for Claude Code, Codex from zongtingwei/Bioclaw_Skills_Hub. It costs 30 tokens per session (874 once invoked), scanned A, original, MIT.

A workflow for analysing long-read sequencing data from Nanopore or PacBio machines. Long reads are DNA or RNA sequences that cover much larger stretches than typical short-read data.

In plain words
What is it for?
It supports quality checks, alignment, sequence polishing, methylation-aware analysis, phasing, and discovery of structural variants.
Why use it?
It provides steps suited to long-read-specific errors and measurements, which differ from ordinary short-read sequencing workflows.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit It supports quality checks, alignment, sequence polishing, methylation-aware analysis, phasing, and discovery of structural variants.

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Install with agentmods
npx agentmods add skills/zongtingwei/bioclaw_skills_hub/long-read-genomics
Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add zongtingwei/Bioclaw_Skills_Hub --skill long-read-genomics
Clone the repo
git clone --depth 1 https://github.com/zongtingwei/Bioclaw_Skills_Hub

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for long-read-genomics

README.md
[![agentmods](https://agentmods.dev/badge/skills/zongtingwei/bioclaw_skills_hub/long-read-genomics/github.svg)](https://agentmods.dev/skills/zongtingwei/bioclaw_skills_hub/long-read-genomics)
Your own site
<a href="https://agentmods.dev/skills/zongtingwei/bioclaw_skills_hub/long-read-genomics"><img src="https://agentmods.dev/badge/skills/zongtingwei/bioclaw_skills_hub/long-read-genomics/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for long-read-genomics

Your own site · 80×15
<a href="https://agentmods.dev/skills/zongtingwei/bioclaw_skills_hub/long-read-genomics"><img src="https://agentmods.dev/badge/skills/zongtingwei/bioclaw_skills_hub/long-read-genomics.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 30 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 874 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe.
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00030 $0.00874
Opus 5 $0.00015 $0.00437
Sonnet 5 $0.00006 $0.00175
Haiku 4.5 $0.00003 $0.00087

Measured 13d ago against content hash 61db16ce6195, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-12, from the pricing page.

Security

Grade A, and why

long-read-genomics scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 13d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

skills/genomics-and-variation/long-read-genomics/SKILL.md · 137 lines

How it starts

The opening of the file, as written. The whole thing — 137 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Long-Read Genomics

Version Compatibility

Reference examples assume recent stable releases of the preferred tools, especially long-read and the other tools listed below.

Before using code or command patterns, verify installed versions match the environment:

  • Python: python -c "import <module>; print(<module>.__version__)"
  • CLI: <tool> --version
  • If signatures differ, inspect the installed help or API and adapt the pattern instead of retrying unchanged.

Overview

Workflow for nanopore or PacBio long-read QC, alignment, polishing, methylation-aware analysis, and structural variant discovery.

When To Use This Skill

  • use when the dataset is nanopore or PacBio long-read sequencing
  • use when structural variants, phasing, polishing, or long-read methylation are part of the task
  • use when long-read-specific QC and alignment assumptions must be respected

Quick Route

  • If the input is raw or minimally processed data, start with validation and QC before any modeling.
  • If the input is already processed, skip directly to the first workflow step that matches the user goal.
  • If the user asks for a biological conclusion, always produce at least one QC or confidence artifact alongside the final result.

Progressive Disclosure

  • Read references/technical_reference.md when you need deeper tool-selection rules, environment adaptation notes, or extra validation guidance.
  • Keep SKILL.md as the main execution path and load the reference file only when the task or failure mode needs the extra detail.

Default Rules

  • Prefer Python-first workflows unless the task explicitly requires something else.
  • Keep intermediate and final outputs separated.
  • Record software versions, reference builds, and key parameters when they affect interpretation.
  • Favor reproducible tables and figures over one-off interactive-only outputs.

Expected Inputs

  • long-read FASTQ or raw data
  • reference genome
  • sample metadata

Expected Outputs

  • aligned long-read files
  • polished consensus or assembly updates
  • long-read variant summaries

Read the full file on GitHub · 137 lines

Files

What ships with it

2 files beside SKILL.md in the same directory: the scripts, references and assets a skill reads on demand. Not counted in the per-session cost; read them before you install if any of them is executable.

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 13d ago First seen · 137 lines · 30 tokens per session scan A 61db16ce6195

Subscribe to this mod's changes

long-read-genomics is a skill published in the GitHub repository zongtingwei/Bioclaw_Skills_Hub (26 stars, last pushed 5mo ago), licensed MIT. It adds 30 tokens to every session and 874 once invoked, about $0.0002 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

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