lasso-logistics-analysis

lasso-logistics-analysis is a skill for Claude Code, Codex from aipoch/medical-research-skills. It costs 55 tokens per session (2,268 once invoked), scanned A, original, MIT.

A workflow for selecting features with LASSO logistic regression from an expression or other biological feature matrix. Logistic regression predicts one of two groups, while LASSO can reduce the selected feature set.

In plain words
What is it for?
Use it with expression matrices and group labels to compare two classes, select features, and save analysis results. It is not intended for multiclass classification, survival models or ordinary linear regression.
Why use it?
It provides cross-validation and coefficient-path visualization for building and interpreting a binary classification model from omics data.

Skill for Claude CodeCodex

Written for no agent in particular: nothing here depends on one.

Needs its repository: it runs a file that does not travel with it, so clone the repository first. The line is --output_dir ./output/ \.

Good fit Use it with expression matrices and group labels to compare two classes, select features, and save analysis results. It is not intended for multiclass classification, survival models or ordinary linear regression.

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About the project

Medical Research Agent Skills is a library of agent instructions for medical and biomedical research, covering evidence analysis, study protocol design, data analysis, and academic writing. Researchers use it to guide compatible coding agents through common scientific workflows. The catalogue contains many of the library's skills and commands.

aipoch/medical-research-skills · 1,860 stars · on GitHub · aipoch.com

Install

Getting it into your agent

It runs from inside its repository, so the clone comes first — what it calls does not travel with the file alone.

Clone the repo
git clone --depth 1 https://github.com/aipoch/medical-research-skills
agentmods
npx agentmods add skills/aipoch/medical-research-skills/lasso-logistics-analysis

Made for: Claude Code, Codex.

Wrote this? Show the measurements

A badge with what this costs and how it scanned, read live from this page, so it follows the numbers instead of freezing them. Markdown for a README, HTML for a documentation site or a project page.

agentmods badge for lasso-logistics-analysis

README.md
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Your own site
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Or the 80×15 button, for a site that already has a row of RSS and ATOM ones. Only the verdict fits; the numbers stay here.

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Your own site · 80×15
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Per session 55 Skills are progressive disclosure: only the name and description are preloaded; the body loads when the skill is used.
When invoked 2,268 The whole file, excluding the scripts and references it only reads on demand.
Security scan A 0 findings. A grade says what 26 rules found in the file — not that it is safe. Third-party audits
  • NVIDIA SkillSpector pass 7 Sept 2026
How audits are shown
Origin original No closer match found in the catalogue.
Token cost

What it costs to keep this loaded

Counted locally with the o200k_base tokenizer, which is exact for GPT models; Claude uses its own tokenizer and its counts differ. Treat this as one consistent yardstick across the catalogue rather than a bill. Prices are per million input tokens.

ModelPer sessionOnce invoked
Fable 5.1 $0.00055 $0.02268
Opus 5 $0.00028 $0.01134
Sonnet 5 $0.00011 $0.00454
Haiku 4.5 $0.00006 $0.00227

Measured 13d ago against content hash 9f8839e505a3, method: parsed. Prices are Anthropic first-party input rates as of 2026-09-12, from the pricing page.

Security

Grade A, and why

lasso-logistics-analysis scanned grade A with 0 findings against 26 rules in 11 categories — prompt injection, anti-refusal, data exfiltration, privilege escalation, supply chain, agent snooping, system-prompt leakage, SSRF and excessive agency — measured 13d ago.

A static scan of the body, not an audit. Every finding is printed with the line that produced it so you can judge whether it matters here. A mod is markdown that instructs an agent; that is exactly why what it instructs is worth reading.

Nothing flagged

None of the 26 patterns this scan looks for appear in this file: no shell pipes, no recursive deletes, no credential paths, no hidden text, no instruction-override or anti-refusal phrasing, no agent-config snooping. That is not a guarantee, it is the absence of the things that are checkable.

awesome-med-research-skills/Data Analysis/lasso-logistics-analysis/SKILL.md · 275 lines

How it starts

The opening of the file, as written. The whole thing — 275 lines — stays where its author put it; the contents beside it link to each section on GitHub.

LASSO Logistic Regression Analysis

When to Read External Files

Situation File to Read Purpose
Need algorithm details references/algorithm.md LASSO objective function, cross-validation, and interpretation
Need to run analysis scripts/main.R Execute: Rscript scripts/main.R --input_file ... --group_file ...
Encounter errors references/troubleshooting.md Common errors and solutions
Need CLI examples references/cli-guide.md Detailed CLI usage examples
Need test data tests/data/ Sample input files for testing
Need workflow implementation details scripts/run_analysis.R Inspect orchestration, outputs, and file-writing behavior
Need input-validation or error-handling details scripts/utils.R, scripts/io.R Inspect validation, parsing, logging, and standardized safeguards

Usage

Rscript scripts/main.R \
  --input_file ./expression_matrix.csv \
  --group_file ./groups.csv \
  --case_group case \
  --control_group control \
  --output_dir ./output/ \
  --nfolds 10 \
  --timeout_seconds 1800 \
  --seed 42

Arguments

Short Long Type Default Description
-i --input_file character required Expression matrix file (features as rows, samples as columns)
-g --group_file character required Group file with sample and group columns
-c --case_group character required Case class label encoded as 1
-t --control_group character required Control class label encoded as 0
-f --feature character NULL Optional feature list file or comma-separated feature names
-n --nfolds integer 10 Cross-validation folds: 3, 5, 7, 10
--cv_title character "" Optional title for the cross-validation plot
--path_title character "" Optional title for the coefficient path plot
--timeout_seconds integer 1800 Maximum elapsed runtime in seconds
-o --output_dir character ./output/ Output directory
-s --seed integer 42 Random seed for reproducibility

Read the full file on GitHub · 275 lines

Changes

What this file has done since we first saw it

Hashed on every crawl. A supply-chain change to an agent config is a question of when, not whether, so the history is kept rather than the latest state alone.

  1. 13d ago First seen · 275 lines · 55 tokens per session scan A 9f8839e505a3

Subscribe to this mod's changes

lasso-logistics-analysis is a skill published in the GitHub repository aipoch/medical-research-skills (1,860 stars, last pushed 1mo ago), licensed MIT. It adds 55 tokens to every session and 2,268 once invoked, about $0.0003 per session on Opus 5. A static security scan graded it A with 0 findings. No closer match exists in the catalogue, so it is treated as the original; first seen 2026-08-30.

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