mfa-pipeline-orchestrator

mfa-pipeline-orchestrator is a skill for Claude Code, Codex from aiming-lab/AutoResearchClaw. It costs 56 tokens per session (962 once invoked), scanned A, original, MIT.

An orchestrator for a full metabolic flux analysis pipeline, from loading and checking a metabolic model to running flux calculations, analysing phenotypes, and producing publication figures. Metabolic flux analysis estimates how material flows through an organism’s reactions.

In plain words
What is it for?
Use it when you have an organism, BiGG model, or reaction list and want end-to-end analyses such as gene essentiality, phase planes, yield optimisation, or wild-type versus mutant comparisons.
Why use it?
It coordinates the separate modelling steps and keeps progress files so a pipeline can be resumed after an interrupted or failed step.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one. Also seen: mentions subagents.

Good fit Use it when you have an organism, BiGG model, or reaction list and want end-to-end analyses such as gene essentiality, phase planes, yield optimisation, or wild-type versus mutant comparisons.

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Install with agentmods
npx agentmods add skills/aiming-lab/autoresearchclaw/mfa-pipeline-orchestrator
About the project

AutoResearchClaw is a system that turns a research idea into a scientific paper through autonomous and collaborative AI research workflows. It is for researchers who want agents to investigate questions, run experiments, and produce papers, with optional human guidance. Catalogue skills and agents provide parts of its research workflow.

aiming-lab/AutoResearchClaw · 14,389 stars · on GitHub

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add aiming-lab/AutoResearchClaw --skill mfa-pipeline-orchestrator
Clone the repo
git clone --depth 1 https://github.com/aiming-lab/AutoResearchClaw

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for mfa-pipeline-orchestrator

README.md
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Your own site
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Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for mfa-pipeline-orchestrator

Your own site · 80×15
<a href="https://agentmods.dev/skills/aiming-lab/autoresearchclaw/mfa-pipeline-orchestrator"><img src="https://agentmods.dev/badge/skills/aiming-lab/autoresearchclaw/mfa-pipeline-orchestrator.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 56 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 962 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00056 $0.00962
Opus 5 $0.00028 $0.00481
Sonnet 5 $0.00011 $0.00192
Haiku 4.5 $0.00006 $0.00096

Measured 12d ago against content hash b244b759f6db, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-11, from the pricing page.

Security

Grade A, and why

mfa-pipeline-orchestrator scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 12d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

external/agents/Biology-Agent/skills/mfa-pipeline-orchestrator/SKILL.md · 101 lines

How it starts

The opening of the file, as written. The whole thing — 101 lines — stays where its author put it; the contents beside it link to each section on GitHub.

MFA Pipeline Orchestrator

Overview

Coordinates all mfa-agent sub-agents in sequence, tracking progress via progress/ markdown files so any failed step can be resumed independently.

Full pipeline:

Model source (BIGG ID / custom reactions)
  → [model-builder]     models/<Model>.json  +  validation report
  → [fba-runner]        simulations/fba_fluxes.csv  +  scan_summary.json
  → [flux-analyzer]     analysis/essentiality.csv  +  phase_plane.png
  → [metabolic-pheno-analyzer]  output/figures/*.pdf  +  yield table

Workflow

Step 0: Parse User Request

Extract and record in progress/step0_inputs.md:

  • Model source (BIGG ID or custom)
  • Organism and condition (aerobic/anaerobic, carbon source, concentration)
  • Objective reaction (biomass or product)
  • Gene knockouts to apply
  • Analysis goals (essentiality, phase plane, yield optimisation, WT vs. mutant comparison)
  • Target product (if yield analysis requested)

Step 1: Invoke model-builder

Provide: model source, medium constraints, objective, knockouts. Wait for progress/step1_metabolic_model.md. Read: model file path, WT growth rate, model statistics.

Step 2: Invoke fba-runner

Provide: model path, simulation types requested (FBA, pFBA, FVA, knockout screen), carbon source sweep if requested. Wait for progress/step2_fba_simulation.md. Read: flux CSV paths, essential gene count, secretion fluxes.

Step 3: Invoke flux-analyzer

Provide: model path, FBA results, analysis goals (essentiality, phase plane, sampling), nutrient pair for phase plane. Wait for progress/step3_flux_analysis.md. Read: essential genes, phase plane optimum, engineering targets.

Step 4: Invoke metabolic-pheno-analyzer

Provide: model path, all previous results, target product, publication requirements. Wait for progress/step4_metabolic_phenotype.md. Read: max theoretical yield, figure paths.

Progress File Specification

progress/step1_metabolic_model.md

# Step 1: Metabolic Model
## Status: PASS / FAIL
## Model: <BIGG_ID>.json
## Reactions: N  Metabolites: M  Genes: G
## WT growth rate: X h⁻¹
## Validation: mass balance errors=0, dead-ends=N

Read the full file on GitHub · 101 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 12d ago First seen · 101 lines · 56 tokens per session scan A b244b759f6db

Subscribe to this mod's changes

mfa-pipeline-orchestrator is a skill published in the GitHub repository aiming-lab/AutoResearchClaw (14,389 stars, last pushed 23d ago), licensed MIT. It adds 56 tokens to every session and 962 once invoked, about $0.0003 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

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