basic-discovery-translational-opportunity-finder

basic-discovery-translational-opportunity-finder is a skill for Claude Code, Codex from aipoch/medical-research-skills. It costs 106 tokens per session (3,094 once invoked), scanned A, original, MIT.

An evidence-aware framework for connecting a basic-research discovery to possible clinical or therapeutic uses. It helps translate findings about mechanisms, pathways, or cells into questions about diagnosis, prognosis, treatment response, monitoring, or drug development.

In plain words
What is it for?
Use it to map plausible translational opportunities, review the evidence behind each one, identify gaps, and choose a credible next research direction.
Why use it?
Basic findings often need several missing links before they can support a medical application. This framework compares possible paths and shows which are supported, premature, crowded, or weakly justified.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it to map plausible translational opportunities, review the evidence behind each one, identify gaps, and choose a credible next research direction.

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Install with agentmods
npx agentmods add skills/aipoch/medical-research-skills/basic-discovery-translational-opportunity-finder
About the project

Medical Research Agent Skills is a library of agent instructions for medical and biomedical research, covering evidence analysis, study protocol design, data analysis, and academic writing. Researchers use it to guide compatible coding agents through common scientific workflows. The catalogue contains many of the library's skills and commands.

aipoch/medical-research-skills · 1,860 stars · on GitHub · aipoch.com

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add aipoch/medical-research-skills --skill basic-discovery-translational-opportunity-finder
Clone the repo
git clone --depth 1 https://github.com/aipoch/medical-research-skills

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for basic-discovery-translational-opportunity-finder

README.md
[![agentmods](https://agentmods.dev/badge/skills/aipoch/medical-research-skills/basic-discovery-translational-opportunity-finder/github.svg)](https://agentmods.dev/skills/aipoch/medical-research-skills/basic-discovery-translational-opportunity-finder)
Your own site
<a href="https://agentmods.dev/skills/aipoch/medical-research-skills/basic-discovery-translational-opportunity-finder"><img src="https://agentmods.dev/badge/skills/aipoch/medical-research-skills/basic-discovery-translational-opportunity-finder/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for basic-discovery-translational-opportunity-finder

Your own site · 80×15
<a href="https://agentmods.dev/skills/aipoch/medical-research-skills/basic-discovery-translational-opportunity-finder"><img src="https://agentmods.dev/badge/skills/aipoch/medical-research-skills/basic-discovery-translational-opportunity-finder.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 106 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 3,094 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00106 $0.03094
Opus 5 $0.00053 $0.01547
Sonnet 5 $0.00021 $0.00619
Haiku 4.5 $0.00011 $0.00309

Measured 9d ago against content hash b3d5162877d5, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-12, from the pricing page.

Security

Grade A, and why

basic-discovery-translational-opportunity-finder scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 9d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

awesome-med-research-skills/Evidence Insight/basic-discovery-translational-opportunity-finder/SKILL.md · 347 lines

How it starts

The opening of the file, as written. The whole thing — 347 lines — stays where its author put it; the contents beside it link to each section on GitHub.

Source: https://github.com/aipoch/medical-research-skills

Basic Discovery Translational Opportunity Finder

You are an expert translational-opportunity analyst for biomedical research.

Task: Generate a structured, evidence-aware translational opportunity map that links a basic-research finding to plausible clinical or therapeutic use cases.

This skill is for users who want to understand:

  • how a mechanism finding could connect to real translational value,
  • which clinical use cases are actually plausible,
  • what evidence already supports or weakens each path,
  • where the translational chain is missing critical links,
  • and which opportunity paths are strong, premature, crowded, or weakly justified.

This is not a generic brainstorming tool and not a clinical recommendation tool. The goal is to convert a basic finding into a usable translational decision map.


Reference Module Integration

The references/ directory defines the operational standard for this skill and must be actively used during execution.

Use the reference modules as follows:

  • references/discovery-unit-framework.md → use when defining the basic-research signal or discovery unit in Sections A and C.
  • references/translational-use-case-framework.md → use when assigning translational directions in Sections C–F.
  • references/bridge-evidence-framework.md → use when judging whether a mechanism finding has enough bridge evidence to support a translational path in Sections C–E.
  • references/clinical-interface-rules.md → use when deciding whether the opportunity is diagnostic, stratification, prognostic, treatment-response, monitoring, or therapeutic-development facing in Sections C–F.
  • references/feasibility-and-burden-audit.md → use when auditing assay burden, validation burden, implementation burden, and development friction in Sections D–G.
  • references/translation-barrier-rules.md → use when identifying failure points, overclaim risk, missing evidence links, and false translation signals in Sections E–G.
  • references/output-section-guidance.md → use as the section-level formatting and content control standard for Sections A–I.

Read the full file on GitHub · 347 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 9d ago First seen · 347 lines · 106 tokens per session scan A b3d5162877d5

Subscribe to this mod's changes

basic-discovery-translational-opportunity-finder is a skill published in the GitHub repository aipoch/medical-research-skills (1,860 stars, last pushed 1mo ago), licensed MIT. It adds 106 tokens to every session and 3,094 once invoked, about $0.0005 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-09-03.

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