gsva-analysis-and-visualization

gsva-analysis-and-visualization is a skill for Claude Code, Codex from aipoch/medical-research-skills. It costs 88 tokens per session (4,065 once invoked), scanned A, original, MIT.

A workflow that gives each sample a score for the activity of groups of genes, called pathways, using GSVA or ssGSEA. It can compare those pathway scores between sample groups and create a heatmap.

In plain words
What is it for?
Use it with a bulk gene-expression matrix and sample group file for pathway comparisons, including KEGG or MSigDB analyses, or to make a heatmap from saved results.
Why use it?
It summarizes gene-level measurements into pathway-level results, making it easier to see which biological processes differ between groups.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Good fit Use it with a bulk gene-expression matrix and sample group file for pathway comparisons, including KEGG or MSigDB analyses, or to make a heatmap from saved results.

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Install with agentmods
npx agentmods add skills/aipoch/medical-research-skills/gsva-analysis-and-visualization
About the project

Medical Research Agent Skills is a library of agent instructions for medical and biomedical research, covering evidence analysis, study protocol design, data analysis, and academic writing. Researchers use it to guide compatible coding agents through common scientific workflows. The catalogue contains many of the library's skills and commands.

aipoch/medical-research-skills · 1,860 stars · on GitHub · aipoch.com

Install

Getting it into your agent

One page per mod, every tool's command on it. A separate URL per tool would split the same page into five that compete with each other.

Any agent
npx skills add aipoch/medical-research-skills --skill gsva-analysis-and-visualization
Clone the repo
git clone --depth 1 https://github.com/aipoch/medical-research-skills

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for gsva-analysis-and-visualization

README.md
[![agentmods](https://agentmods.dev/badge/skills/aipoch/medical-research-skills/gsva-analysis-and-visualization/github.svg)](https://agentmods.dev/skills/aipoch/medical-research-skills/gsva-analysis-and-visualization)
Your own site
<a href="https://agentmods.dev/skills/aipoch/medical-research-skills/gsva-analysis-and-visualization"><img src="https://agentmods.dev/badge/skills/aipoch/medical-research-skills/gsva-analysis-and-visualization/github.svg" alt="Measured on agentmods" height="20"></a>

Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

agentmods 80×15 button for gsva-analysis-and-visualization

Your own site · 80×15
<a href="https://agentmods.dev/skills/aipoch/medical-research-skills/gsva-analysis-and-visualization"><img src="https://agentmods.dev/badge/skills/aipoch/medical-research-skills/gsva-analysis-and-visualization.svg" alt="Reviewed on agentmods" width="80" height="20"></a>
Per session 88 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 4,065 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00088 $0.04065
Opus 5 $0.00044 $0.02032
Sonnet 5 $0.00018 $0.00813
Haiku 4.5 $0.00009 $0.00407

Measured 12d ago against content hash 5fc350c43e98, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-11, from the pricing page.

Security

Grade A, and why

gsva-analysis-and-visualization scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 12d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

awesome-med-research-skills/Data Analysis/gsva-analysis-and-visualization/SKILL.md · 343 lines

How it starts

The opening of the file, as written. The whole thing — 343 lines — stays where its author put it; the contents beside it link to each section on GitHub.

GSVA Analysis And Visualization

When to Use

Use this skill when the user wants one of the following:

  • Pathway-level GSVA or ssGSEA analysis from a bulk expression matrix plus a sample group file
  • Case-vs-control or treatment-vs-control pathway enrichment comparison using GSVA plus limma
  • KEGG or MSigDB pathway analysis for bulk RNA-seq or microarray-like expression data
  • Heatmap generation from an existing data/GSVA_list.rda result object
  • A reproducible CLI-backed GSVA workflow with saved tables, an .rda object, and a PDF heatmap

Typical request patterns:

  • "Run GSVA on my bulk RNA-seq matrix and compare case vs control"
  • "Use ssGSEA to score pathways and save the pathway differential results"
  • "Generate a KEGG pathway heatmap from my saved GSVA result"
  • "Do pathway enrichment with GSVA for these grouped bulk samples"

Execution Model

This is a hybrid skill.

  1. Use SKILL.md to verify that the request is in scope.
  2. Use scripts/main.R for real execution.
  3. Use --mode analyze to compute pathway scores and differential results.
  4. Use --mode visualize to reuse an existing data/GSVA_list.rda and generate a heatmap. In visualize mode, GSVA_list.rda must exist in output_dir/data/; run analyze or full mode first if it is missing (SKILL_FILE_NOT_FOUND will be raised otherwise).
  5. Use --mode full to run analysis and visualization in one pass.
  6. Read reference files only when you need algorithm details, troubleshooting, or additional CLI examples.

When to Read External Files

Situation File to Read Purpose
Need algorithm details references/algorithm.md Understand GSVA, limma, and heatmap generation logic
Need to run analysis or plotting scripts/main.R Execute the CLI entry point
Encounter errors references/troubleshooting.md Find standard error codes and fixes
Need more CLI examples or the baseline execution record references/cli-guide.md Copy ready-to-run commands and review the recorded test run
Need sample input files tests/data/ Use the bundled demo matrix and group file

Read the full file on GitHub · 343 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 12d ago First seen · 343 lines · 88 tokens per session scan A 5fc350c43e98

Subscribe to this mod's changes

gsva-analysis-and-visualization is a skill published in the GitHub repository aipoch/medical-research-skills (1,860 stars, last pushed 1mo ago), licensed MIT. It adds 88 tokens to every session and 4,065 once invoked, about $0.0004 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

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