metabolic-study-planner

metabolic-study-planner is a skill for Claude Code, Codex from aiming-lab/AutoResearchClaw. It costs 69 tokens per session (1,706 once invoked), scanned A, original, MIT.

A study-planning assistant for constraint-based metabolic modelling, a way to study metabolism by calculating reaction rates under biological constraints. It turns a broad biological topic into a concrete study plan with an organism, model, conditions, perturbation, measurements, figures, and risks.

In plain words
What is it for?
Use it to plan studies involving growth, product secretion, gene knockouts, nutrient changes, oxygen sweeps, essential genes, or yield optimisation.
Why use it?
It fills in the scientific and practical choices needed before modelling can produce a focused, executable study.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to plan studies involving growth, product secretion, gene knockouts, nutrient changes, oxygen sweeps, essential genes, or yield optimisation.

Compare 6 skills from other repositories ↓
Install with agentmods
npx agentmods add skills/aiming-lab/autoresearchclaw/metabolic-study-planner
About the project

AutoResearchClaw is a system that turns a research idea into a scientific paper through autonomous and collaborative AI research workflows. It is for researchers who want agents to investigate questions, run experiments, and produce papers, with optional human guidance. Catalogue skills and agents provide parts of its research workflow.

aiming-lab/AutoResearchClaw · 14,375 stars · on GitHub

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add aiming-lab/AutoResearchClaw --skill metabolic-study-planner
Clone the repo
git clone --depth 1 https://github.com/aiming-lab/AutoResearchClaw

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for metabolic-study-planner

README.md
[![agentmods](https://agentmods.dev/badge/skills/aiming-lab/autoresearchclaw/metabolic-study-planner/github.svg)](https://agentmods.dev/skills/aiming-lab/autoresearchclaw/metabolic-study-planner)
Your own site
<a href="https://agentmods.dev/skills/aiming-lab/autoresearchclaw/metabolic-study-planner"><img src="https://agentmods.dev/badge/skills/aiming-lab/autoresearchclaw/metabolic-study-planner/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for metabolic-study-planner

Your own site · 80×15
<a href="https://agentmods.dev/skills/aiming-lab/autoresearchclaw/metabolic-study-planner"><img src="https://agentmods.dev/badge/skills/aiming-lab/autoresearchclaw/metabolic-study-planner.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 69 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 1,706 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00069 $0.01706
Opus 5 $0.00034 $0.00853
Sonnet 5 $0.00014 $0.00341
Haiku 4.5 $0.00007 $0.00171

Measured 10d ago against content hash c61bc06caa2f, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-09, from the pricing page.

Security

Grade A, and why

metabolic-study-planner scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 10d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

external/agents/Biology-Agent/skills/metabolic-study-planner/SKILL.md · 242 lines

How it starts

The opening of the file, as written. The whole thing — 242 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Metabolic Study Planner

Overview

Use this skill before gsmm-builder, fba-simulator, and flux-analyzer when the project starts from a broad prompt such as "do a metabolic flux analysis paper" or "find a publishable idea in microbial metabolism".

The goal is to turn a vague topic into a concrete, executable, paper-shaped study plan:

organism + model + condition + perturbation + metric + figure set + claim

This is the MFA analogue of choosing a collider process and parameter scan before generating events.

Planning Inputs

Extract or infer the following:

Field Examples
Biological scope microbial metabolism, cancer metabolism, yeast fermentation, tuberculosis
Organism E. coli, S. cerevisiae, human Recon3D, M. tuberculosis
Model source BiGG ID, local SBML/JSON, manually constructed toy model
Objective biomass, product secretion, ATP maintenance, dual objective
Condition aerobic, anaerobic, carbon source, nutrient limitation
Perturbation gene knockout, reaction knockout, medium swap, oxygen sweep
Target output growth, product yield, essential genes, secretion profile
Paper type mechanism hypothesis, metabolic engineering strategy, benchmark, reproduction

If the user provides no organism, start with one of these low-risk defaults:

Default Model Why
E. coli K-12 iJO1366 or core model Fast, well curated, standard for FBA papers
S. cerevisiae iMM904 Fermentation and product-yield studies
Human metabolism Recon3D Disease metabolism, but larger and harder
M. tuberculosis iNJ661 Essentiality and drug-target hypotheses

Prefer E. coli for fully autonomous first runs because it is fast and interpretable.

Study Archetypes

Archetype A: Knockout Strategy for Product Overproduction

Use when the topic mentions metabolic engineering, bio-production, yield, or fermentation.

Plan:

  1. Select a product exchange reaction, e.g. succinate, lactate, ethanol, acetate.
  2. Run WT FBA and pFBA under a defined medium.
  3. Screen single reaction/gene knockouts.
  4. Rank perturbations by product secretion subject to retaining growth.
  5. Validate top candidates with FVA and carbon-source sensitivity.

Read the full file on GitHub · 242 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 10d ago First seen · 242 lines · 69 tokens per session scan A c61bc06caa2f

Subscribe to this mod's changes

metabolic-study-planner is a skill published in the GitHub repository aiming-lab/AutoResearchClaw (14,375 stars, last pushed 21d ago), licensed MIT. It adds 69 tokens to every session and 1,706 once invoked, about $0.0003 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

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